Drysol Dab-O-matic 35ml
It is used to treat very bad sweating.
Drug Class
Antiperspirant
Pharmacologic Class
Astringent; Antiperspirant
Pregnancy Category
Not available
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Drysol is a strong antiperspirant used to reduce excessive sweating (hyperhidrosis). It works by temporarily blocking your sweat glands, preventing sweat from reaching the skin surface.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. This medication is for topical use only, meaning it should be applied directly to the affected area of your skin. Avoid getting it in your mouth, nose, or eyes, as it may cause burning.
Application Instructions
1. Wash your hands before and after applying the medication, unless your hand is the area being treated.
2. Clean the affected area before application and dry it thoroughly.
3. Apply a thin layer of the medication to the affected area at bedtime.
4. To apply, turn the bottle upside down and use light pressure to dispense the solution. Avoid using excessive pressure on the bottle.
5. Do not use this medication as a roll-on.
Post-Application Care
1. If directed by your doctor, you may cover the treated area with plastic wrap, followed by a T-shirt, mitten, shower cap, or sock.
2. In the morning, wash the affected area with water and gently pat it dry.
Important Safety Precautions
This medication is flammable, so avoid using it near an open flame or while smoking.
Do not apply this medication to broken or irritated skin, or to skin that has been shaved recently.
Storage and Disposal
Store this medication at room temperature with the lid tightly closed.
Protect it from heat and open flames.
* Keep all medications in a safe place, out of the reach of children and pets.
Missed Dose
If you miss a dose, skip it and resume your normal application schedule. Do not apply extra doses or double doses. Since this medication is often used as needed, follow your doctor's instructions regarding frequency of use and do not use it more often than recommended.
To use this medication correctly, follow your doctor's instructions and read all the information provided. This medication is for topical use only, meaning it should be applied directly to the affected area of your skin. Avoid getting it in your mouth, nose, or eyes, as it may cause burning.
Application Instructions
1. Wash your hands before and after applying the medication, unless your hand is the area being treated.
2. Clean the affected area before application and dry it thoroughly.
3. Apply a thin layer of the medication to the affected area at bedtime.
4. To apply, turn the bottle upside down and use light pressure to dispense the solution. Avoid using excessive pressure on the bottle.
5. Do not use this medication as a roll-on.
Post-Application Care
1. If directed by your doctor, you may cover the treated area with plastic wrap, followed by a T-shirt, mitten, shower cap, or sock.
2. In the morning, wash the affected area with water and gently pat it dry.
Important Safety Precautions
This medication is flammable, so avoid using it near an open flame or while smoking.
Do not apply this medication to broken or irritated skin, or to skin that has been shaved recently.
Storage and Disposal
Store this medication at room temperature with the lid tightly closed.
Protect it from heat and open flames.
* Keep all medications in a safe place, out of the reach of children and pets.
Missed Dose
If you miss a dose, skip it and resume your normal application schedule. Do not apply extra doses or double doses. Since this medication is often used as needed, follow your doctor's instructions regarding frequency of use and do not use it more often than recommended.
Lifestyle & Tips
- Apply to completely dry skin at bedtime. Moisture can cause irritation.
- Do not apply to broken, irritated, or recently shaved skin.
- Wash off the product in the morning with soap and water.
- Avoid contact with eyes, mouth, and other mucous membranes.
- Avoid contact with clothing or jewelry as it may stain or damage them.
- Reduce application frequency once sweating is controlled (e.g., 1-2 times per week).
Available Forms & Alternatives
Available Strengths:
Dosing & Administration
Adult Dosing
Standard Dose:
Apply to affected area at bedtime, once daily. Wash off in the morning. Reduce frequency to 1-2 times per week once sweating is controlled.
Condition-Specific Dosing:
hyperhidrosis:
Apply nightly until sweating is controlled, then 1-2 times per week as needed.
Pediatric Dosing
Neonatal:
Not established
Infant:
Not established
Child:
Use with caution and under medical supervision; generally not recommended for very young children.
Adolescent:
Similar to adult dosing, apply at bedtime, once daily initially, then reduce frequency.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Dialysis:
No specific considerations, minimal systemic absorption.
Hepatic Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Pharmacology
Mechanism of Action
Aluminum chloride hexahydrate works by forming a physical plug within the sweat ducts, which prevents sweat from reaching the skin surface. The aluminum salts react with electrolytes in the sweat to form a precipitate that blocks the sweat glands. Over time, the cells lining the sweat ducts swell and compress the ducts, further reducing sweat flow.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption (<1%)
Tmax:
Not applicable (topical)
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable (local action)
ProteinBinding:
Not applicable (local action)
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable (minimal systemic absorption)
Clearance:
Not applicable (minimal systemic absorption)
ExcretionRoute:
Not applicable (minimal systemic absorption)
Unchanged:
Not applicable (minimal systemic absorption)
Pharmacodynamics
OnsetOfAction:
Within 24-48 hours, full effect within 1-2 weeks of consistent use.
PeakEffect:
1-2 weeks
DurationOfAction:
Several days to a week after initial control, depending on individual and frequency of application.
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
If you experience any of the following severe side effects, contact your doctor immediately or seek emergency medical attention. Although rare, some individuals may be at risk for life-threatening reactions. Be aware of the following signs and symptoms:
Allergic reactions, characterized by:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Difficulty breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Irritation at the site where the medication was applied
Other Possible Side Effects
As with all medications, side effects can occur. While many people may not experience any side effects or only minor ones, it's essential to monitor your response to the medication. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Itching
Burning or stinging
* Prickling
Note: This list is not exhaustive, and you may experience other side effects not mentioned here. If you have concerns or questions about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice and support to manage any side effects you may be experiencing.
If you experience any of the following severe side effects, contact your doctor immediately or seek emergency medical attention. Although rare, some individuals may be at risk for life-threatening reactions. Be aware of the following signs and symptoms:
Allergic reactions, characterized by:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin (with or without fever)
+ Wheezing
+ Tightness in the chest or throat
+ Difficulty breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Irritation at the site where the medication was applied
Other Possible Side Effects
As with all medications, side effects can occur. While many people may not experience any side effects or only minor ones, it's essential to monitor your response to the medication. If you experience any of the following side effects or any other unusual symptoms that bother you or persist, contact your doctor for guidance:
Itching
Burning or stinging
* Prickling
Note: This list is not exhaustive, and you may experience other side effects not mentioned here. If you have concerns or questions about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice and support to manage any side effects you may be experiencing.
Seek Immediate Medical Attention If You Experience:
- Severe skin irritation
- Persistent itching or burning
- Rash that spreads or worsens
- Allergic reaction (rare, but seek immediate medical attention if swelling, difficulty breathing, or severe rash occurs)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This information will help your doctor and pharmacist assess potential interactions between this medication and other substances you are taking.
* Any existing health problems, as this medication may interact with certain conditions.
To ensure your safety, it is crucial to verify that it is safe to take this medication with all your current medications and health conditions. Never start, stop, or adjust the dosage of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This information will help your doctor and pharmacist assess potential interactions between this medication and other substances you are taking.
* Any existing health problems, as this medication may interact with certain conditions.
To ensure your safety, it is crucial to verify that it is safe to take this medication with all your current medications and health conditions. Never start, stop, or adjust the dosage of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.
To avoid staining, take precautions to protect your clothing and fabrics when using this drug, as it may cause discoloration. Additionally, be aware that this medication may react with certain metals, potentially causing harm.
While using this drug, refrain from using other deodorants or antiperspirants to minimize potential interactions. In the event of accidental ingestion, seek immediate medical attention by calling a doctor or poison control center right away, as this medication can be harmful if swallowed.
If you are pregnant, planning to become pregnant, or are breast-feeding, it is crucial to discuss the benefits and risks of this medication with your doctor to ensure the best possible outcome for you and your baby.
To avoid staining, take precautions to protect your clothing and fabrics when using this drug, as it may cause discoloration. Additionally, be aware that this medication may react with certain metals, potentially causing harm.
While using this drug, refrain from using other deodorants or antiperspirants to minimize potential interactions. In the event of accidental ingestion, seek immediate medical attention by calling a doctor or poison control center right away, as this medication can be harmful if swallowed.
If you are pregnant, planning to become pregnant, or are breast-feeding, it is crucial to discuss the benefits and risks of this medication with your doctor to ensure the best possible outcome for you and your baby.
Overdose Information
Overdose Symptoms:
- Severe local skin irritation
- Chemical burns (if applied to wet or broken skin)
What to Do:
Discontinue use. Wash affected area thoroughly with soap and water. Apply a soothing cream (e.g., hydrocortisone 1%) if irritation persists. For accidental ingestion, seek medical attention or call Poison Control (1-800-222-1222). Systemic toxicity from topical application is highly unlikely.
Drug Interactions
Monitoring
Baseline Monitoring
Skin integrity
Rationale: To assess for pre-existing irritation or open wounds before application.
Timing: Prior to first application
Routine Monitoring
Skin irritation (redness, itching, burning)
Frequency: Daily during initial treatment, then as needed
Target: Absence of significant irritation
Action Threshold: If severe irritation occurs, discontinue use and consult a healthcare professional.
Symptom Monitoring
- Skin irritation
- Itching
- Burning sensation
- Redness
- Rash
Special Patient Groups
Pregnancy
Generally considered low risk due to minimal systemic absorption. However, use only if clearly needed and after consulting a healthcare professional.
Trimester-Specific Risks:
First Trimester:
Low risk, but caution advised.
Second Trimester:
Low risk.
Third Trimester:
Low risk.
Lactation
Considered low risk due to minimal systemic absorption. Unlikely to cause adverse effects in a breastfed infant. Avoid applying to areas where the infant may come into direct contact with the product.
Infant Risk:
Low
Pediatric Use
Use with caution and under medical supervision, especially in younger children, due to potential for skin irritation and lack of extensive safety data in this population. Often used in adolescents for hyperhidrosis.
Geriatric Use
No specific dose adjustments are necessary. Elderly patients may have more fragile skin, so monitor closely for irritation.
Clinical Information
Clinical Pearls
- Ensure skin is completely dry before application to minimize irritation. Using a hairdryer on a cool setting can help.
- Apply a thin layer; excessive application does not increase efficacy and may increase irritation.
- If irritation occurs, try applying less frequently or using a lower concentration product.
- For underarms, avoid shaving for at least 12-24 hours before application to prevent stinging.
- Can be used on hands, feet, and other areas prone to excessive sweating, not just underarms.
Alternative Therapies
- Other aluminum-based antiperspirants (e.g., lower concentration aluminum chloride, aluminum zirconium salts)
- Botulinum toxin injections (Botox) for severe hyperhidrosis
- Iontophoresis (for hands and feet)
- Oral anticholinergic medications (e.g., glycopyrrolate, oxybutynin) for generalized hyperhidrosis
- Surgical sympathectomy (for severe, refractory cases)
Cost & Coverage
Average Cost:
$15 - $30 per 35ml bottle
Generic Available:
Yes
Insurance Coverage:
Generally not covered by insurance as it is an over-the-counter (OTC) product.
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor for further evaluation and guidance. To ensure your safety and the effectiveness of your treatment, never share your medication with others or take someone else's medication. Some medications may come with additional patient information leaflets, so it is a good idea to consult with your pharmacist for more details. If you have any questions or concerns about your medication, do not hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider for clarification and guidance. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide crucial information, including the name of the medication taken, the amount, and the time it was taken, to facilitate prompt and appropriate treatment.