Triamcinolone 0.1% Lotion 60ml
It is used to treat skin rashes and other skin irritation.
Drug Class
Topical Corticosteroid
Pharmacologic Class
Glucocorticoid
Pregnancy Category
Category C
FDA Approved
Aug 1961
DEA Schedule
Not Controlled
Overview
What is this medicine?
Triamcinolone lotion is a medicine applied to the skin to reduce redness, swelling, and itching caused by various skin conditions like eczema or psoriasis. It's a type of steroid that helps calm down your skin's immune response.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. Use this medication only on your skin, as directed. Avoid getting it in your mouth, nose, or eyes, as it may cause burning.
Continue using the medication as instructed, even if your symptoms improve. Before and after applying the medication, wash your hands thoroughly. However, if you're treating a skin condition on your hand, do not wash your hand after application.
Prepare the affected area by cleaning it before use and drying it well. Apply a thin layer of the medication to the affected skin and gently rub it in. Unless directed by your doctor, do not apply the medication to your face, underarms, or groin area.
Avoid using bandages, dressings, or tight-fitting diapers or plastic pants on the treated area, as this may increase the amount of medication absorbed into your body. Do not use this medication to treat diaper rash, and avoid applying it to cuts, scrapes, or damaged skin. Before use, shake the medication well.
Storage and Disposal
Store the medication at room temperature, avoiding freezing. Keep all medications in a safe place, out of the reach of children and pets. Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposing of medications, consult your pharmacist, who may be aware of drug take-back programs in your area.
Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not apply two doses at the same time or use extra doses to make up for a missed one.
To use this medication correctly, follow your doctor's instructions and read all the information provided. Use this medication only on your skin, as directed. Avoid getting it in your mouth, nose, or eyes, as it may cause burning.
Continue using the medication as instructed, even if your symptoms improve. Before and after applying the medication, wash your hands thoroughly. However, if you're treating a skin condition on your hand, do not wash your hand after application.
Prepare the affected area by cleaning it before use and drying it well. Apply a thin layer of the medication to the affected skin and gently rub it in. Unless directed by your doctor, do not apply the medication to your face, underarms, or groin area.
Avoid using bandages, dressings, or tight-fitting diapers or plastic pants on the treated area, as this may increase the amount of medication absorbed into your body. Do not use this medication to treat diaper rash, and avoid applying it to cuts, scrapes, or damaged skin. Before use, shake the medication well.
Storage and Disposal
Store the medication at room temperature, avoiding freezing. Keep all medications in a safe place, out of the reach of children and pets. Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposing of medications, consult your pharmacist, who may be aware of drug take-back programs in your area.
Missed Dose
If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not apply two doses at the same time or use extra doses to make up for a missed one.
Lifestyle & Tips
- Wash your hands before and after applying the lotion.
- Apply a thin layer of the lotion to the affected skin area and rub it in gently until it disappears.
- Do not use more than prescribed or apply to larger areas than instructed.
- Avoid applying the lotion to your eyes, mouth, or inside your nose.
- Do not cover the treated area with bandages or other occlusive dressings unless specifically instructed by your doctor, as this can increase absorption and side effects.
- Do not use for longer than prescribed, especially on the face, groin, or armpits, or in children.
- If you miss a dose, apply it as soon as you remember, unless it's almost time for your next dose. Do not double the dose.
- Keep out of reach of children.
Available Forms & Alternatives
Available Strengths:
- Triamcinolone 0.5% Cream 15gm
- Triamcinolone 0.5% Oint 15gm
- Triamcinolone 0.025% Ointment 15gm
- Triamcinolone 0.025% Ointment 80gm
- Triamcinolone 0.025% Cream 15gm
- Triamcinolone 0.1% Cream 30gm
- Triamcinolone 0.1% Cream 15gm
- Triamcinolone 0.025% Cream 454gm
- Triamcinolone 0.1% Ointment 15gm
- Triamcinolone 0.1% Cream 80gm
- Triamcinolone 0.1% Ointment 80gm
- Triamcinolone 0.1% Ointment 454gm
- Triamcinolone 0.1% Cream 454gm
- Triamcinolone 0.025% Ointment 454gm
- Triamcinolone 0.1% Ointment 15gm
- Triamcinolone 0.025% Cream 80gm
- Triamcinolone 0.1% Ointment 80gm
- Triamcinolone Topical Spray 100gm
- Triamcinolone Topical Spray 63gm
- Triamcinolone 0.1% Lotion 60ml
- Triamcinolone 0.1% Ointment 15gm
- Triamcinolone 0.1% Ointment 30gm
- Triamcinolone 55mcg Nasalsp (120)
- Triamcinolone Ace 40mg/ml, 1ml
- Triamcinolone Topical Spray 63gm
- Triamcinolone Topical Spray 100gm
- Triamcinolone Ace 40mg/ml Inj, 10ml
- Triamcinolone Ace 0.05% Oint 430gm
- Triamcinolone Ace 40mg/ml, 5ml
- Triamcin Ace 40mg/ml Inj, 10ml
- Triamcinolone 0.1% Lotion 60ml
- Triamcinolone 0.025% Lotion 60ml
- Triamcinolone 400mg/10ml Inj, 10ml
- Triamcinolone 0.1% Ointment 454gm
Dosing & Administration
Adult Dosing
Standard Dose:
Apply a thin film to the affected area two to four times daily, depending on severity.
Condition-Specific Dosing:
psoriasis:
Apply a thin film to the affected area two to four times daily.
eczema:
Apply a thin film to the affected area two to four times daily.
Pediatric Dosing
Neonatal:
Not established
Infant:
Apply a thin film to the affected area two to four times daily. Use with caution; increased risk of systemic absorption due to higher surface area to body weight ratio and immature skin barrier. Avoid occlusive dressings.
Child:
Apply a thin film to the affected area two to four times daily. Use with caution; increased risk of systemic absorption. Avoid occlusive dressings.
Adolescent:
Apply a thin film to the affected area two to four times daily.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment typically needed for topical application.
Moderate:
No adjustment typically needed for topical application.
Severe:
No adjustment typically needed for topical application.
Dialysis:
No specific considerations for topical application.
Hepatic Impairment:
Mild:
No adjustment typically needed for topical application.
Moderate:
No adjustment typically needed for topical application.
Severe:
No adjustment typically needed for topical application.
Pharmacology
Mechanism of Action
Triamcinolone acetonide is a synthetic corticosteroid that possesses anti-inflammatory, antipruritic, and vasoconstrictive properties. It acts by inducing phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption (typically <1%) through intact skin; increased with inflammation, skin damage, occlusion, or application to large surface areas.
Tmax:
Not applicable for topical use; systemic absorption is minimal and variable.
FoodEffect:
Not applicable for topical use.
Distribution:
Vd:
Not available (minimal systemic distribution)
ProteinBinding:
Not available (minimal systemic distribution)
CnssPenetration:
Limited (minimal systemic absorption)
Elimination:
HalfLife:
Not available (minimal systemic absorption)
Clearance:
Not available (minimal systemic absorption)
ExcretionRoute:
Renal (if systemically absorbed)
Unchanged:
Not available
Pharmacodynamics
OnsetOfAction:
Within hours to days for symptomatic relief.
PeakEffect:
Days to weeks of consistent application.
DurationOfAction:
Varies with severity of condition and frequency of application.
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention immediately:
Signs of an allergic reaction: rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat
Signs of high blood sugar: confusion, feeling sleepy, unusual thirst or hunger, frequent urination, flushing, rapid breathing, or fruity-smelling breath
Signs of a weak adrenal gland: severe nausea or vomiting, severe dizziness or fainting, muscle weakness, extreme fatigue, mood changes, decreased appetite, or weight loss
Signs of Cushing's syndrome: weight gain in the upper back or abdomen, moon face, severe headache, or slow wound healing
Irritation at the application site
Skin changes: acne, stretch marks, slow healing, or excessive hair growth
Changes in skin color
Thinning of the skin
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people experience no side effects or only mild ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Burning sensation
Itching
* Dry skin
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention immediately:
Signs of an allergic reaction: rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat
Signs of high blood sugar: confusion, feeling sleepy, unusual thirst or hunger, frequent urination, flushing, rapid breathing, or fruity-smelling breath
Signs of a weak adrenal gland: severe nausea or vomiting, severe dizziness or fainting, muscle weakness, extreme fatigue, mood changes, decreased appetite, or weight loss
Signs of Cushing's syndrome: weight gain in the upper back or abdomen, moon face, severe headache, or slow wound healing
Irritation at the application site
Skin changes: acne, stretch marks, slow healing, or excessive hair growth
Changes in skin color
Thinning of the skin
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people experience no side effects or only mild ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Burning sensation
Itching
* Dry skin
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Increased irritation, burning, or stinging after application.
- Signs of skin infection (e.g., pus, spreading redness, fever).
- Skin thinning, easy bruising, or stretch marks appearing on the treated area.
- Acne-like breakouts or increased hair growth on the treated area.
- Any signs of systemic side effects like unusual weight gain, swelling in the face, or extreme tiredness (rare, but possible with prolonged or extensive use).
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Be sure to describe the allergic reaction you experienced, including the symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health issues to your doctor and pharmacist.
* Any health problems you have, as this information will help your doctor determine if it is safe for you to take this medication.
Remember, you must verify that it is safe to take this medication with all your other medications and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Be sure to describe the allergic reaction you experienced, including the symptoms that occurred.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is not an exhaustive list, and it is crucial to disclose all your medications and health issues to your doctor and pharmacist.
* Any health problems you have, as this information will help your doctor determine if it is safe for you to take this medication.
Remember, you must verify that it is safe to take this medication with all your other medications and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Adhere to the prescribed duration of treatment and do not use this drug for an extended period beyond what your doctor has recommended.
Before using any other medications or products on your skin, including soaps, consult with your doctor to ensure safe and effective treatment. Exercise caution when applying this medication to a large area of skin, and discuss this with your doctor if necessary.
Using this medication too frequently can exacerbate your skin condition. If the patient is a child, use this medication with caution, as the risk of certain side effects may be higher in children. In some cases, this drug may affect growth in children and teenagers, and regular growth checks may be necessary. Consult with your doctor to discuss this potential risk.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. It is crucial to weigh the benefits and risks of using this medication during these situations to ensure the best possible outcome for both you and your baby.
Before using any other medications or products on your skin, including soaps, consult with your doctor to ensure safe and effective treatment. Exercise caution when applying this medication to a large area of skin, and discuss this with your doctor if necessary.
Using this medication too frequently can exacerbate your skin condition. If the patient is a child, use this medication with caution, as the risk of certain side effects may be higher in children. In some cases, this drug may affect growth in children and teenagers, and regular growth checks may be necessary. Consult with your doctor to discuss this potential risk.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. It is crucial to weigh the benefits and risks of using this medication during these situations to ensure the best possible outcome for both you and your baby.
Overdose Information
Overdose Symptoms:
- Prolonged or excessive use of topical corticosteroids can lead to systemic effects due to absorption, including suppression of the hypothalamic-pituitary-adrenal (HPA) axis, Cushing's syndrome, hyperglycemia, and glucosuria. Symptoms may include: unusual fatigue, weakness, weight gain (especially in the face and trunk), increased thirst, increased urination, and high blood sugar.
What to Do:
Discontinue use gradually under medical supervision. Symptomatic and supportive treatment. If HPA axis suppression is confirmed, a gradual withdrawal of the drug or substitution with a less potent corticosteroid may be necessary. Call 1-800-222-1222 (Poison Control) for advice if accidental ingestion or significant overdose is suspected.
Drug Interactions
Monitoring
Baseline Monitoring
Skin condition assessment
Rationale: To establish baseline severity of dermatosis and identify areas for application.
Timing: Prior to initiation of therapy.
Routine Monitoring
Efficacy (reduction in inflammation, pruritus)
Frequency: Regularly, at follow-up visits (e.g., weekly to monthly depending on condition).
Target: Significant improvement in symptoms.
Action Threshold: Lack of improvement or worsening symptoms may indicate need for re-evaluation or alternative therapy.
Local skin adverse effects (e.g., atrophy, striae, telangiectasias, folliculitis, perioral dermatitis)
Frequency: At each follow-up visit and patient self-monitoring.
Target: Absence of new or worsening adverse effects.
Action Threshold: Development of significant local adverse effects warrants reduction in frequency, discontinuation, or change to a lower potency corticosteroid.
Signs of systemic absorption (e.g., Cushing's syndrome, hyperglycemia, HPA axis suppression)
Frequency: Periodically, especially with prolonged use, large surface areas, or occlusive dressings.
Target: Absence of systemic signs.
Action Threshold: If suspected, consider HPA axis testing (e.g., ACTH stimulation test) and gradual withdrawal of therapy.
Symptom Monitoring
- Worsening skin redness or irritation
- Burning or stinging sensation at application site
- Skin thinning or atrophy
- Stretch marks (striae)
- Spider veins (telangiectasias)
- Acne-like eruptions (folliculitis)
- Increased hair growth at application site
- Changes in skin color (hypopigmentation)
- Signs of infection (pus, fever)
- Unusual fatigue or weakness (potential HPA axis suppression)
- Increased thirst or urination (potential hyperglycemia)
Special Patient Groups
Pregnancy
Use during pregnancy should be considered only if the potential benefit justifies the potential risk to the fetus. Category C. Animal studies have shown corticosteroids to be teratogenic.
Trimester-Specific Risks:
First Trimester:
Potential for teratogenicity, though systemic absorption from topical use is low.
Second Trimester:
Generally considered safer than first trimester, but still use with caution.
Third Trimester:
No specific risks identified beyond general corticosteroid effects; however, avoid large areas or prolonged use.
Lactation
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Use with caution. Avoid applying to the breast area to prevent infant ingestion.
Infant Risk:
Low risk with limited, short-term use on small areas. Potential for growth suppression or other adverse effects if significant systemic absorption occurs in the infant via breast milk or direct skin contact.
Pediatric Use
Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients due to a larger skin surface area to body weight ratio. Use the least potent corticosteroid for the shortest duration possible. Avoid occlusive dressings. Monitor for signs of systemic absorption and growth retardation.
Geriatric Use
No specific dosage adjustments are generally needed. However, elderly patients may have thinner skin, which could potentially increase systemic absorption. Use with caution and monitor for adverse effects.
Clinical Information
Clinical Pearls
- Triamcinolone 0.1% lotion is a medium-potency topical corticosteroid, suitable for various inflammatory dermatoses.
- Lotion formulations are often preferred for hairy areas or weeping lesions due to their lighter consistency.
- Advise patients to apply a very thin layer; a little goes a long way.
- Educate patients on the importance of not using occlusive dressings unless specifically instructed by a healthcare provider, especially in children, to prevent increased systemic absorption.
- Long-term use, especially on the face, intertriginous areas (skin folds), or in children, increases the risk of local side effects (e.g., skin atrophy, telangiectasias, striae) and systemic absorption.
- If no improvement is seen after 2-4 weeks, re-evaluate the diagnosis and treatment plan.
Alternative Therapies
- Other topical corticosteroids (e.g., hydrocortisone, fluocinolone, clobetasol, betamethasone) of varying potencies.
- Topical calcineurin inhibitors (e.g., tacrolimus, pimecrolimus) for eczema, especially on sensitive areas.
- Topical phosphodiesterase-4 (PDE4) inhibitors (e.g., crisaborole) for eczema.
- Emollients and moisturizers for barrier repair.
- Systemic therapies (e.g., oral corticosteroids, biologics) for severe, widespread conditions.
Cost & Coverage
Average Cost:
$15 - $50 per 60ml lotion
Generic Available:
Yes
Insurance Coverage:
Tier 1 or 2 (Generic)
General Drug Facts
If your symptoms or health condition do not improve or worsen over time, it is essential to contact your doctor for further evaluation and guidance.
To ensure your safety and the effectiveness of your treatment, never share your medication with others or take medication prescribed to someone else.
It's possible that some medications come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information.
If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider for guidance and support.
In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide as much information as possible about the overdose, including the name of the medication taken, the amount, and the time it occurred.
To ensure your safety and the effectiveness of your treatment, never share your medication with others or take medication prescribed to someone else.
It's possible that some medications come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information.
If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider for guidance and support.
In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide as much information as possible about the overdose, including the name of the medication taken, the amount, and the time it occurred.