Sod Fluoride/pot Nit Sen 1.1-5% Pst
This supplement is used to prevent cavities.It is used to help sensitive teeth.
Drug Class
Desensitizing agent; Anticaries agent
Pharmacologic Class
Potassium salt (desensitizing); Fluoride (anticaries)
Pregnancy Category
Not applicable for topical dental product; minimal systemic absorption
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
This toothpaste contains two active ingredients: Sodium Fluoride helps prevent cavities and strengthen tooth enamel, while Potassium Nitrate helps reduce tooth sensitivity to hot, cold, sweets, or touch. It's designed to provide relief from sensitive teeth and protect against tooth decay.
How to Use This Medicine
Taking Your Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. Replace your regular toothpaste with this medication, unless your doctor advises otherwise. Brush your teeth as directed, then spit out the medication. Do not swallow it. Rinse your mouth thoroughly and spit out the rinse water.
Storing and Disposing of Your Medication
Store this medication at room temperature, in a safe location that is out of the reach of children and pets. When you no longer need this medication or it has expired, dispose of it properly. Do not flush it down the toilet or pour it down the drain unless instructed to do so. If you have questions about disposing of your medication, consult your pharmacist. You may also want to check if there are any drug take-back programs in your area.
Missing a Dose
If you miss a dose, use it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not use two doses at the same time or take extra doses.
To use this medication correctly, follow your doctor's instructions and read all the information provided. Replace your regular toothpaste with this medication, unless your doctor advises otherwise. Brush your teeth as directed, then spit out the medication. Do not swallow it. Rinse your mouth thoroughly and spit out the rinse water.
Storing and Disposing of Your Medication
Store this medication at room temperature, in a safe location that is out of the reach of children and pets. When you no longer need this medication or it has expired, dispose of it properly. Do not flush it down the toilet or pour it down the drain unless instructed to do so. If you have questions about disposing of your medication, consult your pharmacist. You may also want to check if there are any drug take-back programs in your area.
Missing a Dose
If you miss a dose, use it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular schedule. Do not use two doses at the same time or take extra doses.
Lifestyle & Tips
- Brush teeth thoroughly at least twice a day, or as directed by your dentist.
- Use a soft-bristled toothbrush and brush gently to avoid further gum recession or enamel wear.
- Avoid rinsing excessively after brushing to allow the active ingredients to remain on the teeth.
- Limit consumption of acidic foods and drinks, which can worsen sensitivity and enamel erosion.
- Maintain regular dental check-ups and cleanings.
Available Forms & Alternatives
Available Strengths:
- Sod Fluoride 1.1 (.5mg)/ml Drp 50ml
- Sodium Fluoride 1.1mg (0.5mg)chew T
- Sodium Fluoride 1.0mg Chewable Tabs
- Sod Fluoride 0.55mg (0.25mg)chew T
- Sod Fluoride 5000 1.1% Pste/sprmint
- Sod Fluoride 5000 1.1% Paste/fruit
- Sod Fluor 5000 1.1% Pst (dry Mouth)
- Sod Fluoride 5000 Ppm Ena Pro Pst
- Sod Fluoride 0.2% Mint Solution
- Sod Fluoride/pot Nit Sen 1.1-5% Pst
Dosing & Administration
Adult Dosing
Standard Dose:
Apply at least a 1-inch strip of product onto a soft bristled toothbrush. Brush teeth thoroughly for at least 1 minute, preferably after each meal or at least twice a day (morning and evening), or as directed by a dentist or physician.
Pediatric Dosing
Neonatal:
Not established
Infant:
Not established (typically not recommended for children under 2 years without dentist's advice)
Child:
Children 2-6 years: Use a pea-sized amount. Supervise brushing to minimize swallowing. Children 6-12 years: Use a pea-sized amount. Supervise brushing to minimize swallowing.
Adolescent:
Adolescents 12 years and older: Apply at least a 1-inch strip of product onto a soft bristled toothbrush. Brush teeth thoroughly for at least 1 minute, preferably after each meal or at least twice a day (morning and evening), or as directed by a dentist or physician.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Dialysis:
No specific considerations for topical use
Hepatic Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Pharmacology
Mechanism of Action
Sodium Fluoride: Works by promoting remineralization of demineralized enamel, inhibiting demineralization, and interfering with bacterial metabolism to reduce acid production. It incorporates into the tooth structure to form fluorapatite, making enamel more resistant to acid attacks. Potassium Nitrate: Acts as a desensitizing agent by depolarizing the nerve fibers within the dentinal tubules, thereby reducing their ability to transmit pain signals to the pulp.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption from topical application; most is spit out.
Tmax:
Not clinically relevant for topical use.
FoodEffect:
Not applicable for topical dental product.
Distribution:
Vd:
Not clinically relevant for topical use. If absorbed, fluoride distributes to calcified tissues.
ProteinBinding:
Not clinically relevant for topical use.
CnssPenetration:
Limited (not clinically relevant for topical use).
Elimination:
HalfLife:
Not clinically relevant for topical use. If absorbed, fluoride is primarily renally excreted (half-life varies based on age and renal function).
Clearance:
Not clinically relevant for topical use.
ExcretionRoute:
Not clinically relevant for topical use. If absorbed, primarily renal.
Unchanged:
Not clinically relevant for topical use.
Pharmacodynamics
OnsetOfAction:
Desensitizing effect of potassium nitrate may be noticed within 2 weeks of regular use, with optimal relief after 2-4 weeks. Anticaries effect of fluoride is continuous with regular use.
PeakEffect:
Optimal desensitization after 2-4 weeks of continuous use.
DurationOfAction:
Effects persist with continued regular use.
Confidence:
Medium
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Attention Immediately
If you experience any of the following symptoms, call your doctor or seek medical help right away, as they may be signs of a severe and potentially life-threatening side effect:
- Signs of an allergic reaction, such as:
- Rash
- Hives
- Itching
- Red, swollen, blistered, or peeling skin, with or without fever
- Wheezing
- Tightness in the chest or throat
- Trouble breathing, swallowing, or talking
- Unusual hoarseness
- Swelling of the mouth, face, lips, tongue, or throat
- Severe upset stomach or vomiting
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
If you experience any of the following symptoms, call your doctor or seek medical help right away, as they may be signs of a severe and potentially life-threatening side effect:
- Signs of an allergic reaction, such as:
- Rash
- Hives
- Itching
- Red, swollen, blistered, or peeling skin, with or without fever
- Wheezing
- Tightness in the chest or throat
- Trouble breathing, swallowing, or talking
- Unusual hoarseness
- Swelling of the mouth, face, lips, tongue, or throat
- Severe upset stomach or vomiting
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you have side effects that bother you or do not go away, contact your doctor for advice.
Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Sensitivity persists or worsens after 4 weeks of use
- Gum irritation, redness, or swelling
- Allergic reaction (e.g., rash, itching, swelling of face/tongue/throat, severe dizziness, trouble breathing)
- Nausea, vomiting, or stomach upset (especially if swallowed in large amounts)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain health conditions, including:
+ Bone problems
+ Joint problems
+ Kidney problems
+ Ulcers
The level of fluoride in your drinking water, particularly if it is greater than or equal to 0.6 parts per million.
Additionally, to ensure safe treatment, provide your doctor and pharmacist with a comprehensive list of:
All prescription and over-the-counter (OTC) medications you are taking
Any natural products or vitamins you are using
Your overall health problems
This information will help your doctor determine if it is safe for you to take this medication with your other drugs and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor to confirm it is safe to do so.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain health conditions, including:
+ Bone problems
+ Joint problems
+ Kidney problems
+ Ulcers
The level of fluoride in your drinking water, particularly if it is greater than or equal to 0.6 parts per million.
Additionally, to ensure safe treatment, provide your doctor and pharmacist with a comprehensive list of:
All prescription and over-the-counter (OTC) medications you are taking
Any natural products or vitamins you are using
Your overall health problems
This information will help your doctor determine if it is safe for you to take this medication with your other drugs and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor to confirm it is safe to do so.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you notice any tooth staining or spotting, be sure to notify your dentist. Regular dental care is crucial, so schedule frequent dental check-ups to maintain good oral health.
In the event of accidental ingestion of a large amount of this medication, seek immediate medical attention by calling a doctor or poison control center right away, as it can be harmful. When administering this medication to children, note that different brands may have varying dosage recommendations. Therefore, consult with your doctor before giving this medication to a child to ensure the correct dosage.
If you are pregnant, planning to become pregnant, or are breast-feeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision.
In the event of accidental ingestion of a large amount of this medication, seek immediate medical attention by calling a doctor or poison control center right away, as it can be harmful. When administering this medication to children, note that different brands may have varying dosage recommendations. Therefore, consult with your doctor before giving this medication to a child to ensure the correct dosage.
If you are pregnant, planning to become pregnant, or are breast-feeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision.
Overdose Information
Overdose Symptoms:
- Acute ingestion of large amounts (especially by children) can cause nausea, vomiting, abdominal pain, diarrhea, and salivation.
- Chronic ingestion of excessive fluoride during tooth development can lead to dental fluorosis (white or brown spots on teeth).
What to Do:
If a large amount is swallowed, contact a Poison Control Center immediately (e.g., 1-800-222-1222) or seek emergency medical attention. Induce vomiting only if directed by medical personnel. Administer milk or calcium-containing liquids to bind fluoride.
Drug Interactions
Monitoring
Baseline Monitoring
Dental examination
Rationale: To identify underlying causes of sensitivity and assess overall oral health.
Timing: Prior to initiating use, as recommended by a dentist.
Routine Monitoring
Oral hygiene practices
Frequency: Daily
Target: Effective plaque removal, proper brushing technique
Action Threshold: Ineffective brushing, continued sensitivity, or gum irritation should prompt dental consultation.
Symptom Monitoring
- Persistent or worsening tooth sensitivity
- Gum irritation or inflammation
- Allergic reactions (e.g., rash, itching, swelling)
- Oral discomfort
Special Patient Groups
Pregnancy
Generally considered safe for topical use during pregnancy due to minimal systemic absorption. Consult with a healthcare provider or dentist if concerns arise.
Trimester-Specific Risks:
First Trimester:
Low risk
Second Trimester:
Low risk
Third Trimester:
Low risk
Lactation
Generally considered safe for use during lactation due to minimal systemic absorption and unlikely transfer into breast milk in clinically significant amounts. Consult with a healthcare provider or dentist if concerns arise.
Infant Risk:
Low risk
Pediatric Use
Use in children under 12 years should be supervised to ensure proper brushing technique and minimize swallowing. For children under 2 years, consult a dentist. Age-appropriate amounts (smear for <2, pea-sized for 2-6) are crucial to prevent fluorosis.
Geriatric Use
No specific dosage adjustments or precautions are generally needed for geriatric patients. Standard use as per adult recommendations.
Clinical Information
Clinical Pearls
- Advise patients that consistent, regular use (at least twice daily) is key for both sensitivity relief and cavity protection.
- Emphasize that sensitivity relief from potassium nitrate is gradual and may take 2-4 weeks to become fully effective.
- Instruct patients not to rinse excessively after brushing to maximize the contact time of fluoride and potassium nitrate with the tooth surface.
- Recommend using a soft-bristled toothbrush to avoid further abrasion of sensitive areas.
- If sensitivity persists or worsens after 4 weeks of use, advise the patient to consult their dentist to rule out other underlying dental issues (e.g., cavities, cracked teeth, gum disease).
Alternative Therapies
- Fluoride varnishes or gels (professional application for caries prevention).
- Dental bonding or sealants for exposed dentin (for sensitivity).
- Gum grafting procedures (for severe gum recession causing sensitivity).
- Dietary modifications to reduce acidic food/drink intake.
- Other desensitizing agents like strontium chloride or arginine-calcium carbonate technology.
Cost & Coverage
Average Cost:
Varies widely ($5 - $15) per tube (e.g., 4 oz)
Generic Available:
Yes
Insurance Coverage:
Over-the-counter (OTC), generally not covered by medical insurance. May be eligible for FSA/HSA reimbursement.
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the medication taken, the amount, and the time it occurred.