Mvw D5000 Softgel Capsules

Manufacturer MVW NUTRITIONALS Active Ingredient Vitamins (Multiple/Oral)(VYE ta mins, MUL ti pul/OR al) Pronunciation VYE-tuh-mins, MUL-tih-pul/OR-uhl
WARNING: If your product has iron in it:Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep away from children. If this drug is taken by accident, call a doctor or poison control center right away. @ COMMON USES: It is used to help growth and good health.It may be given to you for other reasons. Talk with the doctor.
đŸˇī¸
Drug Class
Nutritional Supplement; Vitamin Supplement
đŸ§Ŧ
Pharmacologic Class
Vitamins; Fat-soluble vitamins (e.g., Vitamin D); Water-soluble vitamins
🤰
Pregnancy Category
Not applicable (Dietary Supplement); consult healthcare provider for specific vitamin needs during pregnancy.
✅
FDA Approved
Jan 1970
âš–ī¸
DEA Schedule
Not Controlled

Overview

â„šī¸

What is this medicine?

Mvw D5000 Softgel Capsules are a dietary supplement containing multiple vitamins, with a significant amount of Vitamin D (5000 IU). Vitamins are essential nutrients your body needs in small amounts to function properly, grow, and stay healthy. They help with various body processes, from energy production to bone health and immune function. This supplement helps ensure you get enough of these vital nutrients, especially Vitamin D, which is important for strong bones and overall well-being.
📋

How to Use This Medicine

Taking Your Medication Correctly

To get the most benefit from your medication, follow your doctor's instructions and read all the information provided. Take your medication as directed, and follow these guidelines:

You can take this medication with or without food. If it causes stomach upset, take it with food to help minimize discomfort.
For best absorption, take this medication at bedtime. If you have questions about the timing of your dose, consult your doctor or pharmacist.
Extended-Release Products: Swallow the tablet whole; do not chew, break, or crush it.
Liquid Medication: Measure your dose carefully using the provided measuring device. If one is not included, ask your pharmacist for a suitable device to ensure accurate measurement.
Chewable Tablets: Chew the tablet thoroughly before swallowing to ensure proper absorption.

Storing and Disposing of Your Medication

To maintain the effectiveness and safety of your medication:

Store it at room temperature in a dry place, avoiding the bathroom.
Protect it from heat and light to prevent degradation.
Keep all medications in a secure location, out of the reach of children and pets.

What to Do If You Miss a Dose

If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time or take extra doses to make up for the missed one.
💡

Lifestyle & Tips

  • Take with food, especially a meal containing some fat, to improve the absorption of fat-soluble vitamins (like Vitamin D).
  • Do not exceed the recommended dose unless specifically advised by your healthcare provider.
  • Maintain a balanced diet rich in fruits, vegetables, and whole grains, as supplements are intended to complement, not replace, a healthy diet.
  • Store in a cool, dry place away from direct light and out of reach of children.

Dosing & Administration

đŸ‘¨â€âš•ī¸

Adult Dosing

Standard Dose: Typically one softgel daily, or as directed by a healthcare professional. Contains 5000 IU Vitamin D3, which exceeds the recommended daily allowance for most adults and is often used for deficiency correction or maintenance.
Dose Range: 1 - 1 mg

Condition-Specific Dosing:

Vitamin D Deficiency: Dosing may vary based on severity of deficiency and healthcare provider's recommendation, often higher initial doses followed by maintenance.
đŸ‘ļ

Pediatric Dosing

Neonatal: Not established; consult pediatrician for age-appropriate vitamin supplementation.
Infant: Not established; consult pediatrician for age-appropriate vitamin supplementation.
Child: Not established; consult pediatrician for age-appropriate vitamin supplementation. High doses of fat-soluble vitamins can be toxic.
Adolescent: Not established; consult pediatrician for age-appropriate vitamin supplementation. High doses of fat-soluble vitamins can be toxic.
âš•ī¸

Dose Adjustments

Renal Impairment:

Mild: No specific adjustment for standard supplement doses. Monitor for hypercalcemia if high dose Vitamin D is used.
Moderate: Caution with high doses of fat-soluble vitamins (especially Vitamin A and D) due to potential accumulation. Monitor calcium and phosphate levels. Consult healthcare provider.
Severe: Caution with high doses of fat-soluble vitamins (especially Vitamin A and D) due to potential accumulation and toxicity. Monitor calcium and phosphate levels closely. Consult healthcare provider.
Dialysis: Consult healthcare provider. Specific vitamin needs may vary for dialysis patients; high doses of Vitamin D may require careful monitoring.

Hepatic Impairment:

Mild: No specific adjustment for standard supplement doses.
Moderate: Caution with high doses of fat-soluble vitamins (especially Vitamin A and D) in severe hepatic impairment. Consult healthcare provider.
Severe: Caution with high doses of fat-soluble vitamins (especially Vitamin A and D) in severe hepatic impairment. Consult healthcare provider.

Pharmacology

đŸ”Ŧ

Mechanism of Action

Vitamins are essential organic compounds required in small quantities for normal metabolic function, growth, and overall health. They act as coenzymes, antioxidants, and regulators of various physiological processes. Vitamin D, specifically, plays a crucial role in calcium and phosphate homeostasis, bone mineralization, and immune function by binding to the vitamin D receptor (VDR) and regulating gene expression.
📊

Pharmacokinetics

Absorption:

Bioavailability: Variable (e.g., Vitamin D bioavailability is high, but depends on fat intake and individual factors)
Tmax: Highly variable, not typically reported for supplements (e.g., for Vitamin D, peak serum 25(OH)D levels may take days to weeks after a single dose)
FoodEffect: Fat-soluble vitamins (A, D, E, K) are best absorbed when taken with a fatty meal. Water-soluble vitamins (B, C) are generally absorbed well regardless of food, though some may have improved absorption with food.

Distribution:

Vd: Variable (e.g., fat-soluble vitamins distribute extensively into adipose tissue; water-soluble vitamins distribute into total body water)
ProteinBinding: Variable (e.g., Vitamin D and its metabolites bind extensively to vitamin D-binding protein (DBP) and albumin)
CnssPenetration: Limited for most vitamins; some B vitamins (e.g., B1, B6, B12) cross the blood-brain barrier to varying degrees.

Elimination:

HalfLife: Variable (e.g., 25-hydroxyvitamin D has a half-life of approximately 2-3 weeks; water-soluble vitamins have shorter half-lives, typically hours)
Clearance: Variable
ExcretionRoute: Water-soluble vitamins are primarily excreted renally. Fat-soluble vitamins and their metabolites are primarily excreted via bile into feces, with some renal excretion of metabolites.
Unchanged: Variable (e.g., excess water-soluble vitamins are largely excreted unchanged in urine)
âąī¸

Pharmacodynamics

OnsetOfAction: Gradual (weeks to months for correction of deficiency)
PeakEffect: Not applicable in the same way as acute-acting drugs; effects are cumulative over time.
DurationOfAction: Sustained as long as adequate intake/stores are maintained.

Safety & Warnings

âš ī¸

Side Effects

Urgent Side Effects: Seek Medical Attention Immediately

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical help right away:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:

Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Change in stool color to green
+ Stomach pain

Note: This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
🚨

Seek Immediate Medical Attention If You Experience:

  • Symptoms of too much Vitamin D (hypercalcemia): Nausea, vomiting, constipation, frequent urination, excessive thirst, muscle weakness, fatigue, confusion, bone pain, or kidney stones. Seek immediate medical attention if these occur.
  • Symptoms of other vitamin toxicities (less common with typical doses but possible with excessive intake): Dry skin, hair loss, headache, blurred vision, liver problems (for Vitamin A); nerve damage (for very high Vitamin B6).
📋

Before Using This Medicine

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following conditions before starting this medication:

Any allergies you have, including allergies to this drug, its components, or other substances, and describe the symptoms you experienced.
Certain types of anemia, such as pernicious anemia, where the body lacks sufficient vitamin B12.
If you are taking levodopa.
If you are taking mineral oil.
* If your product contains iron:
+ If you have an excessive amount of iron in your body (iron overload).
+ If you have hemolytic anemia, a condition where red blood cells are destroyed faster than they can be made.

This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions. Never start, stop, or change the dose of any medication without consulting your doctor first.
âš ī¸

Precautions & Cautions

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This is crucial because this drug may interfere with certain laboratory tests. Therefore, be sure to notify all your healthcare providers and laboratory personnel that you are taking this medication.

If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Similarly, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.

When considering administering this medication to a child, it is vital to consult with your doctor first, as different brands of this drug may be approved for use in children of varying ages.

If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of taking this medication to ensure the best possible outcome for both you and your baby.
🆘

Overdose Information

Overdose Symptoms:

  • Severe nausea, vomiting, diarrhea, abdominal pain
  • Extreme fatigue, weakness, confusion, irritability
  • Excessive thirst and urination
  • Bone pain, joint pain
  • Kidney stones, kidney damage
  • Cardiac arrhythmias (in severe hypercalcemia)

What to Do:

If you suspect an overdose, contact a poison control center immediately. In the U.S., call 1-800-222-1222. Seek emergency medical attention if symptoms are severe.

Drug Interactions

đŸšĢ

Contraindicated Interactions

  • Known hypersensitivity to any component of the formulation
  • Hypercalcemia (for Vitamin D containing products)
  • Hypervitaminosis A or D (if product contains high doses of these vitamins)
🔴

Major Interactions

  • Warfarin (Coumadin) - Vitamin K can antagonize the anticoagulant effect of warfarin.
  • Orlistat (Xenical, Alli) - Can reduce absorption of fat-soluble vitamins (A, D, E, K).
  • Cholestyramine (Questran), Colestipol (Colestid), Mineral Oil - Can reduce absorption of fat-soluble vitamins.
  • Thiazide diuretics (e.g., Hydrochlorothiazide) - Can increase risk of hypercalcemia when taken with high doses of Vitamin D.
🟡

Moderate Interactions

  • Anticonvulsants (e.g., Phenytoin, Carbamazepine, Phenobarbital) - Can affect Vitamin D metabolism, potentially leading to deficiency.
  • Isoniazid - Can interfere with Vitamin B6 (pyridoxine) metabolism.
  • Methotrexate - Can interfere with folate metabolism.
  • Corticosteroids - Can impair calcium absorption and Vitamin D metabolism.
  • Digoxin - High calcium levels (due to Vitamin D toxicity) can increase the risk of digoxin toxicity.
đŸŸĸ

Minor Interactions

  • Many, generally minor for typical supplement doses. Consult a healthcare professional for specific concerns.

Monitoring

đŸ”Ŧ

Baseline Monitoring

Serum 25-hydroxyvitamin D levels

Rationale: To assess baseline vitamin D status, especially if used for deficiency correction.

Timing: Prior to initiation of high-dose Vitamin D supplementation.

Serum calcium and phosphate levels

Rationale: To establish baseline and monitor for potential hypercalcemia or hyperphosphatemia, particularly with high-dose Vitamin D.

Timing: Prior to initiation of high-dose Vitamin D supplementation.

Renal function (BUN, Creatinine)

Rationale: To assess kidney health, as severe impairment can affect vitamin metabolism and excretion, and hypercalcemia can impact renal function.

Timing: Prior to initiation of high-dose Vitamin D supplementation, especially in patients with pre-existing renal conditions.

📊

Routine Monitoring

Serum 25-hydroxyvitamin D levels

Frequency: Every 3-6 months until target levels are achieved, then annually for maintenance, or as clinically indicated.

Target: Typically 30-100 ng/mL (75-250 nmol/L) for optimal health, depending on guidelines.

Action Threshold: Levels below target may indicate need for dose adjustment; levels significantly above target may indicate excessive supplementation.

Serum calcium and phosphate levels

Frequency: Periodically (e.g., every 3-6 months) with high-dose Vitamin D supplementation, or if symptoms of hypercalcemia develop.

Target: Calcium: 8.5-10.2 mg/dL; Phosphate: 2.5-4.5 mg/dL (adults)

Action Threshold: Elevated levels (hypercalcemia, hyperphosphatemia) require immediate medical evaluation and dose adjustment.

đŸ‘ī¸

Symptom Monitoring

  • Symptoms of vitamin deficiency (e.g., fatigue, bone pain, muscle weakness, impaired vision, skin changes, neurological symptoms)
  • Symptoms of hypervitaminosis (toxicity), especially for fat-soluble vitamins (A, D, E, K):
  • For Vitamin D toxicity (hypercalcemia): Nausea, vomiting, constipation, polyuria, polydipsia, muscle weakness, fatigue, confusion, bone pain, kidney stones, cardiac arrhythmias.
  • For Vitamin A toxicity: Dry skin, hair loss, fatigue, headache, blurred vision, liver damage, bone pain.
  • For other vitamin toxicities: Consult specific vitamin information.

Special Patient Groups

🤰

Pregnancy

Vitamins are essential during pregnancy for both maternal health and fetal development. However, specific prenatal vitamins are formulated to meet the unique needs of pregnancy and avoid excessive doses of certain vitamins (e.g., Vitamin A in its retinol form, which can be teratogenic at high doses). High doses of Vitamin D (5000 IU) should be used cautiously and only under medical supervision during pregnancy.

Trimester-Specific Risks:

First Trimester: High doses of Vitamin A (retinol) are teratogenic. Consult healthcare provider for appropriate prenatal vitamin supplementation.
Second Trimester: Generally safe if within recommended daily allowances. High doses of Vitamin D should be monitored.
Third Trimester: Generally safe if within recommended daily allowances. High doses of Vitamin D should be monitored.
🤱

Lactation

Vitamins are excreted in breast milk and are important for infant nutrition. Supplementation may be necessary for the mother, but high doses of any vitamin should be avoided without medical advice to prevent potential adverse effects on the infant.

Infant Risk: Low risk with appropriate doses; high doses of fat-soluble vitamins could potentially accumulate in breast milk and pose a risk to the infant.
đŸ‘ļ

Pediatric Use

Age-appropriate formulations and dosages are crucial for children. High doses of fat-soluble vitamins (A, D, E, K) can be toxic in children due to their lower body weight and different metabolic rates. Consult a pediatrician before administering any vitamin supplement to children.

👴

Geriatric Use

Older adults may have increased risk of certain vitamin deficiencies (e.g., Vitamin D, B12) due to decreased absorption, reduced sun exposure, or dietary changes. Supplementation may be beneficial, but caution with excessive doses is advised, especially for fat-soluble vitamins, due to potential for accumulation and interactions with other medications.

Clinical Information

💎

Clinical Pearls

  • Mvw D5000 Softgel Capsules likely contain 5000 IU of Vitamin D3, which is a higher dose than the typical Recommended Daily Allowance (RDA) for most adults. This dose is often used for correcting Vitamin D deficiency or for maintenance in individuals with specific needs.
  • Always advise patients to inform their healthcare provider about all supplements they are taking, especially if they are on other medications, to avoid potential interactions.
  • Emphasize that dietary supplements are not a substitute for a balanced diet. Encourage patients to obtain vitamins primarily from food sources.
  • Educate patients on the symptoms of hypervitaminosis, particularly for Vitamin D, as toxicity can occur with excessive intake.
  • For patients with malabsorption syndromes (e.g., cystic fibrosis, Crohn's disease, celiac disease, bariatric surgery), higher doses of fat-soluble vitamins may be necessary, but should be guided by a healthcare professional and monitored.
🔄

Alternative Therapies

  • Dietary intake of vitamin-rich foods (e.g., fatty fish, fortified dairy for Vitamin D; fruits and vegetables for other vitamins)
  • Sunlight exposure for Vitamin D synthesis
💰

Cost & Coverage

Average Cost: Price varies widely by retailer and specific formulation (e.g., $10-$30) per 30-100 softgels
Generic Available: Yes
Insurance Coverage: Not typically covered by insurance (Over-the-Counter dietary supplement)
📚

General Drug Facts

If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication, including the amount taken and the time it happened, to help healthcare professionals provide the best possible care.