Viibryd 40mg Tablets

Vilazodone is an antidepressant that acts as a selective serotonin reuptake inhibitor (SSRI) and a 5-HT1A receptor partial agonist. The combination of these two activities is thought to contribute to its antidepressant effects.

Urgent Side Effects: Seek Medical Help Immediately

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention right away:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of low sodium levels, including:
+ Headache
+ Trouble focusing
+ Memory problems
+ Feeling confused
+ Weakness
+ Seizures
+ Changes in balance
Signs of bleeding, such as:
+ Vomiting or coughing up blood
+ Vomit that resembles coffee grounds
+ Blood in the urine
+ Black, red, or tarry stools
+ Bleeding from the gums
+ Abnormal vaginal bleeding
+ Unexplained bruises or bruises that enlarge
+ Uncontrollable bleeding
Seizures
Sex-related problems, including:
+ Decreased interest in sex
+ Difficulty having an orgasm
+ Ejaculation problems
+ Trouble getting or maintaining an erection
Serotonin syndrome, a potentially life-threatening condition, which may be more likely to occur if you are taking certain other medications. Seek medical help immediately if you experience:
+ Agitation
+ Changes in balance
+ Confusion
+ Hallucinations
+ Fever
+ Fast or abnormal heartbeat
+ Flushing
+ Muscle twitching or stiffness
+ Seizures
+ Shivering or shaking
+ Excessive sweating
+ Severe diarrhea
+ Upset stomach
+ Vomiting
+ Severe headache

Other Possible Side Effects

Most people do not experience severe side effects, and some may only have minor side effects. However, if you notice any of the following side effects or any other unusual symptoms, contact your doctor or seek medical attention:

Trouble sleeping
Diarrhea
Stomach pain
Upset stomach
Vomiting
Dry mouth
Dizziness
Headache
* Feeling sleepy

Reporting Side Effects

If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced.
If you have been diagnosed with glaucoma.
If you are currently taking or have recently taken certain medications, including:
+ Linezolid or methylene blue.
+ Certain antidepressants or medications for Parkinson's disease within the last 14 days, such as isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline, as this may increase the risk of very high blood pressure.

Please note that this is not an exhaustive list of all potential interactions. To ensure your safety, it is crucial to discuss all of your:

Prescription and over-the-counter (OTC) medications.
Natural products.
Vitamins.
* Health problems.

with your doctor and pharmacist. They will help determine whether it is safe for you to take this medication in combination with your other medications and health conditions. Never start, stop, or adjust the dosage of any medication without first consulting your doctor.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Before engaging in activities that require alertness, such as driving, wait until you understand how this drug affects you. Additionally, avoid consuming alcohol while taking this medication.

Prior to using marijuana, other cannabis products, or prescription and over-the-counter (OTC) medications that may cause drowsiness, consult with your doctor. It may take several weeks to experience the full effects of this medication.

Do not abruptly stop taking this medication without consulting your doctor, as this may increase your risk of side effects. If you need to discontinue this medication, your doctor will instruct you on how to gradually stop taking it.

This medication may increase the risk of bleeding, which can be life-threatening in some cases. Discuss this risk with your doctor. Certain individuals may be more prone to eye problems while taking this medication. Your doctor may recommend an eye exam to assess your risk. Immediately contact your doctor if you experience eye pain, changes in vision, or swelling and redness in or around the eye.

Low blood sodium levels (hyponatremia) can occur with this medication, and in severe cases, this can be fatal. Discuss this risk with your doctor. If you are 65 years or older, use this medication with caution, as you may be more susceptible to side effects.

If you are pregnant, planning to become pregnant, or may be pregnant, inform your doctor. You will need to discuss the benefits and risks of taking this medication during pregnancy, as it may increase the risk of bleeding after delivery and cause health problems in the newborn, particularly if taken during the third trimester.

If you are breastfeeding, inform your doctor to discuss any potential risks to your baby.

• Monoamine Oxidase Inhibitors (MAOIs) (e.g., phenelzine, selegiline, linezolid, methylene blue) - risk of serotonin syndrome.
• Pimozide (risk of QT prolongation, though not a direct interaction with vilazodone, generally avoided with drugs affecting serotonin).

• Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir) - may increase vilazodone exposure; consider dose reduction.
• Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin) - may decrease vilazodone exposure; consider dose increase.
• Strong CYP2C19 inhibitors (e.g., omeprazole, fluoxetine) - may increase vilazodone exposure; consider dose reduction.
• Serotonergic drugs (e.g., other SSRIs, SNRIs, triptans, fentanyl, lithium, tramadol, St. John's Wort, buspirone) - increased risk of serotonin syndrome.
• Drugs that impair metabolism of serotonin (e.g., dextromethorphan, meperidine) - increased risk of serotonin syndrome.
• Anticoagulants/Antiplatelets (e.g., warfarin, aspirin, NSAIDs) - increased risk of bleeding due to SSRI effect on platelet aggregation.

• Worsening depression
• Suicidal thoughts or attempts
• Unusual changes in behavior (e.g., agitation, irritability, anxiety, panic attacks, insomnia, aggression, impulsivity, akathisia, hypomania, mania)
• Symptoms of Serotonin Syndrome (e.g., mental status changes, autonomic instability, neuromuscular abnormalities, gastrointestinal symptoms)
• Abnormal bleeding or bruising
• Seizures
• Hyponatremia symptoms (e.g., headache, difficulty concentrating, memory impairment, confusion, weakness, unsteadiness, falls, severe and more acute symptoms include hallucinations, syncope, seizure, coma, respiratory arrest)

Use during pregnancy should only be considered if the potential benefit justifies the potential risk to the fetus. Neonates exposed to SSRIs/SNRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. These complications can arise immediately upon delivery.

Vilazodone is excreted into breast milk. The decision to breastfeed should consider the developmental and health benefits of breastfeeding, the mother’s clinical need for vilazodone, and any potential adverse effects on the breastfed infant from vilazodone or from the underlying maternal condition.

Safety and effectiveness have not been established in pediatric patients for Major Depressive Disorder. Antidepressants increase the risk of suicidal thoughts and behavior in children, adolescents, and young adults.

No overall differences in safety or effectiveness were observed between elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out. Elderly patients may be at increased risk for hyponatremia and falls. Use with caution and monitor closely.

• Vilazodone MUST be taken with food. Taking it without food significantly reduces its absorption and effectiveness, leading to treatment failure.
• Titration is crucial: Start with 10 mg for 7 days, then increase to 20 mg. If needed, increase to 40 mg after another 7 days. This helps minimize gastrointestinal side effects.
• Common side effects include nausea, diarrhea, insomnia, and vomiting, especially during the initial titration phase. Taking with a substantial meal can help mitigate GI upset.
• As with other serotonergic antidepressants, monitor for serotonin syndrome, especially when co-administered with other serotonergic agents.
• Vilazodone has a low risk of weight gain and sexual dysfunction compared to some other antidepressants, which can be a benefit for some patients.
• Discontinuation syndrome can occur if stopped abruptly; taper dose gradually under medical supervision.

• SSRIs (e.g., escitalopram, sertraline, fluoxetine)
• SNRIs (e.g., venlafaxine, duloxetine)
• Atypical antidepressants (e.g., bupropion, mirtazapine)
• Other SPARI (e.g., vortioxetine)
• Tricyclic Antidepressants (TCAs)
• Monoamine Oxidase Inhibitors (MAOIs)

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure your safety, never share your medication with others or take someone else's medication. This medication is accompanied by a Medication Guide, which is a crucial patient fact sheet. Please read it carefully and review it again whenever you receive a refill. If you have any questions or concerns about this medication, we encourage you to discuss them with your doctor, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the substance taken, the amount, and the time it occurred.