Sod Chloride 0.9% Neb Sol 100 X 3ml
It is used to thin mucus so it can be taken from the body by coughing.It is used to mix with other drugs for use in a special machine (nebulizer).It may be given to you for other reasons. Talk with the doctor.
Drug Class
Respiratory Hydrating Agent; Mucolytic Adjunct
Pharmacologic Class
Electrolyte Solution; Osmotic Agent
Pregnancy Category
Category A
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Sodium Chloride 0.9% Nebulizer Solution is a sterile salt water solution that you breathe in using a nebulizer machine. It helps to add moisture to your airways, making mucus thinner and easier to cough up, which can help you breathe more easily. It's also commonly used to mix with other medicines that you need to breathe in.
How to Use This Medicine
Taking Your Medication Correctly
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special device called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, avoiding the bathroom. Protect it from heat and keep it out of reach of children and pets. When disposing of unused or expired medication, do not flush it down the toilet or pour it down the drain unless instructed to do so. Instead, ask your pharmacist about the best way to dispose of it, or check if there are any drug take-back programs in your area.
Missing a Dose
If you take this medication regularly, take a missed dose as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time or take extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
To use this medication properly, follow your doctor's instructions and read all the information provided. You will inhale this medication through your mouth using a special device called a nebulizer. Your doctor will show you how to use the nebulizer correctly.
Storing and Disposing of Your Medication
Store this medication at room temperature in a dry place, avoiding the bathroom. Protect it from heat and keep it out of reach of children and pets. When disposing of unused or expired medication, do not flush it down the toilet or pour it down the drain unless instructed to do so. Instead, ask your pharmacist about the best way to dispose of it, or check if there are any drug take-back programs in your area.
Missing a Dose
If you take this medication regularly, take a missed dose as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time or take extra doses. If you use this medication as needed, do not use it more frequently than directed by your doctor.
Lifestyle & Tips
- Maintain good hydration by drinking plenty of fluids.
- Follow proper nebulizer cleaning and maintenance procedures.
- Do not mix with other medications unless directed by your healthcare provider.
Available Forms & Alternatives
Available Strengths:
- Sod Chloride 0.9% Inj, 1000ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sodium Chloride 1gm Tablets
- Sodium Chloride 0.9% Inj, 10ml
- Sodium Chloride 0.9% Inj, 50ml
- Sodium Chloride 0.9% Inj, 20ml
- Sod Chloride 0.45%/20meqkcl
- Sod Chloride 0.9% Inj, 500ml
- Sod Chloride 0.9% W/ 20meq Kcl
- Sodium Chloride 4meq/ml (23.4%) Inj
- Sod Chloride 0.9% Excel Inj 250ml
- Sodium Chloride 0.9% Neb Sol 30x3ml
- Sod Chloride 0.9% Inj, 100ml
- Sod Chloride 0.9% Inj, 50ml
- Sod Chloride 23.4% Inj, 100ml
- Sod Chloride 0.45% Inj, 500ml
- Sod Chloride 0.45% Inj, 1000ml
- Sod Chloride 0.9% Inj, 500ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sodium Chloride 3% Neb Sol 15ml
- Sod Chloride 0.9% Neb Sol 100 X 5ml
- Sodium Chloride 10% Neb Soln, 15ml
- Sod Chloride 0.9% Inj, 5ml
- Sodium Chloride 5% Ophth Oint 3.5gm
- Sod Chloride 0.9% Inj, 10ml
- Sodium Chloride 7% Neb Sol 60x4ml
- Sodium Chloride 3% Inj, 500ml
- Sod Chloride 23.4% Inj, 200ml
- Sod Chloride 0.9% Neb Sol 25 X 5ml
- Sod Chloride 0.9% Neb Sol 100 X 3ml
- Sod Chloride 0.9% Neb Sol 50 X 15ml
- Sodium Chloride 10% Neb Sol 60x4ml
- Sodium Chloride 0.9% Inj, 2ml
- Sodium Chloride 2.5meq/ml Inj, 20ml
- Sodium Chloride 2.5meq/ml Inj, 40ml
- Sod Chloride 4meq/ml Inj, 25x30ml
- Sod Chloride 5% Ophth Soln 15ml
- Sod Chloride 0.9% Inj, 1000ml
- Sodium Chloride 3% Neb Sol 30x4ml
- Sodium Chloride 7% Neb Sol 30x4ml
- Sodium Chloride 3% Neb Sol 60x4ml
- Sod Chloride 0.9% Inj, 250ml
- Sod Chloride 0.9% Inj, 150ml
- Sodium Chloride 0.9% Inj,100ml
- Sod Chloride 0.9% Inj, 25ml
- Sod Chloride 0.9% Inj, 125ml
- Sod Chloride 0.45% Inj, 250ml
- Sod Chloride 0.45% Inj, 50ml
- Sod Chloride 0.45% Inj, 100ml
- Sod Chloride 5% Inj, 500ml
- Sod Chloride 0.45%/20meq Kcl
Dosing & Administration
Adult Dosing
Standard Dose:
3 mL (one 3 mL ampule) per nebulization session, 3-4 times daily or as directed by healthcare professional.
Dose Range:
3 - 5 mg
Condition-Specific Dosing:
as_diluent:
As needed to dilute other nebulized medications to a total volume of 3-5 mL.
Pediatric Dosing
Neonatal:
Dosing as directed by healthcare professional, typically 1-3 mL per nebulization session.
Infant:
Dosing as directed by healthcare professional, typically 1-3 mL per nebulization session.
Child:
Dosing as directed by healthcare professional, typically 3 mL per nebulization session.
Adolescent:
Dosing as directed by healthcare professional, typically 3 mL per nebulization session.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed.
Moderate:
No adjustment needed.
Severe:
No adjustment needed.
Dialysis:
No specific considerations as systemic absorption is minimal.
Hepatic Impairment:
Mild:
No adjustment needed.
Moderate:
No adjustment needed.
Severe:
No adjustment needed.
Pharmacology
Mechanism of Action
Sodium chloride 0.9% nebulizer solution is an isotonic saline solution. When inhaled via nebulization, it helps to hydrate the respiratory tract, loosen and thin tenacious mucus secretions, making them easier to clear. It can also act as a diluent for other nebulized medications.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption when nebulized.
Tmax:
Not applicable (local action)
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable (minimal systemic distribution)
ProteinBinding:
Not applicable (minimal systemic distribution)
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable (minimal systemic absorption)
Clearance:
Not applicable (minimal systemic absorption)
ExcretionRoute:
Primarily local action, cleared by mucociliary escalator or expectoration.
Unchanged:
Not applicable
Pharmacodynamics
OnsetOfAction:
Rapid (local effect, within minutes of inhalation)
PeakEffect:
Not applicable (continuous local effect during administration)
DurationOfAction:
Short (effect lasts during and shortly after nebulization, depending on airway hydration and mucus clearance)
Confidence:
High
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek immediate medical attention:
* Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have any side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice about side effects.
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek immediate medical attention:
* Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have any side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice about side effects.
Seek Immediate Medical Attention If You Experience:
- Increased shortness of breath or wheezing after use (may indicate bronchospasm, especially in sensitive individuals)
- Chest tightness
- Persistent coughing or irritation
- Signs of infection if solution becomes contaminated (e.g., fever, worsening cough with colored sputum)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health issues to your doctor and pharmacist.
Any health problems you have, as they may interact with this medication. Your doctor and pharmacist need to be aware of your complete medical profile to ensure safe treatment.
Do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication in conjunction with your other medications and health conditions.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, any of its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health issues to your doctor and pharmacist.
Any health problems you have, as they may interact with this medication. Your doctor and pharmacist need to be aware of your complete medical profile to ensure safe treatment.
Do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication in conjunction with your other medications and health conditions.
Precautions & Cautions
It is essential to inform all of your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you are pregnant, planning to become pregnant, or are breast-feeding, be sure to discuss this with your doctor. You and your doctor will need to carefully weigh the benefits and risks of using this medication during this time to ensure the best possible outcome for both you and your baby.
Overdose Information
Overdose Symptoms:
- Overdose with nebulized 0.9% sodium chloride is highly unlikely due to minimal systemic absorption. Excessive use might lead to temporary airway irritation or increased coughing.
What to Do:
Discontinue use. If symptoms persist or worsen, seek medical attention. Call 1-800-222-1222 for Poison Control.
Drug Interactions
Monitoring
Baseline Monitoring
Respiratory assessment (breath sounds, cough, sputum production)
Rationale: To establish baseline respiratory status and evaluate effectiveness of therapy.
Timing: Prior to initiation of therapy.
Routine Monitoring
Patient comfort and tolerance
Frequency: During and after each nebulization session
Target: Absence of significant discomfort or adverse effects
Action Threshold: If patient experiences increased coughing, bronchospasm, or discomfort, discontinue use and assess.
Effectiveness of mucus clearance
Frequency: Daily or as needed
Target: Improved ease of breathing, reduced cough, easier expectoration of sputum
Action Threshold: If no improvement or worsening of respiratory symptoms, re-evaluate treatment plan.
Symptom Monitoring
- Ease of breathing
- Cough frequency and productivity
- Sputum consistency and volume
- Presence of wheezing or shortness of breath
Special Patient Groups
Pregnancy
Sodium chloride 0.9% nebulizer solution is considered safe for use during pregnancy. It is a physiological solution with minimal systemic absorption when inhaled.
Trimester-Specific Risks:
First Trimester:
No known risks.
Second Trimester:
No known risks.
Third Trimester:
No known risks.
Lactation
Sodium chloride 0.9% nebulizer solution is considered safe for use during lactation. It is a physiological solution with minimal systemic absorption, making transfer to breast milk unlikely to be clinically significant.
Infant Risk:
Low risk (L1 - compatible).
Pediatric Use
Generally safe and widely used in pediatric populations, including neonates, for airway hydration and as a diluent for other nebulized medications. Dosing should be guided by a healthcare professional.
Geriatric Use
Generally safe for use in geriatric patients. No specific dose adjustments or precautions are typically required beyond standard monitoring for respiratory comfort.
Clinical Information
Clinical Pearls
- Sodium chloride 0.9% nebulizer solution is a versatile and safe agent for respiratory therapy, primarily used for airway hydration and as a diluent.
- It is often preferred over sterile water for nebulization due to its isotonicity, which reduces the risk of bronchospasm.
- Ensure proper nebulizer hygiene to prevent contamination of the solution and subsequent respiratory infections.
- While generally safe, some sensitive individuals (e.g., those with hyperreactive airways) may experience transient cough or mild bronchospasm, especially with initial use. If this occurs, consider pre-treatment with a bronchodilator if clinically appropriate and directed by a physician.
Alternative Therapies
- Mucolytics (e.g., acetylcysteine, dornase alfa - for specific conditions)
- Bronchodilators (e.g., albuterol, ipratropium - for airway constriction)
- Expectorants (e.g., guaifenesin - oral agents)
Cost & Coverage
Average Cost:
$10 - $30 per 100 x 3mL ampules
Generic Available:
Yes
Insurance Coverage:
Generally covered by most prescription drug plans (Tier 1 or Preferred Generic)
General Drug Facts
If your symptoms or health condition do not improve or worsen over time, it is essential to contact your doctor for further evaluation and guidance. To ensure your safety and the effectiveness of your treatment, never share your medication with others or take someone else's medication. It's also important to note that some medications may come with additional patient information leaflets, so be sure to check with your pharmacist for more details. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider for clarification and support. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide critical information, including the name of the medication taken, the amount, and the time it was taken, to ensure you receive the most effective treatment.