Temovate .05% Emollient Cream 60gm

Clobetasol propionate is a super high-potency topical corticosteroid. It induces phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. It exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties.

Urgent Side Effects: Seek Medical Help Right Away

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of high blood sugar, including:
+ Confusion
+ Feeling sleepy
+ Unusual thirst or hunger
+ Passing urine more often
+ Flushing
+ Fast breathing
+ Breath that smells like fruit
Signs of Cushing's syndrome, such as:
+ Weight gain in the upper back or belly
+ Moon face
+ Severe headache
+ Slow healing
Signs of a weak adrenal gland, including:
+ Severe upset stomach or vomiting
+ Severe dizziness or passing out
+ Muscle weakness
+ Feeling very tired
+ Mood changes
+ Decreased appetite
+ Weight loss
Skin changes, such as:
+ Pimples
+ Stretch marks
+ Slow healing
+ Hair growth
Irritation at the site of application
Thinning of the skin
Changes in eyesight, eye pain, or severe eye irritation

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms, contact your doctor for advice:

Burning or stinging
Dry skin
* Redness

This is not an exhaustive list of possible side effects. If you have questions or concerns, don't hesitate to reach out to your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you have thinning skin at the site where you will be applying this medication.
* If there is an active infection at the site where this medication will be used.

This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. Additionally, share any health problems you have to ensure safe use of this medication.

To guarantee your safety, do not start, stop, or adjust the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication with all your other medications and health conditions.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.

This medication is not intended to treat diaper rash, acne, rosacea, or rashes around the mouth. When applying it to a large area of skin or near open wounds, exercise caution and consult your doctor.

Before using any other medications or products on your skin, including soaps, discuss them with your doctor. Avoid applying this medication to cuts, scrapes, or damaged skin. Do not use this medication for an extended period beyond what your doctor has prescribed.

If this medication is accidentally swallowed, it can be harmful, so immediately contact a doctor or a poison control center. Long-term use of this medication may increase the risk of developing cataracts or glaucoma; therefore, consult your doctor about this potential risk.

This medication may not be suitable for children of all ages, so it is crucial to consult your doctor before administering it to a child. When using this medication in children, caution is advised, as they may have a higher risk of experiencing certain side effects. In some cases, this medication can affect growth in children and teenagers, making regular growth checks necessary. Discuss this with your doctor.

If you are breastfeeding, avoid applying this medication directly to the nipple or the surrounding area. If you are pregnant, plan to become pregnant, or are breastfeeding, inform your doctor, as you will need to discuss the potential benefits and risks to both you and your baby.

• Worsening of skin condition
• Signs of skin infection (e.g., pus, increased redness, warmth)
• Severe burning, stinging, or itching at application site
• Skin thinning, easy bruising, stretch marks (striae)
• Unusual hair growth
• Acne-like eruptions
• Signs of systemic absorption (e.g., weight gain, moon face, fatigue, weakness, mood changes - rare with appropriate topical use)

Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid large areas, prolonged use, or occlusive dressings.

Use with caution. It is not known whether topical clobetasol is excreted in human milk. Systemic absorption is minimal, but caution is advised. Avoid applying to areas that may come into contact with the infant's mouth (e.g., breast).

Not recommended for children under 12 years of age due to a higher risk of systemic absorption and HPA axis suppression (Cushing's syndrome, growth retardation). If use is unavoidable, limit to the smallest amount for the shortest duration possible and monitor closely for adverse effects.

No specific dose adjustments are required. However, elderly patients may have thinner, more fragile skin, increasing the risk of local adverse effects such as skin atrophy, purpura, and telangiectasias. Monitor closely.

• Clobetasol propionate is one of the most potent topical corticosteroids available. Its use should be reserved for severe, recalcitrant dermatoses.
• Strictly adhere to the recommended treatment duration (typically 2 weeks) and maximum weekly dosage (50g) to minimize the risk of HPA axis suppression and local skin adverse effects.
• Avoid use on the face, groin, axillae, or under occlusive dressings unless specifically directed by a dermatologist, due to increased risk of skin atrophy, striae, and systemic absorption.
• Patients should be educated on proper application technique (thin layer, gentle rubbing) and the importance of not exceeding prescribed amounts or duration.
• Consider tapering the frequency of application or switching to a lower-potency corticosteroid for maintenance therapy or if prolonged treatment is necessary to prevent rebound flares.

• Other topical corticosteroids of lower potency (e.g., fluocinonide, betamethasone, triamcinolone, hydrocortisone)
• Topical calcineurin inhibitors (e.g., tacrolimus, pimecrolimus) for steroid-sparing effect, especially on sensitive areas like the face.
• Vitamin D analogs (e.g., calcipotriene) for psoriasis.
• Topical retinoids (e.g., tazarotene) for psoriasis.
• Emollients and moisturizers for barrier repair and symptom relief.
• Systemic therapies (e.g., methotrexate, cyclosporine, biologics) for severe, widespread, or refractory dermatoses.

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist. If you have any questions or concerns about this medication, don't hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the medication taken, the amount, and the time it occurred.