Nutraplus 10% Lotion 473ml

Manufacturer BAUSCH HEALTH Active Ingredient Urea Lotion(yoor EE a) Pronunciation yoor EE a
It is used to treat some skin problems. It is used to treat some nail problems.
đŸˇī¸
Drug Class
Keratolytic; Emollient; Humectant
đŸ§Ŧ
Pharmacologic Class
Keratolytic; Humectant
🤰
Pregnancy Category
Category B
✅
FDA Approved
Jan 1970
âš–ī¸
DEA Schedule
Not Controlled

Overview

â„šī¸

What is this medicine?

Urea lotion is a skin moisturizer and softener. It helps to hydrate dry, rough, or scaly skin by drawing moisture into the skin and helping to loosen dead skin cells, making the skin smoother and softer.
📋

How to Use This Medicine

Using Your Medication Correctly

To use this medication safely and effectively, follow your doctor's instructions and read all the information provided. This medication is for topical use only, meaning it should be applied directly to the affected area of your skin. Avoid getting it in your mouth, nose, or eyes, as it may cause burning.

Before applying the medication, wash your hands thoroughly. If the affected area is on your hand, you do not need to wash that hand after application. Clean the affected area before use and make sure it is completely dry. Then, apply a thin layer of the medication to the affected skin and gently rub it in.

Apply the medication only to the affected area. If necessary, you can cover the treated area with a bandage or dressing. Remember to shake the container well before each use.

Storing and Disposing of Your Medication

To maintain the quality and safety of your medication, store it at room temperature, avoiding freezing temperatures. Protect the medication from heat sources and keep the lid tightly closed when not in use.

What to Do If You Miss a Dose

If you forget to apply a dose, put it on as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply two doses at the same time or use extra doses to make up for a missed one.
💡

Lifestyle & Tips

  • Apply to clean, dry skin.
  • Wash hands before and after application.
  • Avoid contact with eyes, nose, mouth, and other mucous membranes.
  • Do not apply to broken, inflamed, or irritated skin unless directed by a healthcare professional.
  • For external use only.
  • Regular, consistent use is key for best results.
💊

Available Forms & Alternatives

Dosing & Administration

đŸ‘¨â€âš•ī¸

Adult Dosing

Standard Dose: Apply to affected skin areas 1 to 3 times daily, or as directed by a physician.

Condition-Specific Dosing:

dry, rough skin: Apply liberally to affected areas.
hyperkeratotic conditions: May require more frequent application or higher concentrations.
đŸ‘ļ

Pediatric Dosing

Neonatal: Not established (use with caution, consult pediatrician)
Infant: Not established (use with caution, consult pediatrician)
Child: Apply to affected skin areas 1 to 3 times daily, or as directed by a physician. Use with caution on large areas or broken skin.
Adolescent: Apply to affected skin areas 1 to 3 times daily, or as directed by a physician.
âš•ī¸

Dose Adjustments

Renal Impairment:

Mild: No adjustment needed (topical use)
Moderate: No adjustment needed (topical use)
Severe: No adjustment needed (topical use)
Dialysis: No adjustment needed (topical use)

Hepatic Impairment:

Mild: No adjustment needed (topical use)
Moderate: No adjustment needed (topical use)
Severe: No adjustment needed (topical use)

Pharmacology

đŸ”Ŧ

Mechanism of Action

Urea is a humectant, attracting and holding moisture in the stratum corneum. It also has keratolytic properties, helping to dissolve the intercellular matrix of the stratum corneum, promoting desquamation and softening of hyperkeratotic areas. At lower concentrations (e.g., 10%), it primarily acts as a humectant and emollient.
📊

Pharmacokinetics

Absorption:

Bioavailability: Minimal systemic absorption from intact skin
Tmax: Not applicable (topical action)
FoodEffect: Not applicable

Distribution:

Vd: Not applicable (minimal systemic absorption)
ProteinBinding: Not applicable (minimal systemic absorption)
CnssPenetration: No (minimal systemic absorption)

Elimination:

HalfLife: Not applicable (minimal systemic absorption)
Clearance: Not applicable (minimal systemic absorption)
ExcretionRoute: Not applicable (minimal systemic absorption; if absorbed, primarily renal)
Unchanged: Not applicable (minimal systemic absorption)
âąī¸

Pharmacodynamics

OnsetOfAction: Within days for emollient effect; longer for significant keratolytic effect (if applicable at higher concentrations)
PeakEffect: Varies with condition and concentration
DurationOfAction: Maintained with regular application

Safety & Warnings

âš ī¸

Side Effects

Urgent Side Effects: Seek Medical Help Right Away
If you experience any of the following symptoms, call your doctor immediately or seek emergency medical attention, as they may be signs of a severe and potentially life-threatening reaction:
- Signs of an allergic reaction, such as rash, hives, itching, red, swollen, blistered, or peeling skin (with or without fever), wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.

Other Possible Side Effects
Like all medications, this drug can cause side effects, although not everyone will experience them. Many people have either no side effects or only mild ones. If you encounter any of the following side effects or any other unusual effects that concern you or do not go away, contact your doctor for advice:
- Burning or stinging
- Itching
- Irritation at the site where the drug was applied

Reporting Side Effects
This list does not include all possible side effects. If you have questions or concerns about side effects, consult your doctor. For medical advice about side effects, you can also contact your doctor. Additionally, you can report side effects to the FDA at 1-800-332-1088 or through their website at https://www.fda.gov/medwatch.
🚨

Seek Immediate Medical Attention If You Experience:

  • Severe burning, stinging, or irritation after application.
  • Development of a rash or allergic reaction (e.g., hives, swelling).
  • Signs of infection (e.g., pus, fever) if applied to broken skin.
📋

Before Using This Medicine

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
Potential interactions with other medications or health conditions. This medication may affect or be affected by other drugs or health problems.

To ensure safe use, provide your doctor and pharmacist with a comprehensive list of:
All prescription and over-the-counter (OTC) medications you are taking
Any natural products or vitamins you are using
Existing health problems

Before making any changes to your medication regimen, consult with your doctor to confirm that it is safe to:
Start taking this medication
Stop taking this medication
Change the dosage of this medication or any other medication you are taking
âš ī¸

Precautions & Cautions

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Adhere to the prescribed duration of use, as directed by your doctor, and do not exceed it.

In case of accidental ingestion, this medication can be harmful. If swallowed, immediately contact a doctor or a poison control center for assistance.

To ensure safe use, avoid applying this medication to irritated skin, open wounds, or infected skin areas. Using this medication too frequently can exacerbate your skin condition.

Before using any other medications or products on your skin, including soaps, consult with your doctor to discuss potential interactions. If you are pregnant, planning to become pregnant, or are breast-feeding, inform your doctor to weigh the benefits and risks of using this medication to you and your baby.
🆘

Overdose Information

Overdose Symptoms:

  • Topical overdose is unlikely to cause systemic toxicity.
  • Excessive application may lead to increased local irritation (burning, stinging, redness).

What to Do:

If excessive local irritation occurs, wash the area with water. If ingested, seek immediate medical attention or call a poison control center (1-800-222-1222).

Drug Interactions

đŸŸĸ

Minor Interactions

  • Other topical medications (may increase absorption of other topicals if applied concurrently on the same area, especially on broken skin)

Monitoring

📊

Routine Monitoring

Skin condition (hydration, texture, irritation)

Frequency: Daily, with each application

Target: Improved hydration, reduced roughness, absence of irritation

Action Threshold: Increased redness, burning, stinging, itching, or worsening of skin condition

đŸ‘ī¸

Symptom Monitoring

  • Skin irritation (redness, burning, stinging, itching)
  • Allergic reactions (rash, swelling)
  • Worsening of underlying skin condition

Special Patient Groups

🤰

Pregnancy

Generally considered safe for topical use during pregnancy. Minimal systemic absorption is expected.

Trimester-Specific Risks:

First Trimester: Low risk
Second Trimester: Low risk
Third Trimester: Low risk
🤱

Lactation

Considered safe for use during lactation. Minimal systemic absorption means negligible excretion into breast milk. Avoid applying to areas where the infant may ingest it (e.g., nipples).

Infant Risk: Low risk
đŸ‘ļ

Pediatric Use

Generally safe for children, but use with caution on large body surface areas or broken skin, especially in infants and very young children, due to potentially increased absorption. Consult a pediatrician for use in infants.

👴

Geriatric Use

Generally safe for geriatric patients. No specific dose adjustments are typically needed. Monitor for skin sensitivity or fragility.

Clinical Information

💎

Clinical Pearls

  • Urea is a versatile ingredient, acting as a humectant at lower concentrations (e.g., 10%) and a keratolytic at higher concentrations (e.g., 20-40%).
  • Patients may experience mild stinging or burning, especially on sensitive or broken skin. This usually subsides with continued use.
  • Advise patients to apply to damp skin after bathing for optimal hydration.
  • Can be used for various dry skin conditions, including xerosis, ichthyosis, psoriasis, and eczema.
  • Avoid applying to open wounds or severely inflamed skin unless specifically directed by a healthcare provider.
🔄

Alternative Therapies

  • Lactic acid lotions (e.g., AmLactin)
  • Alpha hydroxy acid (AHA) lotions
  • Salicylic acid topical preparations
  • Emollients (e.g., petrolatum, mineral oil, dimethicone)
  • Humectants (e.g., glycerin, hyaluronic acid)
  • Topical corticosteroids (for inflammatory conditions)
💰

Cost & Coverage

Average Cost: $15 - $30 per 473ml lotion
Generic Available: Yes
Insurance Coverage: Often OTC, may not be covered by insurance unless prescribed by a physician for specific conditions.
📚

General Drug Facts

If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about this medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek medical attention. When seeking help, be prepared to provide details about the overdose, including the medication taken, the amount, and the time it occurred.