One Daily Multi-Vitamin Tablets

Manufacturer GERI-CARE Active Ingredient Vitamins (Multiple/Oral)(VYE ta mins, MUL ti pul/OR al) Pronunciation VYE ta mins, MUL ti pul/OR al
WARNING: If your product has iron in it:Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep away from children. If this drug is taken by accident, call a doctor or poison control center right away. @ COMMON USES: It is used to help growth and good health.It may be given to you for other reasons. Talk with the doctor.
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Drug Class
Nutritional Supplement
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Pharmacologic Class
Vitamins; Micronutrients
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Pregnancy Category
Not applicable (Dietary Supplement); generally considered safe and often recommended at appropriate doses (e.g., prenatal vitamins), but specific formulations and dosages should be discussed with a healthcare provider.
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FDA Approved
Jan 1970
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DEA Schedule
Not Controlled

Overview

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What is this medicine?

One Daily Multi-Vitamin Tablets are dietary supplements that contain a combination of essential vitamins and minerals. They are designed to help fill nutritional gaps in your diet and support overall health and well-being, especially when your daily food intake might not provide all the necessary nutrients.
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How to Use This Medicine

Taking Your Medication Correctly

To get the most benefit from your medication, take it exactly as directed by your doctor. Carefully read all the information provided with your prescription and follow the instructions closely.

Administration Guidelines

You can take this medication with or without food. If it causes stomach upset, taking it with food may help.
For optimal absorption, it's best to take this medication at bedtime. If you have questions about the timing, consult your doctor or pharmacist.
Extended-Release Products: Swallow the tablets whole; do not chew, break, or crush them.
Liquid Formulation: Measure the liquid dose accurately using the provided measuring device. If one is not included, ask your pharmacist for a suitable measuring device.
* Chewable Tablets: Chew the tablets thoroughly before swallowing.

Storage and Disposal

Store your medication at room temperature in a dry location, away from the bathroom. Protect it from heat and light. Keep all medications in a secure place, out of the reach of children and pets.

Missed Dose Instructions

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or take extra doses to make up for the missed one.
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Lifestyle & Tips

  • Take with food to improve absorption and reduce stomach upset.
  • Do not exceed the recommended dose unless advised by a healthcare professional.
  • Multi-vitamins are supplements and should not replace a balanced and varied diet.
  • Store in a cool, dry place, away from direct light and moisture, and out of reach of children.

Dosing & Administration

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Adult Dosing

Standard Dose: One tablet orally once daily, or as directed by a healthcare professional.
Dose Range: 1 - 1 mg

Condition-Specific Dosing:

general_health_maintenance: One tablet orally once daily.
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Pediatric Dosing

Neonatal: Not established; specific infant formulations are available.
Infant: Not established; specific infant formulations are available, consult pediatrician.
Child: Product-specific; consult product label or pediatrician for age-appropriate dosing.
Adolescent: Product-specific; consult product label or pediatrician for age-appropriate dosing, often similar to adult dose for some formulations.
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Dose Adjustments

Renal Impairment:

Mild: Generally no adjustment needed at recommended doses.
Moderate: Generally no adjustment needed at recommended doses; caution with high doses of fat-soluble vitamins (A, D) due to potential accumulation.
Severe: Caution advised; consult healthcare provider. High doses of certain vitamins (e.g., Vitamin A, D) may accumulate. Specific vitamin deficiencies or excesses may require targeted supplementation.
Dialysis: Consult healthcare provider. Specific vitamin needs may be altered (e.g., water-soluble vitamins may be dialyzed out, fat-soluble may accumulate).

Hepatic Impairment:

Mild: Generally no adjustment needed at recommended doses.
Moderate: Generally no adjustment needed at recommended doses; caution with high doses of fat-soluble vitamins (A, D, E, K) due to altered metabolism or storage.
Severe: Caution advised; consult healthcare provider. Impaired bile flow can affect absorption of fat-soluble vitamins. High doses of certain vitamins may accumulate.

Pharmacology

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Mechanism of Action

Multi-vitamins provide essential micronutrients (vitamins and minerals) that the body requires for various metabolic processes, enzyme function, cellular growth, tissue repair, immune function, and overall physiological health. They act as coenzymes, antioxidants, and structural components, supporting numerous biochemical reactions that are vital for life.
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Pharmacokinetics

Absorption:

Bioavailability: Highly variable, depends on individual vitamin/mineral, formulation, presence of food, and individual physiological factors. Water-soluble vitamins (B, C) are generally well-absorbed but not stored extensively. Fat-soluble vitamins (A, D, E, K) require dietary fat and bile for absorption and are stored in the body.
Tmax: Not acutely measurable for a multi-vitamin; absorption is continuous over time.
FoodEffect: Generally recommended to take with food to enhance absorption of fat-soluble vitamins and minimize gastrointestinal upset.

Distribution:

Vd: Not applicable for a multi-vitamin; individual components distribute widely throughout body tissues and fluids.
ProteinBinding: Variable; some vitamins/minerals bind to transport proteins (e.g., Vitamin D, B12), others circulate freely.
CnssPenetration: Variable; some vitamins (e.g., B vitamins) are essential for CNS function and cross the blood-brain barrier, others have limited penetration.

Elimination:

HalfLife: Highly variable; water-soluble vitamins typically have short half-lives (hours to days) and are readily excreted. Fat-soluble vitamins have longer half-lives (days to months) due to storage in adipose tissue and liver.
Clearance: Not applicable for a multi-vitamin; varies by individual component.
ExcretionRoute: Water-soluble vitamins primarily renal (urine). Fat-soluble vitamins primarily biliary/fecal, with some renal excretion of metabolites.
Unchanged: Variable; some water-soluble vitamins are excreted largely unchanged, while others are metabolized.
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Pharmacodynamics

OnsetOfAction: Gradual; reflects repletion of body stores and restoration of normal metabolic functions. Not an acute pharmacological effect.
PeakEffect: Not acutely measurable; sustained effect with regular intake.
DurationOfAction: Sustained with daily intake; depends on storage capacity of individual vitamins.

Safety & Warnings

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Side Effects

Urgent Side Effects: Seek Medical Help Right Away

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor immediately or seek emergency medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only mild ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms, contact your doctor for advice:

Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Green-colored stools
+ Stomach pain

Reporting Side Effects

This list is not exhaustive, and you may experience other side effects. If you have questions or concerns, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
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Seek Immediate Medical Attention If You Experience:

  • Severe stomach upset, nausea, vomiting, or diarrhea.
  • Signs of an allergic reaction: rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
  • Unusual fatigue, headache, blurred vision, or bone pain (rare, may indicate excessive intake of certain vitamins, especially fat-soluble ones).
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Before Using This Medicine

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following conditions before starting this medication:

Any allergies you have, including allergies to this drug, its components, or other substances, and describe the symptoms you experienced.
Certain types of anemia, such as pernicious anemia, where the body lacks sufficient vitamin B12.
If you are taking levodopa.
If you are taking mineral oil.
* If your product contains iron:
+ If you have an excessive amount of iron in your body.
+ If you have hemolytic anemia.

This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health issues with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other drugs and health conditions. Never start, stop, or adjust the dosage of any medication without consulting your doctor first.
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Precautions & Cautions

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This is crucial because this drug may interfere with certain laboratory tests. Therefore, be sure to notify all your healthcare providers and laboratory personnel that you are taking this medication.

If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Similarly, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.

When considering administration of this medication to a child, it is important to note that different brands may be approved for use in different age groups. Before giving this drug to a child, consult with your doctor to ensure you are using the appropriate brand and dosage for the child's age.

If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision.
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Overdose Information

Overdose Symptoms:

  • Symptoms vary depending on the specific vitamin(s) consumed in excess. Common signs can include severe gastrointestinal upset (nausea, vomiting, diarrhea), headache, dizziness, fatigue, skin changes, and in severe cases, more serious effects like liver damage (Vitamin A), kidney stones (Vitamin C, D), or nerve damage (Vitamin B6).
  • Iron overdose is particularly dangerous, especially in children, and can cause severe gastrointestinal bleeding, shock, and organ damage.

What to Do:

If an overdose is suspected, immediately contact a poison control center (1-800-222-1222 in the US) or seek emergency medical attention. Bring the product packaging with you.

Drug Interactions

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Major Interactions

  • Warfarin (Coumadin) + Vitamin K: Vitamin K can reduce the anticoagulant effect of warfarin, increasing the risk of blood clots. Patients on warfarin should maintain consistent Vitamin K intake and consult their physician before starting or stopping multi-vitamins.
  • Levodopa (L-Dopa) + Pyridoxine (Vitamin B6): High doses of Vitamin B6 (above 5-10 mg) can reduce the efficacy of levodopa by increasing its peripheral metabolism, unless a peripheral decarboxylase inhibitor (e.g., carbidopa) is co-administered.
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Moderate Interactions

  • Tetracycline antibiotics (e.g., doxycycline, minocycline) + Calcium/Iron/Magnesium/Zinc: These minerals can chelate tetracyclines, reducing their absorption and efficacy. Separate administration by at least 2-4 hours.
  • Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin) + Calcium/Iron/Magnesium/Zinc: Similar to tetracyclines, these minerals can chelate fluoroquinolones, reducing their absorption. Separate administration by at least 2-4 hours.
  • Thyroid hormones (e.g., levothyroxine) + Calcium/Iron: Calcium and iron can impair the absorption of thyroid hormones. Separate administration by at least 4 hours.
  • Bisphosphonates (e.g., alendronate) + Calcium/Iron/Magnesium: These minerals can interfere with bisphosphonate absorption. Separate administration by at least 30 minutes to 2 hours.
  • Diuretics (e.g., thiazides, loop diuretics) + various vitamins/minerals: Some diuretics can affect the excretion or retention of certain electrolytes (e.g., potassium, magnesium, calcium) or vitamins (e.g., thiamine).
  • Retinoids (e.g., isotretinoin, acitretin) + Vitamin A: Concomitant use can increase the risk of Vitamin A toxicity (hypervitaminosis A).
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Minor Interactions

  • Orlistat + Fat-soluble vitamins (A, D, E, K): Orlistat reduces fat absorption, which can impair the absorption of fat-soluble vitamins. Administer multi-vitamins at least 2 hours before or after orlistat, or at bedtime.
  • Proton Pump Inhibitors (PPIs) / H2 Blockers + Vitamin B12: Long-term use of acid-reducing medications can impair the absorption of Vitamin B12 due to reduced gastric acid production.

Monitoring

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Baseline Monitoring

Dietary intake assessment

Rationale: To determine if a multi-vitamin is necessary to supplement an inadequate diet.

Timing: Prior to initiation, especially if concerns about nutritional status exist.

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Routine Monitoring

General well-being and absence of deficiency symptoms

Frequency: Ongoing

Target: Not applicable

Action Threshold: Development of new symptoms or worsening of existing conditions that may indicate deficiency or excess.

Absence of adverse effects (e.g., GI upset, allergic reaction)

Frequency: Ongoing

Target: Not applicable

Action Threshold: Occurrence of any adverse effects.

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Symptom Monitoring

  • Gastrointestinal upset (nausea, constipation, diarrhea)
  • Allergic reactions (rash, itching, swelling, dizziness, trouble breathing)
  • Symptoms of hypervitaminosis (rare at recommended doses, but can include headache, fatigue, blurred vision, bone pain, hair loss, liver dysfunction, nerve damage depending on specific vitamin excess)
  • Symptoms of specific vitamin deficiencies if not adequately addressed by the multi-vitamin (e.g., fatigue, weakness, skin changes, neurological symptoms)

Special Patient Groups

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Pregnancy

Generally safe and often recommended, especially prenatal multi-vitamins specifically formulated for pregnancy. These typically contain higher levels of folic acid and iron. However, excessive intake of certain vitamins (e.g., Vitamin A in its retinol form) can be teratogenic. Always consult a healthcare provider before taking any supplements during pregnancy.

Trimester-Specific Risks:

First Trimester: Crucial for neural tube development, requiring adequate folic acid. Avoid excessive Vitamin A (retinol).
Second Trimester: Continued need for various nutrients for fetal growth and maternal health.
Third Trimester: Increased iron needs to support fetal blood volume and prevent maternal anemia.
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Lactation

Generally safe and often recommended to support maternal nutritional needs and ensure adequate nutrient transfer to breast milk. Specific postnatal multi-vitamins are available. Consult a healthcare provider.

Infant Risk: Low risk at recommended doses. Excessive maternal intake of certain vitamins could potentially lead to high levels in breast milk, but this is rare with standard multi-vitamins.
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Pediatric Use

Age-appropriate formulations and dosages are crucial. Children have different nutritional needs than adults, and some adult multi-vitamins may contain excessive amounts of certain vitamins/minerals for children, potentially leading to toxicity (e.g., iron poisoning). Always use products specifically designed for children and follow dosing instructions carefully.

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Geriatric Use

Generally safe and may be beneficial as older adults may have altered absorption, increased needs (e.g., Vitamin B12, Vitamin D), or reduced dietary intake. However, caution with high doses of certain vitamins (e.g., Vitamin A) due to potential for accumulation or interactions with medications. Consult a healthcare provider for personalized recommendations.

Clinical Information

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Clinical Pearls

  • Multi-vitamins are intended to supplement, not replace, a healthy and balanced diet.
  • The 'best' multi-vitamin varies by individual needs, age, sex, and specific dietary gaps. Consider consulting a healthcare professional or registered dietitian.
  • Pay attention to the 'USP Verified' mark or other third-party certifications (e.g., NSF, ConsumerLab) to ensure product quality, purity, and accurate labeling, as dietary supplements are not as strictly regulated as prescription drugs.
  • Be aware of potential interactions with prescription medications, especially anticoagulants (warfarin), certain antibiotics, and thyroid hormones.
  • Iron-containing multi-vitamins should be kept out of reach of children due to the risk of accidental iron poisoning.
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Alternative Therapies

  • Dietary modifications to increase intake of nutrient-rich foods.
  • Targeted single vitamin or mineral supplements for specific deficiencies (e.g., Vitamin D, B12, Iron).
  • Fortified foods (e.g., cereals, milk).
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Cost & Coverage

Average Cost: Variable, typically $5 - $30+ per 30 tablets
Generic Available: Yes
Insurance Coverage: Often not covered by insurance; considered over-the-counter (OTC) dietary supplements. Some FSA/HSA eligibility.
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General Drug Facts

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about this medication, don't hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When reporting the incident, be prepared to provide details about the medication taken, the amount, and the time it occurred.