Prevident 5000 Dry Mouthmint Paste
This supplement is used to prevent cavities.
Drug Class
Dental caries prophylactic
Pharmacologic Class
Fluoride; Remineralizing agent
Pregnancy Category
Category B
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
This is a special toothpaste with a high concentration of fluoride. It helps to strengthen your tooth enamel, make it more resistant to cavities, and can help reverse early signs of tooth decay. It's especially helpful for people with dry mouth or a high risk of cavities.
How to Use This Medicine
Taking Your Medication Correctly
To use this medication effectively, follow your doctor's instructions and read all accompanying information carefully. Unless your doctor advises otherwise, use this gel in place of your regular toothpaste.
To apply:
- Use a pea-sized amount of the gel.
- Brush your teeth thoroughly.
- Allow the gel to remain on your teeth for 1 minute before spitting it out.
- Do not swallow the gel.
- After using the gel, wait at least 30 minutes before eating, drinking, or rinsing your mouth.
Storing and Disposing of Your Medication
- Store the medication at room temperature.
- Keep all medications in a secure location, out of the reach of children and pets.
- Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you are unsure about the best disposal method, consult your pharmacist. Your area may have drug take-back programs available.
Managing Missed Doses
If you miss a dose, use it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Avoid using two doses at the same time or taking extra doses.
To use this medication effectively, follow your doctor's instructions and read all accompanying information carefully. Unless your doctor advises otherwise, use this gel in place of your regular toothpaste.
To apply:
- Use a pea-sized amount of the gel.
- Brush your teeth thoroughly.
- Allow the gel to remain on your teeth for 1 minute before spitting it out.
- Do not swallow the gel.
- After using the gel, wait at least 30 minutes before eating, drinking, or rinsing your mouth.
Storing and Disposing of Your Medication
- Store the medication at room temperature.
- Keep all medications in a secure location, out of the reach of children and pets.
- Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you are unsure about the best disposal method, consult your pharmacist. Your area may have drug take-back programs available.
Managing Missed Doses
If you miss a dose, use it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Avoid using two doses at the same time or taking extra doses.
Lifestyle & Tips
- Brush thoroughly once daily, preferably at bedtime.
- Spit out the paste after brushing; do not swallow.
- Do not rinse your mouth, eat, or drink for at least 30 minutes after brushing to allow the fluoride to work effectively.
- Maintain good overall oral hygiene, including regular flossing and dental check-ups.
- Limit sugary foods and drinks.
Available Forms & Alternatives
Available Strengths:
- Prevident Gel Mint 56.6gm
- Prevident 1.1% Gel Berry 56.6gm
- Prevident 5000plus Cream(spearmint)
- Prevident 5000 Plus Cream (fruit)
- Prevident 5000 Sensitive Paste Mint
- Prevident 5000 Dry Mouthmint Paste
- Prevident 5000 Enamel Mint Paste
- Prevident 5000 Bstr Plus Paste/mint
- Prevident 5000 Bst Plus Paste/fruit
- Prevident 0.2% Solution 473ml
Dosing & Administration
Adult Dosing
Standard Dose:
Apply a thin ribbon of paste to a toothbrush and brush thoroughly once daily, preferably at bedtime, for at least one minute. Spit out after use. Do not rinse, eat, or drink for 30 minutes after use.
Pediatric Dosing
Neonatal:
Not established
Infant:
Not established
Child:
Children 6-16 years: Apply a thin ribbon of paste to a toothbrush and brush thoroughly once daily, preferably at bedtime, for at least one minute. Supervise to ensure spitting out and to minimize swallowing. Do not rinse, eat, or drink for 30 minutes after use.
Adolescent:
Adolescents 16 years and older: Same as adult dosing.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Dialysis:
No specific considerations (minimal systemic absorption)
Hepatic Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Pharmacology
Mechanism of Action
Fluoride acts topically to promote remineralization of demineralized enamel, inhibit demineralization, and inhibit bacterial acid production. It incorporates into the enamel structure, forming fluorapatite, which is more resistant to acid dissolution than hydroxyapatite. It also has antibacterial effects against cariogenic bacteria.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption (primarily local action)
Tmax:
Not applicable (topical)
FoodEffect:
Not applicable (topical)
Distribution:
Vd:
Not applicable (primarily local action)
ProteinBinding:
Not applicable (primarily local action)
CnssPenetration:
No (minimal systemic absorption)
Elimination:
HalfLife:
Not applicable (primarily local action)
Clearance:
Not applicable (primarily local action)
ExcretionRoute:
Not applicable (primarily local action)
Unchanged:
Not applicable (primarily local action)
Pharmacodynamics
OnsetOfAction:
Immediate (local effect on enamel surface)
PeakEffect:
Continuous with regular use, cumulative effect on enamel strength
DurationOfAction:
Persistent effect on enamel structure, but requires ongoing application for sustained benefit
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Severe stomach upset or vomiting
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for advice:
Note: This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, don't hesitate to reach out to your doctor.
Reporting Side Effects
To report side effects, you can:
Call the FDA at 1-800-332-1088
Visit the FDA's MedWatch website at https://www.fda.gov/medwatch to report side effects online.
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Severe stomach upset or vomiting
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for advice:
Note: This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, don't hesitate to reach out to your doctor.
Reporting Side Effects
To report side effects, you can:
Call the FDA at 1-800-332-1088
Visit the FDA's MedWatch website at https://www.fda.gov/medwatch to report side effects online.
Seek Immediate Medical Attention If You Experience:
- Nausea, vomiting, or stomach pain (if swallowed in large amounts)
- Oral irritation or allergic reaction (rare)
- White or brown spots on teeth (signs of fluorosis, especially in children)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain health conditions, including:
+ Bone problems
+ Joint problems
+ Kidney problems
+ Ulcers
The level of fluoride in your drinking water, particularly if it is greater than or equal to 0.6 parts per million.
Additionally, to ensure safe treatment, it is crucial to disclose all of your:
Prescription and over-the-counter (OTC) medications
Natural products
Vitamins
Share this information with both your doctor and pharmacist to verify that it is safe to take this medication in conjunction with your other treatments and health conditions. Never start, stop, or modify the dosage of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain health conditions, including:
+ Bone problems
+ Joint problems
+ Kidney problems
+ Ulcers
The level of fluoride in your drinking water, particularly if it is greater than or equal to 0.6 parts per million.
Additionally, to ensure safe treatment, it is crucial to disclose all of your:
Prescription and over-the-counter (OTC) medications
Natural products
Vitamins
Share this information with both your doctor and pharmacist to verify that it is safe to take this medication in conjunction with your other treatments and health conditions. Never start, stop, or modify the dosage of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you notice any staining or spotting on your teeth, be sure to notify your dentist. Regular dental care is crucial, so schedule frequent dental check-ups to maintain good oral health.
In the event of accidental ingestion of a large amount of this medication, seek immediate medical attention by calling a doctor or poison control center. Note that different brands of this medication may be suitable for children of various ages, so it is crucial to consult with your doctor before administering this drug to a child.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby.
In the event of accidental ingestion of a large amount of this medication, seek immediate medical attention by calling a doctor or poison control center. Note that different brands of this medication may be suitable for children of various ages, so it is crucial to consult with your doctor before administering this drug to a child.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby.
Overdose Information
Overdose Symptoms:
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Salivation
- Headache
- Weakness
- In severe cases: muscle cramps, convulsions, cardiac arrhythmias, respiratory depression
What to Do:
If a large amount is swallowed, especially by a child, immediately seek emergency medical attention or call Poison Control at 1-800-222-1222. Induce vomiting if advised by Poison Control. Administer milk or calcium-containing liquids to bind fluoride.
Drug Interactions
Monitoring
Baseline Monitoring
Dental examination
Rationale: To assess baseline oral health and identify areas of concern for fluoride treatment.
Timing: Prior to initiation of therapy
Routine Monitoring
Oral hygiene compliance
Frequency: At each dental visit (typically every 6-12 months)
Target: Consistent daily use as directed
Action Threshold: Poor compliance may necessitate re-education or alternative strategies.
Signs of dental fluorosis
Frequency: At each dental visit, especially in children
Target: Absence of white flecks or brown stains on enamel
Action Threshold: Presence of fluorosis may indicate excessive fluoride intake and require adjustment of fluoride regimen.
Symptom Monitoring
- Oral irritation
- Nausea (if swallowed in large amounts)
- Stomach upset (if swallowed in large amounts)
- White flecks or brown stains on teeth (signs of fluorosis)
Special Patient Groups
Pregnancy
Topical fluoride is generally considered safe during pregnancy due to minimal systemic absorption. Consult with a healthcare provider.
Trimester-Specific Risks:
First Trimester:
Low risk
Second Trimester:
Low risk
Third Trimester:
Low risk
Lactation
Topical fluoride is considered safe during lactation due to minimal systemic absorption and negligible transfer into breast milk.
Infant Risk:
Low risk
Pediatric Use
Use in children under 6 years is generally not recommended due to the risk of dental fluorosis from accidental ingestion. For children 6-16 years, use under adult supervision to ensure spitting out and minimize swallowing. Dosing should be carefully monitored by a dentist or physician.
Geriatric Use
No specific dosage adjustments are needed. Generally safe and effective for older adults, especially those at high risk for root caries or dry mouth.
Clinical Information
Clinical Pearls
- This high-concentration fluoride paste is typically prescribed for patients at high risk of dental caries, including those with dry mouth, orthodontic appliances, radiation therapy to the head and neck, or a history of multiple cavities.
- Emphasize the 'spit, don't rinse' instruction to maximize fluoride retention on tooth surfaces.
- Advise patients to use this product at bedtime to allow the fluoride to work overnight without disruption from eating or drinking.
- For patients with severe dry mouth, the 'Dry Mouthmint' formulation may offer additional comfort and moisture.
- Regular dental check-ups are crucial to monitor effectiveness and detect any signs of fluorosis, especially in pediatric patients.
Alternative Therapies
- Xylitol-containing products (chewing gum, lozenges) for dry mouth and caries prevention
- Amorphous Calcium Phosphate (ACP) or Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) products for remineralization
- Chlorhexidine rinses (for bacterial control, short-term use)
- Dental sealants (for pit and fissure caries prevention)
Cost & Coverage
Average Cost:
$15 - $30 per 51g tube
Generic Available:
Yes
Insurance Coverage:
Often covered by dental insurance plans or eligible for FSA/HSA reimbursement.
General Drug Facts
If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more details. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek medical attention. When seeking help, be prepared to provide information about the medication taken, the amount, and the time it occurred.