Mvw D3000 Softgels

Manufacturer MVW NUTRITIONALS Active Ingredient Vitamins (Multiple/Oral)(VYE ta mins, MUL ti pul/OR al) Pronunciation Em-vee-double-you Dee three-thousand Soft-jels
WARNING: If your product has iron in it:Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep away from children. If this drug is taken by accident, call a doctor or poison control center right away. @ COMMON USES: It is used to help growth and good health.It may be given to you for other reasons. Talk with the doctor.
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Drug Class
Nutritional Supplement; Vitamin Supplement
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Pharmacologic Class
Vitamins; Micronutrients
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Pregnancy Category
Not assigned (Dietary Supplement); individual vitamins vary (e.g., A, C, D)
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FDA Approved
Jan 1970
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DEA Schedule
Not Controlled

Overview

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What is this medicine?

Mvw D3000 Softgels is a daily dietary supplement that provides a blend of essential vitamins, including a significant amount of Vitamin D (3000 IU). It helps ensure your body gets the necessary nutrients it might be missing from your diet, supporting overall health, bone strength, and immune function.
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How to Use This Medicine

Taking Your Medication Correctly

To get the most benefit from your medication, follow your doctor's instructions carefully. Read all the information provided with your prescription and follow the instructions closely.

You can take this medication with or without food. If it causes stomach upset, taking it with food may help.
For best absorption, take this medication at bedtime. If you have questions about the timing of your dose, consult your doctor or pharmacist.
Extended-Release Products: Swallow the tablets whole; do not chew, break, or crush them.
Liquid Medication: Measure your dose carefully using the measuring device provided with the medication. If one is not included, ask your pharmacist for a device to measure your dose accurately.
Chewable Tablets: Chew the tablets thoroughly before swallowing.

Storing and Disposing of Your Medication

Store your medication at room temperature in a dry place, away from the bathroom.
Protect your medication from heat and light.
Keep all medications in a safe location, out of the reach of children and pets.

What to Do if You Miss a Dose

If you miss a dose, take it as soon as you remember.
If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
* Do not take two doses at the same time or take extra doses.
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Lifestyle & Tips

  • Take with food, especially a meal containing some fat, to enhance the absorption of fat-soluble vitamins (A, D, E, K).
  • Do not exceed the recommended dose unless specifically advised by your healthcare provider.
  • Maintain a balanced diet rich in fruits, vegetables, and whole grains.
  • Regular exercise and adequate sleep contribute to overall health.
  • Inform your healthcare provider about all supplements and medications you are taking.

Dosing & Administration

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Adult Dosing

Standard Dose: One softgel daily, or as directed by a healthcare professional.
Dose Range: 1 - 2 mg

Condition-Specific Dosing:

general_supplementation: One softgel daily.
specific_deficiency: Higher doses may be recommended by a healthcare professional based on specific vitamin deficiencies.
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Pediatric Dosing

Neonatal: Not established; consult pediatrician.
Infant: Not established; consult pediatrician.
Child: Not established; consult pediatrician. Dosing varies significantly by age and specific vitamin content.
Adolescent: Not established; consult pediatrician. Dosing varies significantly by age and specific vitamin content.
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Dose Adjustments

Renal Impairment:

Mild: Generally no specific adjustment required for standard doses. Monitor for specific vitamin levels (e.g., Vitamin A, D) if high doses are used.
Moderate: Generally no specific adjustment required for standard doses. Monitor for specific vitamin levels (e.g., Vitamin A, D) if high doses are used. Avoid excessive Vitamin A and D.
Severe: Use with caution. Avoid excessive Vitamin A and D due to potential for accumulation and toxicity. Consult nephrologist.
Dialysis: Use with caution. Specific vitamin supplementation may be required, but avoid excessive fat-soluble vitamins (A, D, E, K). Consult nephrologist.

Hepatic Impairment:

Mild: Generally no specific adjustment required for standard doses.
Moderate: Generally no specific adjustment required for standard doses. Monitor for specific vitamin levels if high doses are used.
Severe: Use with caution. Impaired bile flow can affect absorption of fat-soluble vitamins. Consult hepatologist.

Pharmacology

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Mechanism of Action

Vitamins are essential organic compounds that the body needs in small amounts for various metabolic processes. They act as coenzymes, antioxidants, hormones, or structural components, playing crucial roles in energy production, immune function, bone health, vision, and cellular repair. Mvw D3000 Softgels, containing multiple vitamins and notably 3000 IU of Vitamin D3, aims to supplement dietary intake to prevent or correct deficiencies.
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Pharmacokinetics

Absorption:

Bioavailability: Highly variable depending on specific vitamin (water-soluble vs. fat-soluble), formulation, and presence of food. Fat-soluble vitamins (A, D, E, K) require dietary fat for optimal absorption. Water-soluble vitamins (B vitamins, C) are generally well-absorbed.
Tmax: Not applicable for a multi-vitamin product; varies widely by individual vitamin (e.g., Vitamin D peak plasma concentration typically 4-8 hours post-ingestion).
FoodEffect: Absorption of fat-soluble vitamins is enhanced with food, especially fatty meals. Water-soluble vitamins can be taken with or without food, though some B vitamins may be better absorbed with food.

Distribution:

Vd: Highly variable; water-soluble vitamins distribute into body water, while fat-soluble vitamins are stored in adipose tissue and liver.
ProteinBinding: Varies by vitamin (e.g., Vitamin D metabolites are highly protein-bound).
CnssPenetration: Limited for most vitamins; some B vitamins (e.g., thiamine) are actively transported.

Elimination:

HalfLife: Highly variable (e.g., Vitamin C: 2-3 hours; Vitamin D: 2-3 weeks for parent compound, longer for metabolites).
Clearance: Varies by vitamin and individual metabolic rate.
ExcretionRoute: Water-soluble vitamins primarily renal; fat-soluble vitamins primarily biliary/fecal after hepatic metabolism.
Unchanged: Varies; significant portion of water-soluble vitamins may be excreted unchanged.
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Pharmacodynamics

OnsetOfAction: Not applicable in the acute sense for a multi-vitamin; benefits accrue over time with consistent supplementation.
PeakEffect: Not applicable.
DurationOfAction: Not applicable; sustained benefits with regular intake.

Safety & Warnings

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Side Effects

Urgent Side Effects: Seek Medical Attention Immediately

Although rare, some individuals may experience severe and potentially life-threatening side effects while taking this medication. If you exhibit any of the following symptoms, contact your doctor or seek medical help right away:

Signs of an allergic reaction, including:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:

Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Change in stool color to green
+ Stomach pain

Important Note

This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
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Seek Immediate Medical Attention If You Experience:

  • Severe nausea or vomiting
  • Persistent constipation or diarrhea
  • Unusual fatigue or weakness
  • Increased thirst or urination
  • Bone or muscle pain
  • Headache or dizziness
  • Skin rash or itching
  • Any signs of allergic reaction (e.g., swelling of face/throat, difficulty breathing)
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Before Using This Medicine

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following conditions to ensure safe use of this medication:

Any allergies you have, including allergies to this drug, its components, or other substances, and describe the symptoms you experienced.
Certain types of anemia, such as pernicious anemia, where the body lacks sufficient vitamin B12.
If you are taking levodopa or mineral oil.
If your product contains iron and you have:
+ Excessive iron levels in your body.
+ Hemolytic anemia.

This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other drugs and health problems. Never start, stop, or adjust the dosage of any medication without consulting your doctor first.
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Precautions & Cautions

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This is crucial because this drug may interfere with certain laboratory tests. Therefore, be sure to notify all your healthcare providers and laboratory personnel that you are taking this medication.

If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Similarly, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.

When it comes to administering this medication to children, it is important to note that different brands may be suitable for different age groups. Before giving this drug to a child, consult with your doctor to ensure you are using the appropriate brand and dosage.

If you are pregnant, planning to become pregnant, or are breastfeeding, it is crucial to discuss the potential benefits and risks of this medication with your doctor. This will help you make an informed decision about taking the medication, considering the potential effects on you and your baby.
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Overdose Information

Overdose Symptoms:

  • Hypercalcemia (due to excessive Vitamin D): Nausea, vomiting, constipation, loss of appetite, increased thirst, increased urination, muscle weakness, bone pain, confusion, kidney stones, kidney damage.
  • Hypervitaminosis A: Dry skin, cracked lips, hair loss, headache, blurred vision, liver damage.
  • Hypervitaminosis B6: Nerve damage (neuropathy), numbness, tingling.
  • Hypervitaminosis C: Diarrhea, abdominal cramps, kidney stones (rare).

What to Do:

Discontinue use immediately. Seek emergency medical attention or call Poison Control at 1-800-222-1222. Treatment is supportive and may involve hydration and measures to reduce calcium levels if hypercalcemia is present.

Drug Interactions

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Contraindicated Interactions

  • Not applicable for general multi-vitamins, but specific high-dose vitamins may be contraindicated in certain conditions (e.g., Vitamin K in patients with clotting disorders not on warfarin).
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Major Interactions

  • Warfarin (Coumadin) + Vitamin K: Vitamin K can reduce the anticoagulant effect of warfarin.
  • Anticonvulsants (e.g., phenytoin, phenobarbital) + Vitamin D: May increase Vitamin D metabolism, leading to deficiency.
  • Orlistat (Xenical, Alli) + Fat-soluble vitamins (A, D, E, K): Orlistat reduces fat absorption, potentially leading to deficiency of fat-soluble vitamins.
  • Tetracyclines/Quinolones + Calcium/Iron/Magnesium (often in multi-vitamins): Reduced absorption of antibiotics due to chelation.
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Moderate Interactions

  • Thiazide diuretics + Calcium/Vitamin D: May increase risk of hypercalcemia.
  • Cholestyramine/Colestipol + Fat-soluble vitamins: May reduce absorption of fat-soluble vitamins.
  • Mineral oil + Fat-soluble vitamins: May reduce absorption of fat-soluble vitamins.
  • Antiplatelet/Anticoagulant drugs + High-dose Vitamin E: May increase risk of bleeding.
  • Proton Pump Inhibitors (PPIs) + Vitamin B12: Long-term PPI use may impair B12 absorption.
  • Metformin + Vitamin B12: May impair B12 absorption.
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Minor Interactions

  • Alcohol + B vitamins: Chronic alcohol consumption can deplete B vitamins.

Monitoring

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Baseline Monitoring

Dietary intake assessment

Rationale: To identify potential dietary gaps and determine the need for supplementation.

Timing: Prior to initiation of supplementation.

Relevant vitamin levels (e.g., 25-hydroxyvitamin D, B12, folate)

Rationale: If specific deficiencies are suspected or to establish baseline for high-dose supplementation.

Timing: Prior to initiation, especially for high-dose Vitamin D (3000 IU).

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Routine Monitoring

Symptoms of deficiency or toxicity

Frequency: Ongoing, patient self-monitoring.

Target: Absence of symptoms.

Action Threshold: Report any new or worsening symptoms to healthcare provider.

Serum 25-hydroxyvitamin D (for high-dose Vitamin D)

Frequency: Every 3-6 months initially, then annually, or as clinically indicated.

Target: 30-100 ng/mL (75-250 nmol/L).

Action Threshold: Levels below 30 ng/mL may indicate insufficient dosing; levels above 100 ng/mL may indicate excessive dosing and risk of toxicity.

Serum Calcium and Phosphorus (for high-dose Vitamin D)

Frequency: Annually or as clinically indicated, especially if high doses are used or renal impairment is present.

Target: Calcium: 8.5-10.2 mg/dL; Phosphorus: 2.5-4.5 mg/dL.

Action Threshold: Elevated calcium or phosphorus may indicate Vitamin D toxicity.

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Symptom Monitoring

  • Fatigue
  • Weakness
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Headache
  • Dizziness
  • Muscle pain
  • Bone pain
  • Increased thirst
  • Increased urination
  • Loss of appetite
  • Skin rash
  • Itching
  • Yellowing of skin/eyes (jaundice)
  • Numbness or tingling (paresthesias)
  • Changes in vision
  • Unusual bleeding or bruising

Special Patient Groups

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Pregnancy

Consult a healthcare provider before use. While essential vitamins are crucial during pregnancy, excessive intake of certain vitamins (e.g., Vitamin A in high doses) can be harmful. A prenatal vitamin specifically formulated for pregnancy is generally recommended.

Trimester-Specific Risks:

First Trimester: High doses of Vitamin A (retinol) can be teratogenic. Ensure total intake from diet and supplements does not exceed recommended upper limits.
Second Trimester: Generally safe if within recommended daily allowances. Focus on adequate intake of folate, iron, and Vitamin D.
Third Trimester: Generally safe if within recommended daily allowances. Continue to monitor for adequate intake of essential nutrients.
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Lactation

Consult a healthcare provider before use. Vitamins are excreted in breast milk. While essential for infant health, excessive intake of certain vitamins by the mother could potentially lead to high levels in breast milk. A postnatal or general multi-vitamin at recommended doses is usually safe.

Infant Risk: Low risk with standard doses; potential for adverse effects with excessive maternal intake of certain vitamins (e.g., Vitamin D, Vitamin A).
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Pediatric Use

Not typically recommended for children without specific guidance from a pediatrician. Dosing and specific vitamin needs vary significantly by age and weight. Pediatric-specific multi-vitamins are available.

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Geriatric Use

Generally safe and potentially beneficial, as older adults may have reduced absorption or increased needs for certain vitamins (e.g., Vitamin D, B12). However, monitor for potential interactions with multiple medications and pre-existing conditions. High-dose Vitamin D (3000 IU) is often appropriate for older adults to maintain bone health.

Clinical Information

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Clinical Pearls

  • Mvw D3000 Softgels is a dietary supplement, not a prescription drug. Its efficacy and safety are not evaluated by the FDA to the same extent as pharmaceuticals.
  • The 'D3000' in the name likely indicates 3000 IU of Vitamin D3, which is a higher dose than typically found in standard multi-vitamins and may be beneficial for individuals with Vitamin D deficiency or at risk of deficiency (e.g., limited sun exposure, older adults).
  • Always take multi-vitamins with food to improve absorption, especially for fat-soluble vitamins.
  • Educate patients that supplements are not a substitute for a healthy, balanced diet.
  • Advise patients to disclose all supplements they are taking to their healthcare providers to avoid potential drug-nutrient interactions or excessive intake of certain vitamins.
  • Symptoms of hypervitaminosis (vitamin toxicity) can be subtle and mimic other conditions; encourage patients to report any unusual symptoms.
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Alternative Therapies

  • Dietary modifications to increase vitamin intake from food sources.
  • Individual vitamin supplements for specific deficiencies (e.g., Vitamin D alone, B-complex, Vitamin C).
  • Sun exposure for Vitamin D synthesis (with appropriate sun protection).
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Cost & Coverage

Average Cost: Highly variable, typically $10-$30 per 30-90 softgels
Generic Available: Yes
Insurance Coverage: Not typically covered by insurance, as it is a dietary supplement. May be eligible for FSA/HSA.
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General Drug Facts

If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.