Humalog Tempo Pen 100u/ml Inj 3ml

Insulin lispro is a rapid-acting human insulin analog that lowers blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.

Urgent Side Effects: Seek Medical Help Right Away

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Note: In rare cases, allergic reactions can be fatal.
Signs of low potassium levels, including:
+ Muscle pain or weakness
+ Muscle cramps
+ An irregular heartbeat
Signs of infection, such as:
+ Fever
+ Chills
+ Severe sore throat
+ Ear or sinus pain
+ Cough
+ Increased or changed sputum production
+ Painful urination
+ Mouth sores
+ Wounds that won't heal
Thick skin, pits, or lumps at the injection site
Swelling in the arms or legs
Low blood sugar, which may cause:
+ Dizziness or fainting
+ Blurred vision
+ Mood changes
+ Slurred speech
+ Headache
+ Feeling sleepy or weak
+ Shaking
+ Fast heartbeat
+ Confusion
+ Hunger
+ Sweating
+ Seizures
If you experience any of these symptoms, contact your doctor immediately. If you have low blood sugar, follow your doctor's instructions, which may include taking glucose tablets, liquid glucose, or certain fruit juices.

Other Possible Side Effects

Like all medications, this drug can cause side effects. Many people may not experience any side effects or may only have mild ones. If you notice any of the following side effects or any other symptoms that bother you or don't go away, contact your doctor:

Weight gain
Flu-like symptoms
Nose or throat irritation
Common cold symptoms
Headache
Cough
Upset stomach
Stomach pain or diarrhea
Feeling tired or weak
* Irritation at the injection site

This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you have low blood sugar (hypoglycemia), as this may affect your treatment plan.

This medication can interact with other medications and health conditions. To ensure your safety, it is crucial to provide your doctor and pharmacist with a comprehensive list of:

All prescription and over-the-counter (OTC) medications you are taking
Any natural products or supplements you are using
Vitamins you are taking
Any health problems you have

Before starting, stopping, or changing the dose of any medication, including this one, you must consult with your doctor to confirm that it is safe to do so. This will help prevent potential interactions and ensure the safe use of this medication.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.

This drug may cause low blood sugar, which can lead to seizures, loss of consciousness, permanent brain damage, and even death if not properly managed. It is crucial to discuss this risk with your doctor. Additionally, this medication may cause low blood potassium levels, which can result in abnormal heart rhythms, severe breathing problems, and potentially death if left untreated. If you experience any symptoms, consult your doctor promptly.

Until you understand how this medication affects you, avoid driving and other activities that require your full attention. Certain diabetes medications, such as pioglitazone or rosiglitazone, may increase the risk of heart failure or worsen existing heart failure, especially when combined with insulin. If you are taking one of these medications, consult your doctor to discuss the potential risks.

Ensure you are using the correct insulin product, as they come in various containers, including vials, cartridges, and pens. If you are unsure about measuring or preparing your dose, consult your doctor or pharmacist for guidance.

During stressful events, such as fever, infection, injury, or surgery, it may be more challenging to control your blood sugar levels. Changes in physical activity, exercise, or diet can also impact your blood sugar levels.

Wear a medical alert identification to ensure prompt care in case of an emergency. Avoid driving if you have experienced low blood sugar, as it increases the risk of accidents. Monitor your blood sugar levels as directed by your doctor and undergo regular blood tests as recommended.

Before consuming alcohol or using products containing alcohol, consult your doctor to discuss potential risks. Never share your insulin product, including pens, cartridge devices, needles, or syringes, with others, even if the needle has been changed, as this can transmit infections.

If you are 65 or older, use this medication with caution, as you may be more susceptible to side effects. Inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, as you will need to discuss the benefits and risks to both you and your baby.

• Beta-blockers (can mask symptoms of hypoglycemia)
• Alcohol (can potentiate hypoglycemic effect)

• Oral antidiabetic agents (increased risk of hypoglycemia)
• ACE inhibitors (increased risk of hypoglycemia)
• Angiotensin receptor blockers (increased risk of hypoglycemia)
• Disopyramide (increased risk of hypoglycemia)
• Fibrates (increased risk of hypoglycemia)
• Fluoxetine (increased risk of hypoglycemia)
• MAOIs (increased risk of hypoglycemia)
• Pentoxifylline (increased risk of hypoglycemia)
• Propoxyphene (increased risk of hypoglycemia)
• Salicylates (e.g., aspirin, increased risk of hypoglycemia)
• Somatostatin analogs (e.g., octreotide, increased risk of hypoglycemia)
• Sulfonamide antibiotics (increased risk of hypoglycemia)
• Corticosteroids (may increase blood glucose, requiring higher insulin doses)
• Danazol (may increase blood glucose, requiring higher insulin doses)
• Diazoxide (may increase blood glucose, requiring higher insulin doses)
• Diuretics (e.g., thiazides, loop diuretics; may increase blood glucose, requiring higher insulin doses)
• Glucagon (may increase blood glucose, requiring higher insulin doses)
• Isoniazid (may increase blood glucose, requiring higher insulin doses)
• Estrogens (e.g., oral contraceptives; may increase blood glucose, requiring higher insulin doses)
• Phenothiazines (may increase blood glucose, requiring higher insulin doses)
• Somatropin (may increase blood glucose, requiring higher insulin doses)
• Sympathomimetics (e.g., epinephrine, albuterol; may increase blood glucose, requiring higher insulin doses)
• Thyroid hormones (may increase blood glucose, requiring higher insulin doses)
• Atypical antipsychotics (e.g., olanzapine, clozapine; may increase blood glucose, requiring higher insulin doses)
• Protease inhibitors (may increase blood glucose, requiring higher insulin doses)

• Symptoms of hypoglycemia: sweating, tremor, dizziness, confusion, hunger, irritability, blurred vision, palpitations, headache, weakness.
• Symptoms of hyperglycemia: increased thirst (polydipsia), frequent urination (polyuria), increased hunger (polyphagia), fatigue, blurred vision, unexplained weight loss.

Insulin lispro is generally considered safe and is often the preferred insulin for managing diabetes during pregnancy, including gestational diabetes. Careful monitoring of blood glucose is essential to achieve optimal glycemic control and reduce risks to both mother and fetus.

Insulin lispro is compatible with breastfeeding. Insulin is a normal component of breast milk, but the amount transferred is negligible and not expected to harm the breastfed infant. Maternal insulin requirements may change during lactation.

Insulin lispro is approved for use in pediatric patients with diabetes. Dosing is highly individualized based on age, weight, activity level, and glycemic control goals. Careful monitoring of blood glucose is crucial to prevent hypoglycemia.

Older adults may be at increased risk of hypoglycemia due to age-related changes in renal function, hepatic function, and counter-regulatory hormone responses. Lower starting doses and careful titration with frequent blood glucose monitoring are recommended. May also have impaired cognitive function or vision affecting self-administration.

• Humalog Tempo Pen is a prefilled pen designed for ease of use, but proper training on injection technique is crucial.
• Always check the insulin label carefully before each injection to ensure the correct type of insulin is being used.
• Insulin lispro should be clear and colorless; do not use if it appears cloudy, discolored, or contains particles.
• Rotate injection sites within the same region (e.g., abdomen) to minimize the risk of lipodystrophy (fat accumulation or atrophy at injection sites).
• Never reuse or share needles or insulin pens.
• Store unopened pens in the refrigerator (2°C to 8°C). Once opened, store at room temperature (below 30°C) and use within 28 days. Do not freeze.

• Other rapid-acting insulins: Insulin aspart (Novolog, Fiasp), Insulin glulisine (Apidra)
• Short-acting insulins: Regular human insulin (Humulin R, Novolin R)
• Intermediate-acting insulins: NPH human insulin (Humulin N, Novolin N)
• Long-acting insulins: Insulin glargine (Lantus, Toujeo, Basaglar), Insulin detemir (Levemir), Insulin degludec (Tresiba)
• Oral antidiabetic agents (for Type 2 Diabetes): Metformin, Sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors, GLP-1 receptor agonists, Thiazolidinediones, Alpha-glucosidase inhibitors, Meglitinides.

If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it occurred.