Zinc Oxide 20% Ointment 30gm
It is used to treat or prevent diaper rash.It is used to treat skin irritation.It is used to treat poison oak, ivy, and sumac rashes.It may be given to you for other reasons. Talk with the doctor.
Drug Class
Topical skin protectant
Pharmacologic Class
Astringent; Barrier cream
Pregnancy Category
Not applicable (minimal systemic absorption)
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Zinc oxide ointment is a skin protectant that forms a barrier on your skin to help prevent and heal minor skin irritations like diaper rash, chafing, and minor cuts or burns. It helps to keep moisture away from the skin and allows it to heal.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication as directed.
Application Instructions
Do not take this medication by mouth. It is for topical use on your skin only.
Avoid getting the medication in your mouth, nose, or eyes, as it may cause burning.
Wash your hands before and after applying the medication, unless your hand is the treated area, in which case you should not wash it after application.
Clean the affected area before use and dry it thoroughly.
Apply the medication to the affected area and gently rub it in.
Special Instructions for Diaper Use
If you are using this medication on a diapered area, change the diaper frequently.
Clean the affected area and allow it to dry before reapplying the medication.
Apply the medication with each diaper change, especially at bedtime.
Storage and Disposal
Store this medication at room temperature in a dry place, avoiding storage in a bathroom.
Keep all medications in a safe location, out of the reach of children and pets.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not apply it more frequently than directed by your doctor.
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication as directed.
Application Instructions
Do not take this medication by mouth. It is for topical use on your skin only.
Avoid getting the medication in your mouth, nose, or eyes, as it may cause burning.
Wash your hands before and after applying the medication, unless your hand is the treated area, in which case you should not wash it after application.
Clean the affected area before use and dry it thoroughly.
Apply the medication to the affected area and gently rub it in.
Special Instructions for Diaper Use
If you are using this medication on a diapered area, change the diaper frequently.
Clean the affected area and allow it to dry before reapplying the medication.
Apply the medication with each diaper change, especially at bedtime.
Storage and Disposal
Store this medication at room temperature in a dry place, avoiding storage in a bathroom.
Keep all medications in a safe location, out of the reach of children and pets.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not apply it more frequently than directed by your doctor.
Lifestyle & Tips
- Keep the affected skin area clean and dry before applying the ointment.
- Apply a thick layer to ensure adequate protection.
- For diaper rash, change diapers frequently and apply at each diaper change, especially at bedtime.
Available Forms & Alternatives
Available Strengths:
- Zinc Sulfate 220mg Capsules
- Zinc Trace 1mg/ml Inj, 10ml
- Zinc Oxide 20% Ointment 56.7gm
- Zinc Oxide 20% Ointment 28.4gm
- Zinc Sulfate 5mg/ml Inj, 5ml
- Zinc 50mg Tablets
- Zinc Sulfate 220mg Tablets
- Zinc Oxide 20% Ointment 30gm
- Zinc Oxide 20% Ointment 425gm
- Zinc Oxide Ointment 454gm
- Zinc Oxide 20% Ointment 60gm
- Zinc Sulfate 10mg/10ml Inj, 10ml
- Zinc Sulfate 220mg Capsules
- Zinc Sulfate 5mg/ml Inj, 5ml
- Zinc Sulfate 10mg/10ml Inj, 10ml
- Zinc Chloride 10mg/10ml Inj, 10ml
- Zinc Sulfate 3mg/ml Inj, 10ml
- Zinc Sulfate 3mg/ml Inj, 10ml
Dosing & Administration
Adult Dosing
Standard Dose:
Apply topically to affected area as needed, typically 2-4 times daily.
Condition-Specific Dosing:
diaperRash:
Cleanse the diaper area and allow to dry. Apply ointment liberally as often as necessary, with each diaper change, especially at bedtime or any time when exposure to wet diapers may be prolonged.
minorSkinIrritations:
Apply a thin layer to the affected area as needed.
Pediatric Dosing
Neonatal:
Apply topically to affected area as needed, typically 2-4 times daily. Safe for use in neonates for diaper rash.
Infant:
Apply topically to affected area as needed, typically 2-4 times daily. Safe for use in infants for diaper rash.
Child:
Apply topically to affected area as needed, typically 2-4 times daily.
Adolescent:
Apply topically to affected area as needed, typically 2-4 times daily.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed (minimal systemic absorption).
Moderate:
No adjustment needed (minimal systemic absorption).
Severe:
No adjustment needed (minimal systemic absorption).
Dialysis:
No specific considerations (minimal systemic absorption).
Hepatic Impairment:
Mild:
No adjustment needed (minimal systemic absorption).
Moderate:
No adjustment needed (minimal systemic absorption).
Severe:
No adjustment needed (minimal systemic absorption).
Pharmacology
Mechanism of Action
Zinc oxide acts as a topical skin protectant by forming a physical barrier on the skin surface, which helps to prevent irritation and moisture loss. It also possesses mild astringent and antiseptic properties, aiding in the drying of oozing and weeping from minor skin irritations and promoting healing.
Pharmacokinetics
Absorption:
Bioavailability:
Negligible systemic absorption
Tmax:
Not applicable (topical, local action)
FoodEffect:
Not applicable (topical)
Distribution:
Vd:
Not applicable (minimal systemic absorption)
ProteinBinding:
Not applicable (minimal systemic absorption)
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable (minimal systemic absorption)
Clearance:
Not applicable (minimal systemic absorption)
ExcretionRoute:
Not applicable (minimal systemic absorption)
Unchanged:
Not applicable (minimal systemic absorption)
Pharmacodynamics
OnsetOfAction:
Immediate (upon application, forms physical barrier)
PeakEffect:
Not applicable (continuous local action)
DurationOfAction:
Until removed or rubbed off (reapplication needed as per irritation)
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek immediate medical attention:
* Signs of an allergic reaction, including:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, discuss them with your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice on managing side effects.
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek immediate medical attention:
* Signs of an allergic reaction, including:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Other Possible Side Effects
Like all medications, this drug can cause side effects. However, many people do not experience any side effects or only have mild ones. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, discuss them with your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch. Your doctor can provide medical advice on managing side effects.
Seek Immediate Medical Attention If You Experience:
- Increased redness, swelling, or pain at the application site.
- Signs of infection (e.g., pus, fever).
- Allergic reaction (e.g., severe rash, itching, hives, difficulty breathing - seek immediate medical attention).
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you have a deep wound or a puncture wound, as this may affect your ability to take this medication.
This is not an exhaustive list of potential interactions. Therefore, it is crucial to discuss all of your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. Additionally, share any health problems you are experiencing to ensure safe treatment.
To guarantee your safety, do not start, stop, or modify the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication in conjunction with your other medications and health conditions.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you have a deep wound or a puncture wound, as this may affect your ability to take this medication.
This is not an exhaustive list of potential interactions. Therefore, it is crucial to discuss all of your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. Additionally, share any health problems you are experiencing to ensure safe treatment.
To guarantee your safety, do not start, stop, or modify the dosage of any medication without first consulting your doctor. It is vital to verify that it is safe to take this medication in conjunction with your other medications and health conditions.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Adhere strictly to the prescribed dosage and duration of treatment, and do not use this drug more frequently or for an extended period than recommended.
To avoid staining, take precautions to protect your clothing and fabrics when using this medication, as it may cause discoloration.
In the event of accidental ingestion, this drug can be harmful. If swallowed, immediately contact a doctor or a poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breastfeeding, notify your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision.
To avoid staining, take precautions to protect your clothing and fabrics when using this medication, as it may cause discoloration.
In the event of accidental ingestion, this drug can be harmful. If swallowed, immediately contact a doctor or a poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breastfeeding, notify your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision.
Overdose Information
Overdose Symptoms:
- Topical overdose is highly unlikely and generally not associated with systemic toxicity due to minimal absorption.
- Excessive application may lead to a thick, greasy residue.
What to Do:
Wipe off excess ointment. If ingested, contact a poison control center (1-800-222-1222) or seek medical attention, though systemic toxicity from topical zinc oxide is rare.
Drug Interactions
Monitoring
Symptom Monitoring
- Monitor for improvement in skin irritation or rash.
- Monitor for signs of worsening irritation, redness, swelling, or infection.
- Monitor for allergic reactions (e.g., rash, itching, hives).
Special Patient Groups
Pregnancy
Generally considered safe for use during pregnancy due to minimal systemic absorption. Consult a healthcare provider if concerns arise.
Trimester-Specific Risks:
First Trimester:
No known risks.
Second Trimester:
No known risks.
Third Trimester:
No known risks.
Lactation
Generally considered safe for use during breastfeeding due to minimal systemic absorption. Avoid applying to the nipple area if breastfeeding, or wipe off before nursing to prevent infant ingestion.
Infant Risk:
Low risk (L1)
Pediatric Use
Safe and commonly used in all pediatric age groups, including neonates, for conditions like diaper rash. No specific dose adjustments needed.
Geriatric Use
Safe for use in geriatric patients. No specific dose adjustments needed. May be beneficial for skin folds and pressure areas.
Clinical Information
Clinical Pearls
- Zinc oxide ointment is a staple for diaper rash prevention and treatment due to its barrier properties.
- It can be used for various minor skin irritations, chafing, and as a mild sunscreen (though 20% may not be sufficient for primary sun protection).
- Ensure the skin is clean and dry before application for best results.
- A thick layer is often more effective than a thin one for barrier protection.
- Can be messy; consider wearing gloves during application or washing hands thoroughly afterward.
Alternative Therapies
- Petrolatum (Vaseline)
- Lanolin
- Dimethicone-based barrier creams
- Calamine lotion (for drying weeping lesions)
- Hydrocortisone cream (for inflammatory rashes, under medical supervision)
Cost & Coverage
Average Cost:
$5 - $15 per 30gm tube
Generic Available:
Yes
Insurance Coverage:
Typically OTC, not covered by most insurance plans unless prescribed for specific medical necessity.
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.