Vitafol Strips
This vitamin is used to aid the diet needs before, during, and after pregnancy.
Drug Class
Nutritional Supplement; Vitamin/Mineral Supplement
Pharmacologic Class
Multivitamin/Mineral Combination
Pregnancy Category
Not applicable (designed for use in pregnancy)
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Vitafol Strips are a type of prenatal vitamin that comes in a dissolvable strip form. They are designed to provide essential vitamins and minerals, like folic acid, iron, and DHA, that are important for you and your baby's health during pregnancy and while breastfeeding.
How to Use This Medicine
Taking Your Medication Correctly
To ensure you get the most benefit from your medication, follow these steps:
1. Follow Your Doctor's Orders: Take your medication exactly as directed by your doctor. Read all the information provided with your medication and follow the instructions carefully.
2. Proper Administration: Place the oral strip on your tongue and allow it to dissolve.
3. Food and Water: Some medications need to be taken with food or on an empty stomach. Check with your pharmacist to determine the best approach for your specific medication. Take your medication with a full glass of water.
4. Avoid Interactions: Do not take antacids within 2 hours before or 2 hours after taking your medication. Additionally, avoid taking dairy products with your medication, as they may reduce its effectiveness.
5. Timing with Other Medications: If you take other medications by mouth, consult with your doctor or pharmacist to determine if you need to take them at a different time than your current medication.
Storing and Disposing of Your Medication
To maintain the quality and safety of your medication:
1. Store at Room Temperature: Keep your medication at room temperature, protected from light and moisture.
2. Protect from Heat: Avoid storing your medication in areas with high temperatures, such as bathrooms or near heating vents.
3. Secure Storage: Keep all medications in a safe place, out of the reach of children and pets.
Missing a Dose
If you miss a dose:
1. Take as Soon as Possible: Take the missed dose as soon as you remember.
2. Skip if Close to Next Dose: If it's close to the time for your next dose, skip the missed dose and resume your regular schedule.
3. Avoid Double Dosing: Do not take two doses at the same time or take extra doses to make up for a missed dose.
To ensure you get the most benefit from your medication, follow these steps:
1. Follow Your Doctor's Orders: Take your medication exactly as directed by your doctor. Read all the information provided with your medication and follow the instructions carefully.
2. Proper Administration: Place the oral strip on your tongue and allow it to dissolve.
3. Food and Water: Some medications need to be taken with food or on an empty stomach. Check with your pharmacist to determine the best approach for your specific medication. Take your medication with a full glass of water.
4. Avoid Interactions: Do not take antacids within 2 hours before or 2 hours after taking your medication. Additionally, avoid taking dairy products with your medication, as they may reduce its effectiveness.
5. Timing with Other Medications: If you take other medications by mouth, consult with your doctor or pharmacist to determine if you need to take them at a different time than your current medication.
Storing and Disposing of Your Medication
To maintain the quality and safety of your medication:
1. Store at Room Temperature: Keep your medication at room temperature, protected from light and moisture.
2. Protect from Heat: Avoid storing your medication in areas with high temperatures, such as bathrooms or near heating vents.
3. Secure Storage: Keep all medications in a safe place, out of the reach of children and pets.
Missing a Dose
If you miss a dose:
1. Take as Soon as Possible: Take the missed dose as soon as you remember.
2. Skip if Close to Next Dose: If it's close to the time for your next dose, skip the missed dose and resume your regular schedule.
3. Avoid Double Dosing: Do not take two doses at the same time or take extra doses to make up for a missed dose.
Lifestyle & Tips
- Take one strip daily as directed, preferably with food to minimize stomach upset.
- Do not exceed the recommended dose.
- Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins.
- Stay hydrated by drinking plenty of water.
- Discuss any other supplements or medications you are taking with your healthcare provider to avoid interactions.
- Store strips at room temperature, away from moisture and direct light.
Available Forms & Alternatives
Dosing & Administration
Adult Dosing
Standard Dose:
One Vitafol Strip orally once daily
Dose Range:
1 - 1 mg
Condition-Specific Dosing:
pregnancy:
One strip orally once daily
lactation:
One strip orally once daily
Pediatric Dosing
Neonatal:
Not established (not indicated for direct pediatric use)
Infant:
Not established (not indicated for direct pediatric use)
Child:
Not established (not indicated for direct pediatric use)
Adolescent:
Not established (not indicated for direct pediatric use, unless pregnant/lactating)
Dose Adjustments
Renal Impairment:
Mild:
Not typically adjusted for general supplementation; consult physician for specific deficiencies/toxicities.
Moderate:
Not typically adjusted for general supplementation; consult physician for specific deficiencies/toxicities.
Severe:
Not typically adjusted for general supplementation; consult physician for specific deficiencies/toxicities.
Dialysis:
Consideration for specific nutrient levels (e.g., iron, vitamin D) may be needed; consult nephrologist.
Hepatic Impairment:
Mild:
Not typically adjusted for general supplementation.
Moderate:
Not typically adjusted for general supplementation.
Severe:
Not typically adjusted for general supplementation.
Pharmacology
Mechanism of Action
Vitafol Strips provide essential vitamins and minerals (e.g., folic acid, iron, vitamin D, DHA) necessary to meet the increased nutritional demands during pregnancy and lactation, supporting maternal health and optimal fetal/infant development. Folic acid is crucial for neural tube development, iron for red blood cell formation and oxygen transport, and DHA for brain and eye development.
Pharmacokinetics
Absorption:
Bioavailability:
Highly variable depending on the specific nutrient and its formulation (e.g., iron absorption is regulated, fat-soluble vitamins require dietary fat).
Tmax:
Not applicable for a multi-nutrient combination; varies by individual component.
FoodEffect:
Absorption of some components (e.g., iron) may be affected by food; some fat-soluble vitamins require fat for optimal absorption. Follow product-specific instructions.
Distribution:
Vd:
Not applicable for a multi-nutrient combination; nutrients are distributed throughout the body to tissues and cells where they are utilized for metabolic processes, growth, and repair.
ProteinBinding:
Variable depending on the specific nutrient (e.g., vitamin D binds to vitamin D-binding protein).
CnssPenetration:
Limited for most components, but specific nutrients (e.g., DHA) are crucial for CNS development.
Elimination:
HalfLife:
Not applicable for a multi-nutrient combination; varies by individual component.
Clearance:
Not applicable for a multi-nutrient combination; varies by individual component.
ExcretionRoute:
Excretion routes vary by nutrient (e.g., water-soluble vitamins primarily via urine, some minerals via feces); excess amounts are typically excreted.
Unchanged:
Variable depending on the specific nutrient.
Pharmacodynamics
OnsetOfAction:
Not applicable for a nutritional supplement in the same way as a pharmacologically active drug. Therapeutic effects are achieved through sustained provision of essential nutrients, supporting physiological processes over time.
PeakEffect:
Not applicable for a nutritional supplement.
DurationOfAction:
Not applicable for a nutritional supplement; benefits are sustained with consistent daily intake.
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention, as they may be signs of a severe and potentially life-threatening reaction:
- Signs of an allergic reaction, such as rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Other Possible Side Effects
While many people taking this medication may not experience any side effects or only minor ones, it's essential to be aware of the following:
- Gastrointestinal issues: constipation, diarrhea, stomach pain, upset stomach, or vomiting
- Heartburn
What to Do If You Experience Side Effects
If any of these side effects or any others bother you or do not go away, contact your doctor for advice. Not all possible side effects are listed here. If you have questions or concerns about side effects, discuss them with your doctor.
Reporting Side Effects
To report side effects, you can contact the FDA at 1-800-332-1088 or visit their website at https://www.fda.gov/medwatch. Your doctor is also a valuable resource for guidance on managing side effects.
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention, as they may be signs of a severe and potentially life-threatening reaction:
- Signs of an allergic reaction, such as rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Other Possible Side Effects
While many people taking this medication may not experience any side effects or only minor ones, it's essential to be aware of the following:
- Gastrointestinal issues: constipation, diarrhea, stomach pain, upset stomach, or vomiting
- Heartburn
What to Do If You Experience Side Effects
If any of these side effects or any others bother you or do not go away, contact your doctor for advice. Not all possible side effects are listed here. If you have questions or concerns about side effects, discuss them with your doctor.
Reporting Side Effects
To report side effects, you can contact the FDA at 1-800-332-1088 or visit their website at https://www.fda.gov/medwatch. Your doctor is also a valuable resource for guidance on managing side effects.
Seek Immediate Medical Attention If You Experience:
- Severe stomach pain or cramping
- Persistent nausea or vomiting
- Severe constipation or diarrhea
- Allergic reaction symptoms (rash, itching, swelling, severe dizziness, trouble breathing)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain types of anemia, particularly those characterized by a vitamin B12 deficiency, such as pernicious anemia.
* If you are currently taking levodopa.
This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. They will help you determine if it is safe to take this medication in conjunction with your other medications and health conditions.
Remember, do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor to ensure your safety.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain types of anemia, particularly those characterized by a vitamin B12 deficiency, such as pernicious anemia.
* If you are currently taking levodopa.
This list is not exhaustive, and it is crucial to discuss all your medications, including prescription and over-the-counter drugs, natural products, and vitamins, with your doctor and pharmacist. They will help you determine if it is safe to take this medication in conjunction with your other medications and health conditions.
Remember, do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor to ensure your safety.
Precautions & Cautions
It is essential to inform all of your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This drug may interfere with certain laboratory tests, so be sure to notify all of your healthcare providers and laboratory personnel that you are taking this medication. If you are breastfeeding, consult your doctor to discuss the potential risks to your baby and determine the best course of action.
Overdose Information
Overdose Symptoms:
- Severe nausea and vomiting
- Diarrhea
- Abdominal pain
- Black, tarry stools (due to iron toxicity)
- Weakness
- Dizziness
- Rapid heart rate
- Bluish lips or fingernails (in severe iron overdose)
- Confusion
- Seizures
What to Do:
Seek immediate medical attention or call Poison Control (1-800-222-1222). Iron overdose can be life-threatening, especially in children.
Drug Interactions
Major Interactions
- Levothyroxine (iron can decrease absorption; separate administration by at least 4 hours)
- Tetracycline antibiotics (iron/calcium can chelate and reduce absorption; separate administration by 2-4 hours)
- Fluoroquinolone antibiotics (iron/calcium can chelate and reduce absorption; separate administration by 2-4 hours)
Moderate Interactions
- Antacids (may decrease iron absorption; separate administration)
- Proton pump inhibitors (PPIs) / H2 blockers (may decrease absorption of some minerals like iron due to reduced stomach acid)
- Bisphosphonates (calcium can interfere with absorption; separate administration)
- Thyroid hormones (iron can interfere with absorption; separate administration)
- Certain diuretics (e.g., thiazides may increase calcium reabsorption, loop diuretics may increase calcium excretion)
Minor Interactions
- Dietary fiber (may reduce iron absorption)
- Caffeine (may reduce iron absorption)
Monitoring
Baseline Monitoring
Complete Blood Count (CBC) with ferritin
Rationale: To assess for pre-existing anemia or iron deficiency, which is common in pregnancy.
Timing: Prior to or early in pregnancy.
Vitamin D levels (25-hydroxyvitamin D)
Rationale: To assess for vitamin D deficiency, which is common and important for bone health and fetal development.
Timing: Prior to or early in pregnancy, especially in at-risk populations.
General nutritional status
Rationale: To identify any significant dietary deficiencies or excesses.
Timing: Initial consultation.
Routine Monitoring
Adherence to daily dosing
Frequency: Ongoing
Target: Consistent daily intake
Action Threshold: Inconsistent use may lead to suboptimal nutrient levels; reinforce importance.
Symptoms of gastrointestinal upset (nausea, constipation)
Frequency: Ongoing
Target: Minimal to no symptoms
Action Threshold: Significant symptoms may require dietary adjustments, timing changes, or alternative formulations.
Iron levels (if initial anemia or risk factors)
Frequency: As clinically indicated by physician (e.g., mid-pregnancy)
Target: Within normal limits for pregnancy
Action Threshold: Persistent anemia may require additional iron supplementation or investigation.
Symptom Monitoring
- Nausea
- Constipation
- Diarrhea
- Stomach upset
- Dark stools (due to iron)
- Allergic reactions (rare)
Special Patient Groups
Pregnancy
Vitafol Strips are specifically formulated and indicated for use during pregnancy to support maternal health and fetal development. They provide crucial nutrients like folic acid to prevent neural tube defects, iron to prevent anemia, and DHA for brain and eye development.
Trimester-Specific Risks:
First Trimester:
Essential for neural tube development (folic acid) and early organogenesis. No known risks when taken at recommended doses.
Second Trimester:
Supports continued fetal growth and maternal blood volume expansion. No known risks when taken at recommended doses.
Third Trimester:
Supports rapid fetal growth, bone development (vitamin D, calcium), and preparation for delivery. No known risks when taken at recommended doses.
Lactation
Vitafol Strips are indicated for use during lactation to help meet the increased nutritional demands of breastfeeding mothers and to support nutrient transfer to breast milk for infant development.
Infant Risk:
L1 (Safest) - Components are essential nutrients and are considered safe and beneficial for the breastfed infant when taken at recommended doses.
Pediatric Use
Not indicated for direct pediatric use. The product is designed for adults of childbearing age, specifically pregnant and lactating women.
Geriatric Use
Not specifically formulated for geriatric populations. While some components may be beneficial, specific geriatric vitamin/mineral needs differ from prenatal needs.
Clinical Information
Clinical Pearls
- Emphasize the critical role of folic acid in preventing neural tube defects, especially if taken prior to conception and throughout the first trimester.
- Advise patients that iron in prenatal vitamins can cause constipation and dark stools; recommend increasing fluid and fiber intake.
- Vitafol Strips offer an alternative for patients who have difficulty swallowing pills.
- Remind patients that prenatal vitamins are supplements and do not replace a healthy, balanced diet.
- Counsel on potential drug-nutrient interactions, especially with iron and certain antibiotics or thyroid hormones, advising separation of doses.
Alternative Therapies
- Individual vitamin and mineral supplements (e.g., separate folic acid, iron, vitamin D, DHA supplements) if a combination product is not tolerated or specific deficiencies require higher doses.
Cost & Coverage
Average Cost:
$30 - $60 per 30 strips
Generic Available:
Yes
Insurance Coverage:
Often covered by insurance with a prescription, but may also be purchased OTC. Coverage varies by plan.
General Drug Facts
If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it occurred.