Sod Chloride 0.9% Inj, 10ml
It is used to flush IV sets and access devices.It may be given to you for other reasons. Talk with the doctor.
Drug Class
Electrolyte, Fluid Replacement, Diluent
Pharmacologic Class
Isotonic Solution, Electrolyte
Pregnancy Category
Not available (Generally considered safe for use as a flush/diluent; physiological component)
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Sodium Chloride 0.9% Injection, also known as normal saline, is a sterile salt water solution. It's commonly used to flush out intravenous (IV) lines to keep them clear and working properly, or to dilute other medications before they are given through the IV.
How to Use This Medicine
To use this medication correctly, follow your doctor's instructions and carefully read all accompanying information. Adhere to the dosage instructions and guidelines provided to ensure safe and effective use.
For proper storage and disposal of this medication, consult with your doctor, nurse, or pharmacist to determine the best approach for your specific situation.
If you miss a dose, contact your doctor promptly to receive guidance on the appropriate course of action to take.
For proper storage and disposal of this medication, consult with your doctor, nurse, or pharmacist to determine the best approach for your specific situation.
If you miss a dose, contact your doctor promptly to receive guidance on the appropriate course of action to take.
Lifestyle & Tips
- No specific lifestyle modifications are required when using this product as a flush.
Available Forms & Alternatives
Available Strengths:
- Sod Chloride 0.9% Inj, 1000ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sodium Chloride 1gm Tablets
- Sodium Chloride 0.9% Inj, 10ml
- Sodium Chloride 0.9% Inj, 50ml
- Sodium Chloride 0.9% Inj, 20ml
- Sod Chloride 0.45%/20meqkcl
- Sod Chloride 0.9% Inj, 500ml
- Sod Chloride 0.9% W/ 20meq Kcl
- Sodium Chloride 4meq/ml (23.4%) Inj
- Sod Chloride 0.9% Excel Inj 250ml
- Sodium Chloride 0.9% Neb Sol 30x3ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sod Chloride 23.4% Inj, 100ml
- Sod Chloride 0.45% Inj, 500ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 500ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sodium Chloride 3% Neb Sol 15ml
- Sod Chloride 0.9% Neb Sol 100 X 5ml
- Sodium Chloride 10% Neb Soln, 15ml
- Sod Chloride 0.9% Inj, 5ml
- Sodium Chloride 5% Ophth Oint 3.5gm
- Sod Chloride 0.9% Inj, 10ml
- Sodium Chloride 7% Neb Sol 60x4ml
- Sodium Chloride 3% Inj, 500ml
- Sod Chloride 23.4% Inj, 200ml
- Sod Chloride 0.9% Neb Sol 25 X 5ml
- Sod Chloride 0.9% Neb Sol 100 X 3ml
- Sod Chloride 0.9% Neb Sol 50 X 15ml
- Sodium Chloride 10% Neb Sol 60x4ml
- Sodium Chloride 0.9% Inj, 2ml
- Sodium Chloride 2.5meq/ml Inj, 20ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sod Chloride 4meq/ml Inj, 25x30ml
- Sod Chloride 5% Ophth Soln 15ml
- Sod Chloride 0.9% Inj, 1000ml
- Sodium Chloride 3% Neb Sol 30x4ml
- Sodium Chloride 7% Neb Sol 30x4ml
- Sodium Chloride 3% Neb Sol 60x4ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.9% Inj, 150ml
- Sodium Chloride 0.9% Inj,100ml
- Sod Chloride 0.9% Inj, 25ml
- Sod Chloride 0.9% Inj, 125ml
- Sod Chloride 0.45% Inj, 250ml
- Sod Chloride 0.45% Inj, 50ml
- Sod Chloride 0.45% Inj, 100ml
- Sod Chloride 5% Inj, 500ml
- Sod Chloride 0.45%/20meq Kcl
Dosing & Administration
Adult Dosing
Standard Dose:
For flushing intravenous catheters: 1-10 mL as needed to maintain patency or clear medication residue.
Dose Range:
1 - 10 mg
Condition-Specific Dosing:
IV_Flush:
1-10 mL per flush, as needed
Diluent:
Volume as required for medication dilution
Pediatric Dosing
Neonatal:
For flushing intravenous catheters: 0.5-2 mL as needed.
Infant:
For flushing intravenous catheters: 1-3 mL as needed.
Child:
For flushing intravenous catheters: 1-5 mL as needed.
Adolescent:
For flushing intravenous catheters: 1-10 mL as needed.
Dose Adjustments
Renal Impairment:
Mild:
No specific adjustment needed for flush volumes.
Moderate:
No specific adjustment needed for flush volumes; monitor for fluid overload if larger volumes are administered.
Severe:
No specific adjustment needed for flush volumes; use with caution and monitor for fluid overload, especially in anuric patients.
Dialysis:
No specific adjustment needed for flush volumes; monitor fluid balance closely.
Hepatic Impairment:
Mild:
No specific adjustment needed.
Moderate:
No specific adjustment needed.
Severe:
No specific adjustment needed; monitor for fluid overload if larger volumes are administered, especially in patients with ascites or edema.
Pharmacology
Mechanism of Action
Sodium Chloride 0.9% Injection is an isotonic solution that provides water and electrolytes (sodium and chloride) to maintain osmotic pressure. When used as a flush, it serves as a vehicle to clear intravenous lines, maintain patency, and prevent mixing of incompatible medications.
Pharmacokinetics
Absorption:
Bioavailability:
100% (intravenous)
Tmax:
Immediate (intravenous)
FoodEffect:
Not applicable (intravenous administration)
Distribution:
Vd:
Approximately 0.2 L/kg (extracellular fluid volume)
ProteinBinding:
Not applicable (ions)
CnssPenetration:
Yes (distributes into CSF)
Elimination:
HalfLife:
Not applicable (continuously regulated by kidneys)
Clearance:
Renal clearance of sodium and chloride is highly variable and dependent on physiological needs.
ExcretionRoute:
Renal (primarily)
Unchanged:
100% (ions are excreted as such)
Pharmacodynamics
OnsetOfAction:
Immediate (upon intravenous administration)
PeakEffect:
Immediate
DurationOfAction:
Transient (ions are rapidly distributed and excreted, but the effect of flushing is immediate and localized to the catheter)
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention, as they may be signs of a severe and potentially life-threatening reaction:
- Signs of an allergic reaction, such as rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, consult your doctor. For medical advice about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention, as they may be signs of a severe and potentially life-threatening reaction:
- Signs of an allergic reaction, such as rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, consult your doctor. For medical advice about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Pain, swelling, or redness at the IV site
- Difficulty breathing or shortness of breath
- Swelling in your hands, ankles, or feet
- Unusual weight gain
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Be sure to describe the allergic reaction you experienced, including the symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to discuss all your medications and health conditions with your doctor and pharmacist to ensure safe use.
Any health problems you have, as they may interact with this medication. Your doctor and pharmacist need to be aware of all your health issues to determine if it is safe for you to take this medication.
Do not start, stop, or change the dose of any medication without first consulting your doctor. This includes any changes to your current medication regimen, as well as the addition of any new medications, including OTC drugs, natural products, and vitamins.
It is essential to inform your doctor about the following:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Be sure to describe the allergic reaction you experienced, including the symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to discuss all your medications and health conditions with your doctor and pharmacist to ensure safe use.
Any health problems you have, as they may interact with this medication. Your doctor and pharmacist need to be aware of all your health issues to determine if it is safe for you to take this medication.
Do not start, stop, or change the dose of any medication without first consulting your doctor. This includes any changes to your current medication regimen, as well as the addition of any new medications, including OTC drugs, natural products, and vitamins.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you are pregnant, planning to become pregnant, or are breastfeeding, you must discuss this with your doctor. This conversation will help you understand the potential benefits and risks of this medication to both you and your baby, allowing you to make an informed decision.
Overdose Information
Overdose Symptoms:
- Fluid overload (e.g., edema, pulmonary congestion, hypertension)
- Electrolyte imbalance (e.g., hypernatremia, hyperchloremia, metabolic acidosis)
What to Do:
Discontinue administration. Administer diuretics if fluid overload is present. Correct electrolyte imbalances as needed. Call 1-800-222-1222 (Poison Control) for severe symptoms or concerns.
Drug Interactions
Monitoring
Baseline Monitoring
Fluid status (e.g., edema, lung sounds)
Rationale: To assess baseline hydration and risk of fluid overload, especially if larger volumes are anticipated or in patients with compromised cardiac/renal function.
Timing: Prior to initiation of therapy (if continuous infusion) or as clinically indicated for flush use.
Routine Monitoring
Site of injection/catheter patency
Frequency: Before and after each flush/medication administration
Target: Patent, no signs of infiltration or phlebitis
Action Threshold: Infiltration, pain, swelling, redness, resistance to flush
Signs of fluid overload (e.g., dyspnea, crackles, edema)
Frequency: As clinically indicated, especially in vulnerable patients
Target: Absence of signs
Action Threshold: Presence of signs of fluid overload
Symptom Monitoring
- Swelling or pain at injection site
- Difficulty breathing (dyspnea)
- Swelling in extremities (edema)
- Unusual weight gain
Special Patient Groups
Pregnancy
Generally considered safe for use as a flush or diluent during pregnancy. Sodium chloride is a physiological component of the body.
Trimester-Specific Risks:
First Trimester:
Low risk
Second Trimester:
Low risk
Third Trimester:
Low risk
Lactation
Considered safe for use during lactation. Sodium chloride is a physiological component and is not expected to harm the breastfed infant.
Infant Risk:
Low risk
Pediatric Use
Generally safe for use in pediatric patients, including neonates, for flushing IV lines. Dosing should be adjusted based on patient size and clinical need to avoid fluid overload.
Geriatric Use
Generally safe for use in geriatric patients. However, elderly patients may be more susceptible to fluid overload due to age-related decreases in renal and cardiac function; monitor fluid status closely if larger volumes are administered.
Clinical Information
Clinical Pearls
- Sodium Chloride 0.9% is isotonic with human plasma, making it the most common and preferred solution for flushing IV catheters.
- Always check the compatibility of medications before diluting them with Sodium Chloride 0.9%.
- Ensure proper aseptic technique when flushing IV lines to prevent infection.
- Pre-filled syringes are convenient and reduce the risk of contamination compared to drawing from vials.
Alternative Therapies
- Heparin flush (for specific catheter types or situations where anticoagulation is desired, though saline is often preferred due to lower risk profile)
- Dextrose 5% in Water (D5W) (used as a diluent for some medications, but not typically for routine flushing due to hypotonicity and potential for vein irritation)
Cost & Coverage
Average Cost:
$0.50 - $5.00 per 10 mL vial/syringe
Generic Available:
Yes
Insurance Coverage:
Tier 1 (Generic)
General Drug Facts
If your symptoms or health problems persist or worsen, it is essential to contact your doctor for further guidance. To ensure safe use, never share your medication with others, and do not take medication prescribed for someone else. Store all medications in a secure location, out of reach of children and pets, to prevent accidental ingestion. Dispose of unused or expired medications properly. Unless instructed to do so by a healthcare professional, do not flush medications down the toilet or pour them down the drain. If you are unsure about the proper disposal method, consult your pharmacist for guidance. Many communities have drug take-back programs, which your pharmacist can help you locate. Some medications may come with an additional patient information leaflet; check with your pharmacist to see if this applies to your prescription. If you have any questions or concerns about your medication, discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately contact your local poison control center or seek emergency medical attention. Be prepared to provide information about the medication taken, the amount, and the time it was taken, as this will aid in providing appropriate care.