One-Daily Multi Vitamins Tablets
WARNING: If your product has iron in it:Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep away from children. If this drug is taken by accident, call a doctor or poison control center right away. @ COMMON USES: It is used to help growth and good health.It may be given to you for other reasons. Talk with the doctor.
Drug Class
Nutritional Supplement; Vitamin Supplement
Pharmacologic Class
Vitamins; Minerals; Nutrients
Pregnancy Category
Not applicable (Dietary Supplement); generally Category A/B at recommended doses, higher doses of specific vitamins (e.g., Vitamin A, D) can be Category C/D/X.
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
One-Daily Multi Vitamins are dietary supplements that provide a broad range of essential vitamins and minerals your body needs to function properly. They are designed to fill nutritional gaps in your diet and support overall health, energy, and well-being.
How to Use This Medicine
Taking Your Medication Correctly
To get the most benefit from your medication, take it exactly as directed by your doctor. Carefully read all the information provided with your prescription, and follow the instructions closely.
Administration Instructions
You can take this medication with or without food. If it causes stomach upset, taking it with food may help.
For optimal absorption, take this medication at bedtime. If you have questions about the best time to take your medication, consult your doctor or pharmacist.
Extended-Release Products: Swallow the tablets whole; do not chew, break, or crush them.
Liquid Formulation: Measure the liquid dose accurately using the provided measuring device. If one is not included, ask your pharmacist for a suitable measuring device.
* Chewable Tablets: Chew the tablets thoroughly before swallowing.
Storage and Disposal
Store your medication at room temperature in a dry location, away from the bathroom. Protect it from heat and light. Keep all medications in a secure place, out of the reach of children and pets.
Missing a Dose
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or take extra doses to make up for the missed one.
To get the most benefit from your medication, take it exactly as directed by your doctor. Carefully read all the information provided with your prescription, and follow the instructions closely.
Administration Instructions
You can take this medication with or without food. If it causes stomach upset, taking it with food may help.
For optimal absorption, take this medication at bedtime. If you have questions about the best time to take your medication, consult your doctor or pharmacist.
Extended-Release Products: Swallow the tablets whole; do not chew, break, or crush them.
Liquid Formulation: Measure the liquid dose accurately using the provided measuring device. If one is not included, ask your pharmacist for a suitable measuring device.
* Chewable Tablets: Chew the tablets thoroughly before swallowing.
Storage and Disposal
Store your medication at room temperature in a dry location, away from the bathroom. Protect it from heat and light. Keep all medications in a secure place, out of the reach of children and pets.
Missing a Dose
If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or take extra doses to make up for the missed one.
Lifestyle & Tips
- Take with food to enhance absorption and reduce stomach upset.
- Do not exceed the recommended dose, as excessive intake of some vitamins can be harmful.
- Multi-vitamins are supplements, not substitutes for a balanced and healthy diet.
- Store in a cool, dry place, away from direct sunlight and out of reach of children.
- Inform your healthcare provider about all supplements you are taking, especially if you are on other medications or have underlying health conditions.
Available Forms & Alternatives
Dosing & Administration
Adult Dosing
Standard Dose:
One tablet orally once daily, preferably with a meal.
Dose Range:
1 - 1 mg
Condition-Specific Dosing:
general_health_maintenance:
One tablet daily
Pediatric Dosing
Neonatal:
Not established; specific infant/pediatric formulations are available.
Infant:
Not established; specific infant/pediatric formulations are available.
Child:
Not established; specific pediatric formulations are available; consult product label or healthcare provider.
Adolescent:
Typically one tablet orally once daily, similar to adult dosing, but consult product label for age-specific recommendations.
Dose Adjustments
Renal Impairment:
Mild:
Generally no specific adjustment for standard doses.
Moderate:
Generally no specific adjustment for standard doses; caution with high doses of fat-soluble vitamins (A, D, E, K) and water-soluble vitamins (e.g., Vitamin C, B vitamins) due to potential accumulation or altered metabolism.
Severe:
Use with caution; high doses of Vitamin A and D can accumulate. Consult a healthcare provider. Specific vitamin levels may need monitoring.
Dialysis:
Specific vitamin supplementation may be required for dialysis patients (e.g., water-soluble vitamins lost during dialysis); consult nephrologist.
Hepatic Impairment:
Mild:
Generally no specific adjustment for standard doses.
Moderate:
Generally no specific adjustment for standard doses; caution with high doses of fat-soluble vitamins (A, D, E, K) due to altered metabolism and storage.
Severe:
Use with caution; high doses of Vitamin A can be hepatotoxic. Consult a healthcare provider.
Pharmacology
Mechanism of Action
Vitamins are essential organic compounds that the body needs in small amounts for various metabolic processes. They act as coenzymes, antioxidants, hormones, and structural components, playing crucial roles in energy production, immune function, cell growth and repair, vision, bone health, and nervous system function. Multi-vitamins provide a broad spectrum of these essential nutrients to supplement dietary intake and prevent deficiencies.
Pharmacokinetics
Absorption:
Bioavailability:
Variable (depends on specific vitamin, formulation, presence of food, and individual factors). Water-soluble vitamins (B, C) are generally well-absorbed but not stored. Fat-soluble vitamins (A, D, E, K) require dietary fat for absorption and are stored in the body.
Tmax:
Variable (minutes to hours, depending on specific vitamin and formulation).
FoodEffect:
Absorption of fat-soluble vitamins is enhanced by food, especially fatty meals. Some water-soluble vitamins may also be better absorbed with food to minimize gastrointestinal upset.
Distribution:
Vd:
Variable (depends on specific vitamin; water-soluble vitamins distribute in body water, fat-soluble vitamins distribute into adipose tissue and liver).
ProteinBinding:
Variable (some vitamins, like Vitamin D, are highly protein-bound; others, like Vitamin C, are not).
CnssPenetration:
Limited for some, essential for others (e.g., B vitamins for neurological function).
Elimination:
HalfLife:
Variable (minutes to days/months, depending on specific vitamin; water-soluble vitamins have shorter half-lives and are readily excreted, fat-soluble vitamins have longer half-lives and can accumulate).
Clearance:
Variable (renal for water-soluble, biliary/fecal for fat-soluble).
ExcretionRoute:
Renal (water-soluble vitamins); Biliary/Fecal (fat-soluble vitamins).
Unchanged:
Variable (some water-soluble vitamins are excreted largely unchanged).
Pharmacodynamics
OnsetOfAction:
Not applicable for chronic supplementation; effects are cumulative and aimed at preventing or correcting long-term deficiencies.
PeakEffect:
Not applicable for chronic supplementation.
DurationOfAction:
Not applicable for chronic supplementation; effects are sustained with regular intake.
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Attention Immediately
Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical help right away:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Change in stool color to green
+ Stomach pain
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical help right away:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Change in stool color to green
+ Stomach pain
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Severe nausea or vomiting
- Diarrhea or severe constipation
- Unusual fatigue or weakness
- Headache or dizziness
- Skin rash, itching, or hives
- Yellowing of skin or eyes (jaundice)
- Bone or joint pain
- Hair loss
- Changes in vision
- Any signs of allergic reaction (swelling of face/tongue/throat, difficulty breathing)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following conditions to ensure safe treatment:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Describe the allergic reaction you experienced, such as symptoms and signs.
Certain types of anemia, including pernicious anemia, which is characterized by a lack of vitamin B12 in the body.
If you are taking levodopa, as it may interact with this medication.
If you are taking mineral oil, as it may affect the absorption of this medication.
* If your product contains iron:
+ If you have an excess of iron in your body (iron overload).
+ If you have hemolytic anemia, a condition where red blood cells are destroyed faster than they can be made.
This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. They will help you determine if it is safe to take this medication with your existing treatments and health conditions. Never start, stop, or change the dose of any medication without consulting your doctor first.
It is essential to inform your doctor about the following conditions to ensure safe treatment:
Any allergies you have to this medication, its components, or other substances, including foods and drugs. Describe the allergic reaction you experienced, such as symptoms and signs.
Certain types of anemia, including pernicious anemia, which is characterized by a lack of vitamin B12 in the body.
If you are taking levodopa, as it may interact with this medication.
If you are taking mineral oil, as it may affect the absorption of this medication.
* If your product contains iron:
+ If you have an excess of iron in your body (iron overload).
+ If you have hemolytic anemia, a condition where red blood cells are destroyed faster than they can be made.
This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. They will help you determine if it is safe to take this medication with your existing treatments and health conditions. Never start, stop, or change the dose of any medication without consulting your doctor first.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This drug may interfere with certain laboratory tests, so be sure to notify all your healthcare providers and laboratory personnel that you are taking it.
If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Similarly, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.
When administering this medication to children, note that different brands may be suitable for different age groups. Therefore, it is crucial to consult with your doctor before giving this medication to a child to ensure you are using the correct brand and dosage.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of taking this medication to you and your baby.
If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Similarly, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.
When administering this medication to children, note that different brands may be suitable for different age groups. Therefore, it is crucial to consult with your doctor before giving this medication to a child to ensure you are using the correct brand and dosage.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of taking this medication to you and your baby.
Overdose Information
Overdose Symptoms:
- Nausea, vomiting, diarrhea, abdominal pain
- Headache, dizziness, blurred vision
- Fatigue, muscle weakness
- Skin changes (dryness, peeling, yellowing)
- Bone pain, joint swelling
- Hair loss
- Liver damage (from excessive Vitamin A)
- Kidney stones, hypercalcemia (from excessive Vitamin D or Calcium)
- Increased bleeding risk (from excessive Vitamin E)
- Nerve damage (from excessive Vitamin B6)
What to Do:
If you suspect an overdose, seek immediate medical attention or call a poison control center (1-800-222-1222 in the U.S.). Bring the product packaging with you. Treatment is supportive and may involve gastric decontamination, hydration, and monitoring of vital signs and specific vitamin/mineral levels.
Drug Interactions
Major Interactions
- Warfarin (Coumadin) + Vitamin K: Vitamin K can reduce the anticoagulant effect of warfarin.
- Tetracyclines (e.g., doxycycline, minocycline) + Iron/Calcium/Magnesium/Zinc: These minerals can chelate tetracyclines, reducing their absorption.
- Fluoroquinolones (e.g., ciprofloxacin, levofloxacin) + Iron/Calcium/Magnesium/Zinc: These minerals can chelate fluoroquinolones, reducing their absorption.
- Levothyroxine (Synthroid) + Calcium/Iron: Calcium and iron can impair levothyroxine absorption.
Moderate Interactions
- Anticonvulsants (e.g., phenytoin, phenobarbital) + Folic Acid/Vitamin D: May alter metabolism or increase requirements for these vitamins.
- Diuretics (e.g., thiazides, loop diuretics) + Calcium/Potassium/Magnesium: May alter excretion of these minerals.
- Bile Acid Sequestrants (e.g., cholestyramine) + Fat-soluble vitamins (A, D, E, K): May reduce absorption of fat-soluble vitamins.
- Orlistat (Xenical) + Fat-soluble vitamins (A, D, E, K): May reduce absorption of fat-soluble vitamins.
- Proton Pump Inhibitors (e.g., omeprazole) + Vitamin B12/Magnesium: May reduce absorption of Vitamin B12 and magnesium.
- Metformin + Vitamin B12: May reduce Vitamin B12 absorption.
- Anticoagulants (e.g., aspirin, clopidogrel) + Vitamin E (high doses): May increase risk of bleeding.
Minor Interactions
- Alcohol + B vitamins: Chronic alcohol consumption can deplete B vitamins.
- Caffeine + Calcium: May slightly increase calcium excretion.
Monitoring
Baseline Monitoring
Dietary intake assessment
Rationale: To determine if supplementation is truly needed or if dietary changes are sufficient.
Timing: Prior to starting supplementation, especially if specific deficiencies are suspected.
Baseline blood tests (e.g., CBC, metabolic panel, specific vitamin levels like Vitamin D, B12, Folate)
Rationale: If there are clinical signs of deficiency or specific risk factors, to identify existing deficiencies.
Timing: As clinically indicated, before starting supplementation.
Routine Monitoring
General well-being and symptom assessment
Frequency: Ongoing, at routine check-ups
Target: Improved energy, reduced fatigue, absence of deficiency symptoms
Action Threshold: Development of new symptoms, worsening of existing symptoms, or signs of toxicity (e.g., nausea, vomiting, headache, skin changes).
Symptom Monitoring
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Headache
- Dizziness
- Skin rash or itching
- Unusual fatigue or weakness
- Changes in urine color (e.g., bright yellow from riboflavin)
- Signs of hypervitaminosis (e.g., bone pain, hair loss, dry skin for Vitamin A; hypercalcemia for Vitamin D)
Special Patient Groups
Pregnancy
Essential vitamins and minerals are crucial during pregnancy for maternal and fetal health. However, it is critical to use a specific prenatal vitamin formulation, as excessive intake of certain vitamins (e.g., Vitamin A in its retinol form) can be teratogenic. Consult a healthcare provider for appropriate prenatal supplementation.
Trimester-Specific Risks:
First Trimester:
High doses of Vitamin A (retinol) are teratogenic and should be avoided. Folic acid is critical to prevent neural tube defects.
Second Trimester:
Continued need for essential nutrients; generally safe at recommended doses.
Third Trimester:
Continued need for essential nutrients; generally safe at recommended doses.
Lactation
Generally safe and beneficial at recommended doses. Many vitamins are excreted in breast milk, providing essential nutrients to the infant. Consult a healthcare provider for appropriate supplementation during lactation.
Infant Risk:
Low risk at recommended doses. High doses of certain vitamins (e.g., Vitamin A) could potentially be harmful to the infant, but this is rare with standard multi-vitamin use.
Pediatric Use
Age-appropriate multi-vitamin formulations are available for infants, children, and adolescents. Dosing varies significantly by age and specific product. Always use products specifically designed for children and follow recommended dosages to avoid toxicity.
Geriatric Use
Older adults may have increased needs for certain vitamins (e.g., Vitamin D, Vitamin B12 due to decreased absorption) and minerals. Multi-vitamins can be beneficial, but specific formulations tailored for seniors may be more appropriate. Consult a healthcare provider.
Clinical Information
Clinical Pearls
- Multi-vitamins are intended to supplement, not replace, a healthy diet. Emphasize dietary sources of nutrients first.
- Advise patients to take multi-vitamins with food to improve absorption of fat-soluble vitamins and reduce gastrointestinal upset.
- Educate patients on the importance of not exceeding the recommended dose, especially for fat-soluble vitamins (A, D, E, K) which can accumulate and cause toxicity.
- Be aware of potential drug-nutrient interactions, particularly with anticoagulants (Vitamin K), antibiotics (minerals), and thyroid hormones (calcium/iron).
- For specific deficiencies, targeted single-vitamin supplementation may be more appropriate than a multi-vitamin.
- Patients on specific diets (e.g., vegan, restrictive diets) or with malabsorption syndromes may have higher needs for multi-vitamin supplementation.
Alternative Therapies
- Dietary modifications to increase nutrient intake
- Individual vitamin or mineral supplements (e.g., Vitamin D, B12, Iron, Calcium)
- Herbal supplements (caution advised, not regulated like vitamins)
Cost & Coverage
Average Cost:
$5 - $30 per 30 tablets
Generic Available:
Yes
Insurance Coverage:
Generally Over-The-Counter (OTC) and not covered by most health insurance plans. Some FSA/HSA accounts may cover them.
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.