Sod Chloride 0.9% Neb Sol 50 X 15ml
It is used to thin mucus so it can be taken from the body by coughing.It is used to mix with other drugs for use in a special machine (nebulizer).It may be given to you for other reasons. Talk with the doctor.
Drug Class
Electrolyte solution; Respiratory tract agent
Pharmacologic Class
Isotonic solution; Mucolytic (indirect)
Pregnancy Category
Category A
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
This is a sterile salt water solution that you put into a nebulizer machine. When you breathe it in, it helps to moisten your airways, making it easier to cough up mucus and breathe more comfortably. It can also be used to mix with other medicines for your nebulizer.
How to Use This Medicine
Taking Your Medication Correctly
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special machine called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, avoiding the bathroom. Protect it from heat and keep it out of reach of children and pets. When you no longer need this medication or it has expired, dispose of it properly. Do not flush it down the toilet or pour it down the drain unless instructed to do so. If you have questions about disposal, consult your pharmacist. You may also have access to drug take-back programs in your area.
What to Do If You Miss a Dose
If you take this medication regularly, use a missed dose as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time or extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special machine called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, avoiding the bathroom. Protect it from heat and keep it out of reach of children and pets. When you no longer need this medication or it has expired, dispose of it properly. Do not flush it down the toilet or pour it down the drain unless instructed to do so. If you have questions about disposal, consult your pharmacist. You may also have access to drug take-back programs in your area.
What to Do If You Miss a Dose
If you take this medication regularly, use a missed dose as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time or extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
Lifestyle & Tips
- Maintain good overall hydration by drinking plenty of fluids.
- Follow proper nebulizer cleaning and maintenance procedures.
- Do not mix with other medications unless directed by your healthcare provider.
Available Forms & Alternatives
Available Strengths:
- Sod Chloride 0.9% Inj, 1000ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sodium Chloride 1gm Tablets
- Sodium Chloride 0.9% Inj, 10ml
- Sodium Chloride 0.9% Inj, 50ml
- Sodium Chloride 0.9% Inj, 20ml
- Sod Chloride 0.45%/20meqkcl
- Sod Chloride 0.9% Inj, 500ml
- Sod Chloride 0.9% W/ 20meq Kcl
- Sodium Chloride 4meq/ml (23.4%) Inj
- Sod Chloride 0.9% Excel Inj 250ml
- Sodium Chloride 0.9% Neb Sol 30x3ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sod Chloride 23.4% Inj, 100ml
- Sod Chloride 0.45% Inj, 500ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 500ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sodium Chloride 3% Neb Sol 15ml
- Sod Chloride 0.9% Neb Sol 100 X 5ml
- Sodium Chloride 10% Neb Soln, 15ml
- Sod Chloride 0.9% Inj, 5ml
- Sodium Chloride 5% Ophth Oint 3.5gm
- Sod Chloride 0.9% Inj, 10ml
- Sodium Chloride 7% Neb Sol 60x4ml
- Sodium Chloride 3% Inj, 500ml
- Sod Chloride 23.4% Inj, 200ml
- Sod Chloride 0.9% Neb Sol 25 X 5ml
- Sod Chloride 0.9% Neb Sol 100 X 3ml
- Sod Chloride 0.9% Neb Sol 50 X 15ml
- Sodium Chloride 10% Neb Sol 60x4ml
- Sodium Chloride 0.9% Inj, 2ml
- Sodium Chloride 2.5meq/ml Inj, 20ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sod Chloride 4meq/ml Inj, 25x30ml
- Sod Chloride 5% Ophth Soln 15ml
- Sod Chloride 0.9% Inj, 1000ml
- Sodium Chloride 3% Neb Sol 30x4ml
- Sodium Chloride 7% Neb Sol 30x4ml
- Sodium Chloride 3% Neb Sol 60x4ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.9% Inj, 150ml
- Sodium Chloride 0.9% Inj,100ml
- Sod Chloride 0.9% Inj, 25ml
- Sod Chloride 0.9% Inj, 125ml
- Sod Chloride 0.45% Inj, 250ml
- Sod Chloride 0.45% Inj, 50ml
- Sod Chloride 0.45% Inj, 100ml
- Sod Chloride 5% Inj, 500ml
- Sod Chloride 0.45%/20meq Kcl
Dosing & Administration
Adult Dosing
Standard Dose:
2.5 mL to 5 mL of 0.9% solution, 2 to 4 times daily or as needed
Dose Range:
2.5 - 5 mg
Condition-Specific Dosing:
As diluent for other nebulized medications:
Volume as required by the primary medication
Pediatric Dosing
Neonatal:
Not established (use with caution and medical supervision)
Infant:
2.5 mL to 5 mL of 0.9% solution, 2 to 4 times daily or as needed (often as diluent)
Child:
2.5 mL to 5 mL of 0.9% solution, 2 to 4 times daily or as needed (often as diluent)
Adolescent:
2.5 mL to 5 mL of 0.9% solution, 2 to 4 times daily or as needed (often as diluent)
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Dialysis:
No specific considerations for nebulized use
Hepatic Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Pharmacology
Mechanism of Action
Sodium chloride 0.9% nebulizer solution is an isotonic saline solution that, when inhaled, helps to hydrate the respiratory tract, loosen and thin tenacious mucus secretions, and facilitate their clearance. It can also serve as a diluent for other nebulized medications.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption (primarily local action)
Tmax:
Not applicable (local effect)
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable (local action)
ProteinBinding:
Not applicable
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable (local action)
Clearance:
Not applicable
ExcretionRoute:
Expectorated or absorbed locally by respiratory mucosa
Unchanged:
Not applicable
Pharmacodynamics
OnsetOfAction:
Rapid (within minutes of inhalation)
PeakEffect:
During and immediately after inhalation
DurationOfAction:
Short (effects dissipate as hydration diminishes, typically 1-2 hours)
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Attention Immediately
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek medical help right away:
- Signs of an allergic reaction, such as:
- Rash
- Hives
- Itching
- Red, swollen, blistered, or peeling skin (with or without fever)
- Wheezing
- Tightness in the chest or throat
- Trouble breathing, swallowing, or talking
- Unusual hoarseness
- Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, discuss them with your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor is available to provide medical advice about side effects.
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek medical help right away:
- Signs of an allergic reaction, such as:
- Rash
- Hives
- Itching
- Red, swollen, blistered, or peeling skin (with or without fever)
- Wheezing
- Tightness in the chest or throat
- Trouble breathing, swallowing, or talking
- Unusual hoarseness
- Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, discuss them with your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor is available to provide medical advice about side effects.
Seek Immediate Medical Attention If You Experience:
- Worsening shortness of breath or wheezing after use
- Increased coughing or chest tightness that does not resolve
- Signs of infection (e.g., fever, chills, increased sputum production or change in color)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This information will help your doctor assess potential interactions between this medication and other substances you are taking.
* Any health problems you have, as they may affect the safety and efficacy of this medication.
Remember, this is not an exhaustive list of all possible interactions. To ensure your safety, it is crucial to consult with your doctor and pharmacist about all your medications and health conditions before taking this drug. Never start, stop, or change the dose of any medication without first discussing it with your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This information will help your doctor assess potential interactions between this medication and other substances you are taking.
* Any health problems you have, as they may affect the safety and efficacy of this medication.
Remember, this is not an exhaustive list of all possible interactions. To ensure your safety, it is crucial to consult with your doctor and pharmacist about all your medications and health conditions before taking this drug. Never start, stop, or change the dose of any medication without first discussing it with your doctor.
Precautions & Cautions
It is essential to inform all of your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you are pregnant, planning to become pregnant, or are currently breast-feeding, be sure to discuss this with your doctor. You and your doctor will need to carefully weigh the benefits and risks of using this medication during pregnancy or breast-feeding to make an informed decision about its use.
Overdose Information
Overdose Symptoms:
- Unlikely with nebulized 0.9% sodium chloride due to minimal systemic absorption. Excessive use might theoretically lead to transient coughing or irritation.
What to Do:
Discontinue use. If symptoms persist or worsen, seek medical attention. Call 1-800-222-1222 for poison control.
Drug Interactions
Monitoring
Baseline Monitoring
Respiratory status (e.g., breath sounds, cough, sputum production)
Rationale: To establish baseline for assessing treatment effectiveness and identify any adverse reactions.
Timing: Prior to initiation of therapy
Routine Monitoring
Effectiveness of mucus clearance
Frequency: Daily or as needed
Target: Improved cough, easier breathing, reduced sputum viscosity
Action Threshold: Lack of improvement or worsening symptoms may require re-evaluation of therapy or underlying condition.
Patient comfort and tolerance
Frequency: During and after each nebulization
Target: No significant discomfort, coughing, or bronchospasm
Action Threshold: Persistent coughing, chest tightness, or shortness of breath may indicate intolerance or need for bronchodilator pre-treatment.
Symptom Monitoring
- Cough frequency and productivity
- Sputum consistency and volume
- Shortness of breath
- Wheezing or chest tightness
Special Patient Groups
Pregnancy
Considered safe for use during pregnancy. Sodium chloride is a naturally occurring substance and 0.9% solution is isotonic.
Trimester-Specific Risks:
First Trimester:
No known risks
Second Trimester:
No known risks
Third Trimester:
No known risks
Lactation
Considered safe for use during lactation. Minimal systemic absorption means negligible transfer into breast milk.
Infant Risk:
No known risk to the breastfed infant.
Pediatric Use
Generally safe and well-tolerated in pediatric patients. Dosing is typically based on the volume needed for nebulization, similar to adults. Use with appropriate nebulizer equipment for children.
Geriatric Use
Generally safe and well-tolerated in geriatric patients. No specific dose adjustments are typically required. Monitor for comfort and effectiveness.
Clinical Information
Clinical Pearls
- 0.9% Sodium Chloride Nebulizer Solution is often referred to as 'normal saline' for nebulization.
- It is commonly used as a diluent for other nebulized medications (e.g., bronchodilators, corticosteroids).
- Can be used alone to help hydrate airways and loosen secretions, particularly in dry cough or thick mucus conditions.
- While generally very safe, some individuals, especially those with highly reactive airways, may experience transient coughing or mild bronchospasm, though this is more common with hypertonic saline.
- Ensure proper nebulizer hygiene to prevent contamination.
Alternative Therapies
- Hypertonic saline nebulizer solutions (e.g., 3%, 7% NaCl) for more aggressive mucolytic effect (requires careful monitoring for bronchospasm)
- Dornase alfa (Pulmozyme) for cystic fibrosis patients
- Oral hydration and humidification (e.g., cool mist humidifier)
Cost & Coverage
Average Cost:
$10 - $30 per 50 x 15mL vials
Generic Available:
Yes
Insurance Coverage:
Tier 1 (Preferred Generic)
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When reporting the incident, be prepared to provide details about the medication taken, the amount, and the time it occurred.