Calcium Carb 500mg Chewtablets
Overview
What is this medicine?
How to Use This Medicine
To get the most benefit from your medication, take it exactly as directed by your doctor. Carefully read all the information provided with your prescription and follow the instructions closely. When taking your medication, be sure to chew it thoroughly before swallowing.
Storing and Disposing of Your Medication
Keep your medication at room temperature in a dry location. Avoid storing it in the bathroom. This will help maintain its effectiveness and prevent degradation.
What to Do If You Miss a Dose
Since this medication is taken as needed, do not take it more frequently than prescribed by your doctor. If you have any questions or concerns about your dosage, consult with your doctor for guidance.
Lifestyle & Tips
- Chew tablets thoroughly before swallowing for best results.
- Follow dosing instructions carefully; do not exceed the recommended daily dose.
- If using as an antacid, take as symptoms occur. If using as a calcium supplement, take with food to enhance absorption.
- Drink a full glass of water after taking the tablets, especially if using for calcium supplementation.
- Avoid taking calcium carbonate at the same time as other medications, especially antibiotics (like tetracyclines or fluoroquinolones), iron supplements, or thyroid hormones. Separate doses by at least 2-4 hours.
- Maintain adequate fluid intake to help prevent constipation, a common side effect.
- Limit foods and drinks that trigger heartburn, such as spicy foods, fatty foods, caffeine, and alcohol.
- Elevate the head of your bed if heartburn is worse at night.
Available Forms & Alternatives
Available Strengths:
- Calcium Carb 1250mg/5ml Susp
- Calcium Chloride 10% Inj, 10ml
- Calcium Oyster Shell 500mg Tablets
- Calcium 500mg Tablets
- Calcium Acetate 667mg Capsules
- Calcium 600+d (400u) Tablets
- Calcium 600mg Tablets
- Calcium 600mg + D Tablets
- Calcium 500 W/vit D3 Tablets
- Calcium Citrate 250mg Tablets
- Calcium Antacid 500mg Chw Tablets
- Calcium Carb 500mg Chewtablets
- Calcium Acetate 667mg Tablets
- Calcium Carb 648mg Tablets
- Calcium 500mg W/ Vit D Chw Tablets
- Calcium Citrate W/ Vit D Tablets
- Calcium/d3 600mg-200iu Tablets
- Calcium 500mg Chewable Tablets
- Calcium Gluconate 10% Inj, 50ml
- Calcium Antacid 750mg Chw Tablets
- Calcium Citrate 200mg Tablets
- Calcium Citrate+d3 Tablets
- Calcium Gluconate 10% Inj, 10ml
- Calcium Glu/nacl 1gm/100ml Soln
- Cal Glu/nacl 2000mg/100ml Inj 100ml
- Cal Glu/nacl 1gm/50ml Inj, 50ml
- Calcium Gluc 100mg/ml Inj, 50ml
- Calcium Gluconate 10% Inj, 100ml
- Calcium Gluc 100mg/ml Inj, 100ml
- Calcium Gluc 100mg/ml Inj, 10ml
Dosing & Administration
Adult Dosing
Condition-Specific Dosing:
Pediatric Dosing
Dose Adjustments
Renal Impairment:
Hepatic Impairment:
Pharmacology
Mechanism of Action
Pharmacokinetics
Absorption:
Distribution:
Elimination:
Pharmacodynamics
Safety & Warnings
Side Effects
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention. Although rare, some people may have severe and potentially life-threatening side effects when taking this medication. Be aware of the following signs of a serious allergic reaction:
- Rash
- Hives
- Itching
- Red, swollen, blistered, or peeling skin (with or without fever)
- Wheezing
- Tightness in the chest or throat
- Trouble breathing, swallowing, or talking
- Unusual hoarseness
- Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you are bothered by any of the following side effects or if they do not go away, contact your doctor for advice:
- Constipation
Please note that this list is not exhaustive, and you may experience other side effects. If you have questions or concerns about side effects, consult your doctor.
Reporting Side Effects
For medical advice about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Severe stomach pain or cramping
- Black, tarry stools (may indicate bleeding)
- Vomiting blood or material that looks like coffee grounds
- Symptoms of hypercalcemia: nausea, vomiting, constipation, increased thirst, increased urination, muscle weakness, fatigue, confusion.
- Symptoms of kidney stones: severe back or side pain, blood in urine, painful urination.
Before Using This Medicine
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
If you have elevated calcium levels in your blood.
Additionally, this medication may interact with other health conditions or medications. Therefore, it is crucial to provide your doctor and pharmacist with a comprehensive list of:
All prescription and over-the-counter (OTC) medications you are taking
Any natural products or vitamins you are using
* Your existing health problems
To ensure your safety, do not start, stop, or modify the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication in combination with your other medications and health conditions.
Precautions & Cautions
When taking this medication, be aware that it may interfere with the absorption of other oral medications. To minimize potential interactions, your doctor may recommend taking other oral drugs at a different time than this medication. Discuss your medication regimen with your doctor to determine the best schedule.
If you are pregnant, planning to become pregnant, or are currently breast-feeding, notify your doctor. You and your doctor will need to carefully weigh the benefits and risks of this medication to both you and your baby to make an informed decision about its use.
Overdose Information
Overdose Symptoms:
- Severe constipation
- Nausea
- Vomiting
- Loss of appetite
- Unusual tiredness or weakness
- Frequent urination
- Increased thirst
- Muscle pain or weakness
- Bone pain
- Confusion
- Irregular heartbeats
- Kidney stones (with chronic overdose)
What to Do:
Immediately contact a poison control center (1-800-222-1222) or seek emergency medical attention. Treatment may involve hydration, diuretics, and monitoring of electrolyte levels.
Drug Interactions
Major Interactions
- Tetracyclines (e.g., doxycycline, minocycline): Calcium can chelate these antibiotics, significantly reducing their absorption. Separate administration by at least 2-4 hours.
- Fluoroquinolones (e.g., ciprofloxacin, levofloxacin): Calcium can chelate these antibiotics, significantly reducing their absorption. Separate administration by at least 2-6 hours.
Moderate Interactions
- Bisphosphonates (e.g., alendronate, risedronate): Calcium can interfere with their absorption. Separate administration by at least 30 minutes to 2 hours.
- Thyroid hormones (e.g., levothyroxine): Calcium can reduce levothyroxine absorption. Separate administration by at least 4 hours.
- Iron supplements: Calcium can reduce iron absorption. Separate administration by at least 2 hours.
- Digoxin: Hypercalcemia (from excessive calcium carbonate intake) can increase the risk of digoxin toxicity, especially in patients with renal impairment.
- Phenytoin: Calcium can reduce phenytoin absorption. Separate administration by at least 2-3 hours.
- Thiazide diuretics: Can decrease urinary calcium excretion, increasing the risk of hypercalcemia.
- Vitamin D analogs (e.g., calcitriol): Increase calcium absorption, potentially leading to hypercalcemia when co-administered with calcium supplements.
Minor Interactions
- Acid-suppressing agents (e.g., PPIs, H2 blockers): May reduce calcium carbonate solubility and absorption if taken chronically, as gastric acid is needed for dissolution.
Monitoring
Routine Monitoring
Frequency: Not typically needed for occasional antacid use. For chronic high-dose use or in patients with renal impairment, every 3-6 months or as clinically indicated.
Target: 8.5-10.5 mg/dL (2.1-2.6 mmol/L)
Action Threshold: Levels > 10.5 mg/dL (hypercalcemia) warrant dose reduction or discontinuation and investigation.
Frequency: For chronic high-dose use or in patients with pre-existing renal impairment, every 6-12 months or as clinically indicated.
Target: Normal ranges for age and sex
Action Threshold: Significant decline in renal function may necessitate dose adjustment or discontinuation due to increased hypercalcemia risk.
Frequency: Ongoing patient education and monitoring.
Target: Absence of symptoms
Action Threshold: Presence of symptoms like nausea, vomiting, constipation, polyuria, polydipsia, muscle weakness, fatigue, confusion.
Symptom Monitoring
- Heartburn relief
- Indigestion relief
- Constipation (common side effect)
- Nausea
- Vomiting
- Loss of appetite
- Unusual tiredness or weakness
- Frequent urination
- Increased thirst
- Muscle pain or weakness
- Confusion (signs of hypercalcemia)
Special Patient Groups
Pregnancy
Generally considered safe for use during pregnancy when taken at recommended doses for antacid or calcium supplementation. Calcium requirements increase during pregnancy, and calcium carbonate is a common source. Consult a healthcare provider before use.
Trimester-Specific Risks:
Lactation
Considered safe for use during lactation. Calcium is a normal component of breast milk, and maternal calcium carbonate use at recommended doses is not expected to harm the infant.
Pediatric Use
Use in children under 12 years should be under the guidance of a healthcare professional, especially for long-term use or for conditions other than occasional antacid relief. Dosing must be age-appropriate. Risk of constipation and potential for hypercalcemia with excessive use.
Geriatric Use
Use with caution in elderly patients, especially those with pre-existing renal impairment, due to an increased risk of hypercalcemia and constipation. Monitor renal function and serum calcium levels if used chronically or at higher doses.
Clinical Information
Clinical Pearls
- Calcium carbonate is most effective as an antacid when chewed thoroughly before swallowing.
- For optimal calcium absorption, take calcium carbonate with food.
- Separate calcium carbonate from other medications (especially antibiotics, iron, thyroid hormones) by at least 2-4 hours to prevent absorption interference.
- Chronic high-dose use can lead to constipation, hypercalcemia, and in rare cases, milk-alkali syndrome (especially with concomitant dairy intake or renal impairment).
- Patients with a history of kidney stones should use calcium carbonate cautiously and under medical supervision.
- Not recommended for long-term daily use as an antacid without medical advice, as it may mask underlying conditions.
Alternative Therapies
- Other antacids (e.g., aluminum hydroxide, magnesium hydroxide, sodium bicarbonate)
- H2-receptor antagonists (H2RAs) (e.g., famotidine, ranitidine - though ranitidine is largely off-market)
- Proton pump inhibitors (PPIs) (e.g., omeprazole, esomeprazole)
- Alginate-based products (e.g., Gaviscon)
- Dietary calcium sources (for supplementation)