Sodium Chloride 0.9% Neb Sol 30x3ml
It is used to thin mucus so it can be taken from the body by coughing.It is used to mix with other drugs for use in a special machine (nebulizer).It may be given to you for other reasons. Talk with the doctor.
Drug Class
Mucolytic, Respiratory tract fluid
Pharmacologic Class
Electrolyte, Osmotic agent
Pregnancy Category
Category B
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Sodium Chloride 0.9% Nebulizer Solution is a sterile salt water solution used with a nebulizer machine. It helps to moisten your airways and thin out mucus in your lungs, making it easier to cough up and breathe more comfortably.
How to Use This Medicine
Taking Your Medication Correctly
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special machine called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, away from bathrooms and heat sources. Keep all medications in a safe location, out of the reach of children and pets. Dispose of unused or expired medications by throwing them away. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposing of your medication, consult your pharmacist. You may also have access to drug take-back programs in your area.
What to Do If You Miss a Dose
If you take this medication regularly, use a missed dose as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time or take extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special machine called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, away from bathrooms and heat sources. Keep all medications in a safe location, out of the reach of children and pets. Dispose of unused or expired medications by throwing them away. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposing of your medication, consult your pharmacist. You may also have access to drug take-back programs in your area.
What to Do If You Miss a Dose
If you take this medication regularly, use a missed dose as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time or take extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
Lifestyle & Tips
- Maintain good hydration by drinking plenty of fluids, as this can also help thin mucus.
- Follow proper nebulizer cleaning and maintenance procedures to prevent infection.
Available Forms & Alternatives
Available Strengths:
- Sod Chloride 0.9% Inj, 1000ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sodium Chloride 1gm Tablets
- Sodium Chloride 0.9% Inj, 10ml
- Sodium Chloride 0.9% Inj, 50ml
- Sodium Chloride 0.9% Inj, 20ml
- Sod Chloride 0.45%/20meqkcl
- Sod Chloride 0.9% Inj, 500ml
- Sod Chloride 0.9% W/ 20meq Kcl
- Sodium Chloride 4meq/ml (23.4%) Inj
- Sod Chloride 0.9% Excel Inj 250ml
- Sodium Chloride 0.9% Neb Sol 30x3ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sod Chloride 23.4% Inj, 100ml
- Sod Chloride 0.45% Inj, 500ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 500ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sodium Chloride 3% Neb Sol 15ml
- Sod Chloride 0.9% Neb Sol 100 X 5ml
- Sodium Chloride 10% Neb Soln, 15ml
- Sod Chloride 0.9% Inj, 5ml
- Sodium Chloride 5% Ophth Oint 3.5gm
- Sod Chloride 0.9% Inj, 10ml
- Sodium Chloride 7% Neb Sol 60x4ml
- Sodium Chloride 3% Inj, 500ml
- Sod Chloride 23.4% Inj, 200ml
- Sod Chloride 0.9% Neb Sol 25 X 5ml
- Sod Chloride 0.9% Neb Sol 100 X 3ml
- Sod Chloride 0.9% Neb Sol 50 X 15ml
- Sodium Chloride 10% Neb Sol 60x4ml
- Sodium Chloride 0.9% Inj, 2ml
- Sodium Chloride 2.5meq/ml Inj, 20ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sod Chloride 4meq/ml Inj, 25x30ml
- Sod Chloride 5% Ophth Soln 15ml
- Sod Chloride 0.9% Inj, 1000ml
- Sodium Chloride 3% Neb Sol 30x4ml
- Sodium Chloride 7% Neb Sol 30x4ml
- Sodium Chloride 3% Neb Sol 60x4ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.9% Inj, 150ml
- Sodium Chloride 0.9% Inj,100ml
- Sod Chloride 0.9% Inj, 25ml
- Sod Chloride 0.9% Inj, 125ml
- Sod Chloride 0.45% Inj, 250ml
- Sod Chloride 0.45% Inj, 50ml
- Sod Chloride 0.45% Inj, 100ml
- Sod Chloride 5% Inj, 500ml
- Sod Chloride 0.45%/20meq Kcl
Dosing & Administration
Adult Dosing
Standard Dose:
3 mL to 5 mL per nebulization, 3 to 4 times daily or as needed
Dose Range:
3 - 5 mg
Condition-Specific Dosing:
as_diluent:
Typically 3 mL per nebulization with other medications
Pediatric Dosing
Neonatal:
Not established (use with caution and medical supervision)
Infant:
3 mL per nebulization, as needed or as directed by physician
Child:
3 mL per nebulization, as needed or as directed by physician
Adolescent:
3 mL to 5 mL per nebulization, as needed or as directed by physician
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Dialysis:
No specific considerations for nebulized use
Hepatic Impairment:
Mild:
No adjustment
Moderate:
No adjustment
Severe:
No adjustment
Pharmacology
Mechanism of Action
Sodium chloride 0.9% (isotonic saline) nebulizer solution works by humidifying the respiratory tract and thinning respiratory secretions, making them easier to clear. It helps to maintain the natural moisture balance in the airways and facilitates mucociliary clearance.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption
Tmax:
Not applicable for local action
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable for local action
ProteinBinding:
Not applicable for local action
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable for local action
Clearance:
Not applicable for local action
ExcretionRoute:
Primarily expectorated or absorbed locally into respiratory tract tissues
Unchanged:
Not applicable
Pharmacodynamics
OnsetOfAction:
Rapid (within minutes of inhalation)
PeakEffect:
During and immediately after administration
DurationOfAction:
Short (typically 1-4 hours, depending on individual and condition)
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. Immediately contact your doctor or seek medical attention if you notice any of the following symptoms, which could be signs of a serious allergic reaction:
Rash
Hives
Itching
Red, swollen, blistered, or peeling skin, with or without fever
Wheezing
Tightness in the chest or throat
Difficulty breathing, swallowing, or talking
Unusual hoarseness
* Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or persist, contact your doctor for guidance.
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor is available to provide medical advice about side effects.
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. Immediately contact your doctor or seek medical attention if you notice any of the following symptoms, which could be signs of a serious allergic reaction:
Rash
Hives
Itching
Red, swollen, blistered, or peeling skin, with or without fever
Wheezing
Tightness in the chest or throat
Difficulty breathing, swallowing, or talking
Unusual hoarseness
* Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or persist, contact your doctor for guidance.
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor is available to provide medical advice about side effects.
Seek Immediate Medical Attention If You Experience:
- Worsening shortness of breath or difficulty breathing after use
- Increased wheezing or chest tightness
- Persistent or severe coughing
- Signs of infection (e.g., fever, chills, increased sputum production or change in color)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health conditions to your doctor and pharmacist.
* Any health problems you have, as this information will help your doctor determine if it is safe for you to take this medication.
Remember, it is vital to verify that this medication is safe to take with all your other medications and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health conditions to your doctor and pharmacist.
* Any health problems you have, as this information will help your doctor determine if it is safe for you to take this medication.
Remember, it is vital to verify that this medication is safe to take with all your other medications and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all of your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you are pregnant, planning to become pregnant, or are currently breast-feeding, be sure to discuss this with your doctor. You and your doctor will need to carefully weigh the benefits and risks of this medication to both you and your baby.
Overdose Information
Overdose Symptoms:
- Unlikely with nebulized 0.9% sodium chloride due to minimal systemic absorption.
- Excessive use in very susceptible individuals could theoretically lead to transient hypernatremia or fluid overload, but this is extremely rare with nebulized isotonic saline.
What to Do:
Discontinue use. If symptoms occur, seek medical attention. For severe reactions, call 911 or your local emergency number. For general overdose information, call a poison control center (e.g., 1-800-222-1222).
Drug Interactions
Monitoring
Baseline Monitoring
Respiratory assessment (breath sounds, respiratory rate, effort)
Rationale: To establish baseline respiratory status before treatment
Timing: Prior to initiation of therapy
Routine Monitoring
Symptom improvement (e.g., ease of breathing, cough, sputum production)
Frequency: During and after each nebulization, or as clinically indicated
Target: Improved respiratory comfort and clearance
Action Threshold: Worsening symptoms or no improvement may require re-evaluation
Adverse effects (e.g., transient cough, bronchospasm)
Frequency: During and after each nebulization
Target: Absence of adverse effects
Action Threshold: Persistent cough, wheezing, or difficulty breathing
Symptom Monitoring
- Cough frequency and intensity
- Sputum production (amount, consistency, color)
- Shortness of breath
- Wheezing
- Chest tightness
Special Patient Groups
Pregnancy
Generally considered safe for use during pregnancy. Sodium chloride is a naturally occurring substance in the body.
Trimester-Specific Risks:
First Trimester:
Low risk
Second Trimester:
Low risk
Third Trimester:
Low risk
Lactation
Considered safe for use during lactation. Sodium chloride is a natural component of breast milk and is not expected to cause adverse effects in the infant.
Infant Risk:
Low risk (L1)
Pediatric Use
Generally safe and commonly used in pediatric patients. Dosing should be guided by clinical need and physician recommendation. Infants and young children may be more sensitive to fluid balance changes, though minimal systemic absorption makes this unlikely with nebulized isotonic saline.
Geriatric Use
Generally safe for use in geriatric patients. No specific dose adjustments are typically required. Monitor for any signs of fluid imbalance in patients with pre-existing cardiac or renal conditions, though systemic absorption is minimal.
Clinical Information
Clinical Pearls
- Often used as a diluent for other nebulized medications (e.g., bronchodilators, corticosteroids).
- Can be used to humidify airways and aid in sputum mobilization, especially in patients with thick secretions.
- While generally well-tolerated, some sensitive individuals may experience transient cough or mild bronchospasm, though this is more common with hypertonic saline.
- Ensure proper nebulizer technique and hygiene to maximize effectiveness and prevent contamination.
Alternative Therapies
- Hypertonic saline (e.g., 3%, 7%) for specific conditions like cystic fibrosis or severe bronchiolitis, where greater osmotic effect is desired.
- Other mucolytics (e.g., dornase alfa, acetylcysteine) for specific conditions requiring more potent mucus thinning.
- Humidified air or oxygen therapy.
Cost & Coverage
Average Cost:
$5 - $20 per 30x3ml unit-dose vials
Generic Available:
Yes
Insurance Coverage:
Tier 1 (Preferred Generic)
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about this medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the overdose, including the medication taken, the amount, and the time it occurred.