Betamethasone Dip 0.05% Aug Crm 50g

Betamethasone dipropionate is a high-potency synthetic corticosteroid. It exerts its anti-inflammatory, antipruritic, and vasoconstrictive actions by inducing phospholipase A2 inhibitory proteins (lipocortins). These proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.

Urgent Side Effects: Seek Medical Help Right Away

While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention immediately:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of a weak adrenal gland, including:
+ Severe upset stomach or vomiting
+ Severe dizziness or fainting
+ Muscle weakness
+ Feeling extremely tired
+ Mood changes
+ Decreased appetite
+ Weight loss
Signs of Cushing's syndrome, such as:
+ Weight gain in the upper back or belly
+ Moon face
+ Severe headache
+ Slow healing
Signs of high blood sugar, including:
+ Confusion
+ Feeling sleepy
+ Unusual thirst or hunger
+ Passing urine more often
+ Flushing
+ Fast breathing
+ Breath that smells like fruit
Skin changes, such as:
+ Pimples
+ Stretch marks
+ Slow healing
+ Hair growth
Skin irritation
Thinning of the skin
Changes in eyesight

Other Possible Side Effects

Like all medications, this drug can cause side effects. Many people experience no side effects or only mild ones. If you notice any of the following side effects or any other unusual symptoms, contact your doctor or seek medical attention if they bother you or do not go away:

Burning or stinging
Dry skin
* Itching

This is not a comprehensive list of all possible side effects. If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you have thinning of the skin in the area where you will be applying this medication.

This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. Additionally, share any health problems you have to ensure safe use of this medication.

To guarantee your safety, do not start, stop, or change the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication with all your other medications and health conditions.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Adhere to the prescribed duration of use and do not exceed it without consulting your doctor.

When applying this medication to a large skin area, exercise caution and discuss it with your doctor. Additionally, avoid using this medication to treat diaper rash or redness, and refrain from applying it to the diaper area.

Be aware that this medication may increase the risk of developing cataracts or glaucoma. Consult your doctor to discuss this potential risk. In children and teenagers, this medication may affect growth in some cases, necessitating regular growth checks. Consult your doctor to determine the best course of action.

When administering this medication to a child, use it with caution, as the risk of certain side effects may be higher in this age group. Note that different brands of this medication may be suitable for different age groups, so consult your doctor before giving it to a child.

If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. It is crucial to discuss the benefits and risks of this medication to both you and your baby. If you are breastfeeding, avoid applying this medication directly to the nipple or the surrounding area.

• Not significant with typical topical use.

• Not significant with typical topical use.

• Not significant with typical topical use.

• Not significant with typical topical use.

• Worsening of skin condition
• New skin lesions or infections
• Excessive burning, itching, or irritation at application site
• Thinning of skin, easy bruising, or stretch marks (striae)
• Increased hair growth at application site
• Signs of systemic effects: unusual weight gain, facial puffiness (moon face), fatigue, muscle weakness, increased thirst/urination (hyperglycemia).

Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Corticosteroids have been shown to be teratogenic in animals. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Caution should be exercised when Betamethasone Dipropionate Augmented Cream is administered to a nursing woman.

Children are more susceptible to systemic toxicity from topical corticosteroids due to their larger skin surface area to body weight ratio. HPA axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Not recommended for children under 12 years of age. If used, limit to the smallest amount for the shortest duration.

No specific dose adjustments are required. However, elderly patients may have thinner skin, which could potentially increase systemic absorption or increase the risk of local adverse effects like skin atrophy. Monitor for skin fragility.

• Betamethasone Dipropionate Augmented 0.05% Cream is a high-potency topical corticosteroid. Use it sparingly and for short durations (typically up to 2 weeks) to minimize side effects.
• Avoid using this cream on the face, groin, or axillae unless specifically instructed by a dermatologist, as these areas are more prone to skin thinning and other adverse effects.
• Do not use occlusive dressings (e.g., bandages, plastic wrap) over the treated area unless directed by your healthcare provider, as this significantly increases systemic absorption.
• Educate patients on the signs of skin atrophy (thinning, bruising, striae) and systemic absorption (e.g., moon face, weight gain) and to report these to their doctor.
• This formulation is 'augmented' for enhanced penetration, making it more potent than non-augmented betamethasone dipropionate creams.

• Medium-potency topical corticosteroids (e.g., Triamcinolone Acetonide 0.1% Cream/Ointment)
• Low-potency topical corticosteroids (e.g., Hydrocortisone 1% Cream/Ointment)
• Topical calcineurin inhibitors (e.g., Tacrolimus ointment, Pimecrolimus cream) for steroid-sparing therapy, especially on sensitive areas.
• Vitamin D analogs (e.g., Calcipotriene) for psoriasis.
• Systemic therapies (e.g., biologics, oral immunosuppressants) for severe, widespread conditions.

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist. If you have any questions or concerns about this medication, don't hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the medication taken, the amount, and the time it occurred.