Nicotine TD 14mg/24h Patch 7s

Nicotine acts as an agonist at nicotinic acetylcholine receptors in the central and peripheral nervous systems. In smoking cessation, it replaces the nicotine from tobacco, reducing withdrawal symptoms and cravings associated with nicotine dependence. The transdermal patch delivers a continuous, controlled dose of nicotine to maintain steady plasma levels.

Urgent Side Effects: Seek Medical Attention Immediately

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical help right away:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of high blood pressure, including:
+ Severe headache
+ Dizziness
+ Passing out
+ Changes in eyesight
Mood changes
Confusion
Chest pain or pressure
Fast or abnormal heartbeat
Abnormal sensations, such as burning, numbness, or tingling
Dizziness, tiredness, or weakness
Diarrhea
Upset stomach or vomiting
Drooling
Shakiness
Cold sweats
Blurred vision
Changes in hearing

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or do not go away, contact your doctor:

Sleep disturbances
Bad dreams
Nervousness or excitability
Headache
Joint pain
Back pain
Irritation at the site of application

This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
Certain health conditions, including:
+ Chest pain or pressure
+ An irregular heartbeat
+ A recent heart attack
If you currently use tobacco products, such as smoking or chewing tobacco, or use other nicotine-containing products while taking this medication.
If you are under 18 years of age. This medication is not recommended for children under 18 years old without first consulting a doctor.

This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health problems with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions. Never start, stop, or change the dose of any medication without first consulting your doctor.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. To increase your chances of quitting smoking, consider seeking counseling to help you overcome nicotine addiction.

To minimize the risk of adverse effects, do not exceed the recommended dosage. Taking more than the prescribed amount can lead to unsafe side effects. If you are using another medication to help you quit smoking, be sure to inform your doctor.

When attempting to quit smoking, even with the assistance of medications like this one, you may experience symptoms of nicotine withdrawal. These symptoms can vary, so it is crucial to report any adverse effects to your doctor.

Until you are familiar with how this medication affects you, avoid driving and engaging in other activities that require your full attention. Additionally, be aware that quitting smoking can alter the effectiveness of other medications you are taking. Therefore, consult your doctor to discuss any potential interactions.

If you have not been able to quit smoking after using this medication for the recommended duration, inform your doctor. The patch contains metal, so it is essential to remove it before undergoing an MRI.

Some users may experience strange dreams or sleep disturbances. If this occurs, consider removing the patch at bedtime. It is vital to handle the patch with care, as chewing or swallowing it can cause harm. If the patch is accidentally ingested, immediately contact a doctor or poison control center.

This medication can be hazardous or even fatal if ingested by children or pets. If a child uses the patch or if it is swallowed by a child or pet, promptly contact a doctor or poison control center.

If you are 65 or older, use this medication with caution, as you may be more susceptible to side effects. Additionally, this medication may pose a risk to the unborn baby if taken during pregnancy. If you become pregnant or are pregnant while using this medication, notify your doctor immediately.

If you are breastfeeding, consult your doctor to discuss any potential risks to your baby.

• Not applicable (no absolute contraindications based on drug-drug interactions)

• Not applicable

• Adenosine (nicotine may increase heart rate and blood pressure, potentially reducing adenosine's effectiveness)
• Beta-blockers (smoking cessation can increase beta-blocker levels due to reduced CYP1A2 induction; monitor blood pressure and heart rate)
• Insulin (smoking cessation can increase insulin absorption and sensitivity; monitor blood glucose and adjust insulin dose)
• Theophylline (smoking cessation can increase theophylline levels due to reduced CYP1A2 induction; monitor theophylline levels)
• Caffeine (smoking cessation can increase caffeine levels due to reduced CYP1A2 induction; monitor for increased caffeine side effects)
• Adrenergic agonists (e.g., phenylephrine, isoproterenol) (nicotine may potentiate cardiovascular effects)
• Adrenergic antagonists (e.g., prazosin, labetalol) (nicotine may reduce their hypotensive effects)

• Not applicable

• Nausea
• Vomiting
• Dizziness
• Headache
• Palpitations
• Sleep disturbances (insomnia, vivid dreams)
• Skin irritation (redness, itching, burning at application site)
• Muscle aches
• Tremor
• Sweating
• Confusion
• Weakness
• Seizures (rare, severe overdose)

Category D. Nicotine crosses the placenta and can cause fetal harm, including reduced fetal breathing movements, increased fetal heart rate, and potential for adverse long-term neurodevelopmental effects. However, the risks of continued smoking during pregnancy are significantly higher than the risks of NRT. If a pregnant woman cannot quit smoking through non-pharmacological methods, NRT may be considered under strict medical supervision, with the lowest effective dose and shortest duration. Intermittent NRT (e.g., gum, lozenge) may be preferred over patches to allow for nicotine-free periods.

Nicotine is excreted into breast milk and can be harmful to the infant. However, the risks of infant exposure to nicotine from NRT are significantly lower than the risks from maternal smoking. If NRT is used during lactation, the lowest effective dose should be used, and the patch should be removed before breastfeeding (e.g., remove 24-hour patch at night if breastfeeding in the morning) to minimize infant exposure. Intermittent NRT (gum, lozenge) may be preferred to allow for nicotine-free periods.

Not recommended for individuals under 18 years of age for smoking cessation without medical supervision. Efficacy and safety are not well-established in this population. Non-pharmacological interventions are preferred.

Use with caution. Elderly patients may be more sensitive to the effects of nicotine, particularly cardiovascular effects. Consider starting with a lower dose (e.g., 14 mg/24h or 7 mg/24h) and titrating slowly based on tolerance and efficacy. Monitor closely for adverse effects.

• Emphasize complete cessation of smoking when starting NRT to avoid nicotine overdose.
• Advise patients to rotate patch application sites daily to minimize skin irritation. Hydrocortisone cream can be used for mild irritation.
• The 24-hour patch can cause sleep disturbances (insomnia, vivid dreams) in some patients. If this occurs, advise removing the patch at bedtime (after 16 hours of wear) and applying a new one in the morning, though this may reduce overall nicotine delivery.
• NRT is most effective when combined with behavioral counseling and support programs.
• Patients should be advised that the patch is not a 'magic bullet' but a tool to help manage withdrawal symptoms while they work on breaking the behavioral aspects of smoking.
• Disposal of used patches is critical; they still contain enough nicotine to be harmful to children or pets. Fold sticky sides together and dispose of safely.

• Other Nicotine Replacement Therapies (NRTs): Nicotine gum, nicotine lozenge, nicotine inhaler, nicotine nasal spray.
• Pharmacological non-nicotine therapies: Bupropion SR (Zyban, Wellbutrin SR), Varenicline (Chantix).
• Non-pharmacological therapies: Behavioral counseling, cognitive behavioral therapy (CBT), support groups, quitlines, acupuncture, hypnotherapy (efficacy varies).

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it is a good idea to consult with your pharmacist. If you have any questions or concerns about this medication, do not hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide detailed information about the overdose, including the medication taken, the amount, and the time it occurred.