Tropicamide 1% Ophth Soln 3ml

Tropicamide is an anticholinergic agent that blocks the responses of the sphincter muscle of the iris and the ciliary body muscle to cholinergic stimulation, producing mydriasis (pupil dilation) and cycloplegia (paralysis of accommodation). It acts by competitively blocking muscarinic receptors (M1, M2, M3, M4, M5) in the eye.

Serious Side Effects: Seek Medical Help Immediately
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek medical attention right away:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Eye pain
Fast heartbeat
Mood changes
Changes in behavior
Pale skin
Muscle stiffness

Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or do not go away, contact your doctor or seek medical help:

Stinging
Eye irritation
Blurred vision
Dry mouth
Headache
* Upset stomach or vomiting

Reporting Side Effects
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor for medical advice. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This information will help your doctor and pharmacist assess potential interactions between this medication and other substances.
* Any existing health problems, as this medication may interact with certain conditions.

To ensure your safety, it is crucial to verify that it is safe to take this medication with all your current medications and health conditions. Do not initiate, discontinue, or modify the dosage of any medication without first consulting your doctor.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.

While using this drug, be cautious when performing tasks that require clear vision, as your pupils may be dilated. Avoid driving and other activities that demand sharp eyesight until your vision returns to normal.

You may experience sensitivity to bright lights for a period after using this medication. To minimize discomfort, wear sunglasses as directed by your doctor.

When administering this drug to children, exercise caution, as they may be at a higher risk of experiencing certain side effects.

If you are pregnant, planning to become pregnant, or are breastfeeding, consult your doctor to discuss the potential benefits and risks of this medication to both you and your baby.

• Other ophthalmic anticholinergics (e.g., atropine, scopolamine): May lead to additive systemic anticholinergic effects.
• Oral anticholinergics (e.g., tricyclic antidepressants, antihistamines, phenothiazines, quinidine, disopyramide): May increase risk of systemic anticholinergic side effects if significant systemic absorption occurs.

• Blurred vision (expected)
• Photophobia (expected)
• Eye irritation/stinging (common)
• Dry mouth
• Flushing of skin
• Fever
• Tachycardia
• Urinary retention
• Confusion or disorientation (rare, especially in children)
• Severe eye pain (seek immediate medical attention)

Use with caution during pregnancy. While systemic absorption is minimal, animal reproduction studies have not been conducted. Use only if the potential benefit justifies the potential risk to the fetus.

Use with caution. It is not known whether tropicamide is excreted in human milk. Due to minimal systemic absorption, risk to the infant is likely low. Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for tropicamide and any potential adverse effects on the breastfed infant from tropicamide or from the underlying maternal condition.

Use with extreme caution, especially in infants and young children, due to increased susceptibility to systemic anticholinergic toxicity (e.g., CNS disturbances, cardiorespiratory collapse, fever, abdominal distention). Use the lowest effective concentration and number of drops. Apply pressure to the lacrimal sac for 2-3 minutes after instillation to minimize systemic absorption.

Use with caution in elderly patients, especially those with a predisposition to angle-closure glaucoma, as mydriatics can precipitate an acute attack. Monitor intraocular pressure. May be more sensitive to systemic anticholinergic effects, though rare with ophthalmic use.

• Always check for a history of narrow-angle glaucoma or shallow anterior chamber before administering tropicamide, as it can precipitate an acute angle-closure attack.
• Educate patients about expected blurred vision and photophobia, and advise them not to drive or operate machinery until vision returns to normal.
• Provide disposable sunglasses to patients after dilation.
• In pediatric patients, apply nasolacrimal occlusion (gentle pressure on the inner corner of the eye for 2-3 minutes) after instillation to minimize systemic absorption and reduce the risk of adverse effects.
• Tropicamide has a faster onset and shorter duration of action compared to atropine, making it preferred for routine ophthalmic examinations.

• Cyclopentolate (stronger cycloplegic, longer duration)
• Atropine (strongest cycloplegic, longest duration, used therapeutically)
• Phenylephrine (pure mydriatic, no cycloplegic effect)
• Homatropine (intermediate mydriatic/cycloplegic)

If your symptoms or health problems persist or worsen, it is essential to contact your doctor for further evaluation and guidance. To ensure safe and effective use of your medication, never share your prescription with others, and do not take medication prescribed to someone else.

Store all medications in a secure location, out of the reach of children and pets, to prevent accidental ingestion. Dispose of unused or expired medications properly. Unless instructed otherwise by a healthcare professional or pharmacist, do not flush medications down the toilet or drain. If you are unsure about the proper disposal method, consult your pharmacist, who can provide guidance on safe disposal practices and inform you about potential drug take-back programs in your area.

Some medications may come with an additional patient information leaflet; check with your pharmacist to see if this applies to your prescription. If you have any questions or concerns about your medication, do not hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider.

In the event of a suspected overdose, immediately contact your local poison control center or seek emergency medical attention. Be prepared to provide critical information, including the name of the medication, the amount taken, and the time it was taken, to ensure prompt and effective treatment.