Betamethasone Dip 0.05% Lotn 60ml

Betamethasone dipropionate is a high-potency synthetic corticosteroid. It induces phospholipase A2 inhibitory proteins, collectively called lipocortins. These proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Betamethasone also exhibits vasoconstrictive, antipruritic, and anti-inflammatory actions.

Urgent Side Effects: Seek Medical Help Right Away

While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of a weak adrenal gland, including:
+ Severe upset stomach or vomiting
+ Severe dizziness or fainting
+ Muscle weakness
+ Feeling extremely tired
+ Mood changes
+ Decreased appetite
+ Weight loss
Signs of Cushing's syndrome, such as:
+ Weight gain in the upper back or belly
+ Moon face
+ Severe headache
+ Slow healing
Signs of high blood sugar, including:
+ Confusion
+ Feeling sleepy
+ Unusual thirst or hunger
+ Passing urine more often
+ Flushing
+ Fast breathing
+ Breath that smells like fruit
Skin changes, such as:
+ Pimples
+ Stretch marks
+ Slow healing
+ Hair growth
Skin irritation
Thinning of the skin
Changes in eyesight

Other Possible Side Effects

Like all medications, this drug can cause side effects. Many people experience no side effects or only mild ones. If you notice any of the following side effects or any other unusual symptoms, contact your doctor or seek medical help if they bother you or do not go away:

Burning or stinging
Dry skin
* Itching

This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
If you have thinning skin at the site where you will be applying this medication.

This list is not exhaustive, and it is crucial to discuss all your medications (including prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine whether it is safe to take this medication in conjunction with your other medications and health issues.

Remember, do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor to ensure your safety.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Adhere to the prescribed duration of use and do not exceed it without consulting your doctor.

When applying this medication to a large skin area, exercise caution and discuss it with your doctor. Additionally, this medication is not intended for treating diaper rash or redness, and it is crucial to avoid applying it to the diaper area.

Be aware that using this medication may increase the risk of developing cataracts or glaucoma. Consult your doctor to discuss this potential risk. In some cases, this medication may affect growth in children and teenagers, and regular growth checks may be necessary. Your doctor will determine if growth monitoring is required.

When administering this medication to a child, use it with caution, as the risk of certain side effects may be higher in children. Different brands of this medication may be suitable for different age groups, so consult your doctor before giving it to a child.

If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor. It is necessary to discuss the benefits and risks of using this medication during these situations. If you are breastfeeding, avoid applying this medication directly to the nipple or the surrounding area.

• Burning
• Itching
• Irritation
• Dryness
• Folliculitis
• Hypertrichosis
• Acneiform eruptions
• Hypopigmentation
• Perioral dermatitis
• Allergic contact dermatitis
• Maceration of the skin
• Secondary infection
• Skin atrophy
• Striae
• Miliaria
• Unusual weight gain
• Swelling in ankles/feet
• Increased thirst/urination (signs of hyperglycemia)
• Fatigue
• Weakness

Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Avoid large areas, prolonged use, or occlusive dressings.

Use with caution. It is not known whether topical corticosteroids are excreted in human milk. Systemic corticosteroids are excreted into breast milk. Avoid applying to the breast area to prevent infant ingestion.

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio. Use the lowest effective dose for the shortest duration possible. Not recommended for children under 12 years for some formulations.

No specific dose adjustments are generally needed. However, geriatric patients may have thinner skin, which could increase susceptibility to local adverse effects such as skin atrophy, purpura, and striae. Use with caution and monitor for skin integrity.

• Betamethasone dipropionate 0.05% lotion is a high-potency topical corticosteroid. It should be used judiciously and typically for short durations (e.g., 2 weeks) to minimize the risk of local and systemic side effects.
• Patients should be instructed on the correct application technique: a thin film, gently rubbed in, avoiding excessive amounts or prolonged use.
• Avoid using this high-potency steroid on the face, groin, or axillae unless specifically directed by a dermatologist, as these areas are more prone to adverse effects like skin atrophy, telangiectasias, and perioral dermatitis.
• Abrupt discontinuation after prolonged use on large body surface areas can lead to a rebound flare of the underlying dermatosis. Tapering may be necessary in such cases.
• Educate patients on signs of local adverse effects (e.g., skin thinning, stretch marks) and systemic absorption (e.g., unusual weight gain, swelling).

• Other topical corticosteroids of varying potencies (e.g., clobetasol propionate, fluocinonide, triamcinolone acetonide, hydrocortisone)
• Topical calcineurin inhibitors (e.g., tacrolimus, pimecrolimus) for eczema, especially on sensitive areas.
• Topical PDE4 inhibitors (e.g., crisaborole) for eczema.
• Systemic therapies (e.g., biologics, oral immunosuppressants) for severe, widespread, or refractory dermatoses.
• Emollients and moisturizers for barrier repair and symptom management.

If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist. If you have any questions or concerns about this medication, don't hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the medication taken, the amount, and the time it occurred.