Medihoney Wound Gel 44ml
It is used to treat or prevent certain skin problems.It may be given to you for other reasons. Talk with the doctor.
Drug Class
Wound Care Agent
Pharmacologic Class
Osmotic Debriding Agent, Antimicrobial (Topical)
Pregnancy Category
Not applicable (Topical product, generally considered safe)
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Medihoney Wound Gel is a special type of honey in a gel form used to help wounds heal. It works by keeping the wound moist, cleaning it, and helping to fight off germs. It can be used for many types of wounds, including cuts, scrapes, burns, and ulcers.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication only as directed.
Application Instructions
Do not take this medication by mouth. It is for skin use only.
Avoid getting the medication in your mouth, nose, ears, or eyes, as it may cause burning.
If your medication requires shaking before use, make sure you understand the instructions before applying it.
Wash your hands before and after applying the medication, unless your hand is the treated area. In this case, do not wash your hand after application.
Clean the affected area before applying the medication and dry it thoroughly.
Apply the medication to the affected area as instructed by your doctor. You may need to cover the treated area with a bandage or dressing; consult with your doctor for guidance.
Storage and Disposal
Store the medication at room temperature and do not freeze it.
Check the storage information provided with the medication to determine how long you can store it before disposing of it. If you have questions, consult with your pharmacist.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not use it more frequently than instructed by your doctor.
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication only as directed.
Application Instructions
Do not take this medication by mouth. It is for skin use only.
Avoid getting the medication in your mouth, nose, ears, or eyes, as it may cause burning.
If your medication requires shaking before use, make sure you understand the instructions before applying it.
Wash your hands before and after applying the medication, unless your hand is the treated area. In this case, do not wash your hand after application.
Clean the affected area before applying the medication and dry it thoroughly.
Apply the medication to the affected area as instructed by your doctor. You may need to cover the treated area with a bandage or dressing; consult with your doctor for guidance.
Storage and Disposal
Store the medication at room temperature and do not freeze it.
Check the storage information provided with the medication to determine how long you can store it before disposing of it. If you have questions, consult with your pharmacist.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not use it more frequently than instructed by your doctor.
Lifestyle & Tips
- Follow your healthcare provider's instructions for wound care.
- Maintain good hand hygiene before and after dressing changes.
- Keep the wound clean and protected as advised.
- Report any signs of infection or worsening wound condition to your doctor or nurse.
Available Forms & Alternatives
Available Strengths:
Dosing & Administration
Adult Dosing
Standard Dose:
Apply directly to the wound bed or to a suitable dressing, ensuring the wound surface is covered. Reapply at each dressing change.
Condition-Specific Dosing:
frequency:
Typically changed daily or every 2-3 days, depending on wound exudate levels and clinical assessment.
Pediatric Dosing
Neonatal:
Apply as directed by healthcare professional for appropriate wound types.
Infant:
Apply as directed by healthcare professional for appropriate wound types.
Child:
Apply as directed by healthcare professional for appropriate wound types.
Adolescent:
Apply as directed by healthcare professional for appropriate wound types.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed (topical product, minimal systemic absorption).
Moderate:
No adjustment needed (topical product, minimal systemic absorption).
Severe:
No adjustment needed (topical product, minimal systemic absorption).
Dialysis:
No specific considerations (topical product, minimal systemic absorption).
Hepatic Impairment:
Mild:
No adjustment needed (topical product, minimal systemic absorption).
Moderate:
No adjustment needed (topical product, minimal systemic absorption).
Severe:
No adjustment needed (topical product, minimal systemic absorption).
Pharmacology
Mechanism of Action
Medihoney Wound Gel contains 100% Leptospermum scoparium (Manuka) honey. Its mechanism of action in wound healing is multi-faceted: 1. **Osmotic Effect:** The high sugar content creates a hyperosmolar environment, drawing fluid from the wound bed (exudate) and surrounding tissues. This reduces edema, promotes autolytic debridement, and creates a moist wound healing environment. 2. **Antimicrobial Activity:** The high sugar content inhibits bacterial growth by dehydrating bacteria. Additionally, honey has a low pH (acidic), which is unfavorable for many pathogenic bacteria. Some honeys, including Manuka honey, also produce low levels of hydrogen peroxide when diluted by wound exudate, contributing to antimicrobial action. 3. **Anti-inflammatory Properties:** Honey has been shown to reduce inflammation and pain in wounds. 4. **Debridement:** The osmotic action helps to lift and remove slough and necrotic tissue. 5. **Odor Reduction:** By reducing bacterial load and absorbing exudate, honey can help reduce wound odor. The gel formulation provides a viscous consistency for easy application and adherence to the wound bed.
Pharmacokinetics
Absorption:
Bioavailability:
Not applicable (minimal to no systemic absorption from topical application)
Tmax:
Not applicable
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable
ProteinBinding:
Not applicable
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable
Clearance:
Not applicable
ExcretionRoute:
Not applicable
Unchanged:
Not applicable
Pharmacodynamics
OnsetOfAction:
Local effects (e.g., osmotic action, debridement) begin upon application. Antimicrobial and anti-inflammatory effects are continuous with presence on the wound.
PeakEffect:
Continuous local effect throughout wear time.
DurationOfAction:
Up to 72 hours, depending on exudate levels and dressing change frequency.
Confidence:
High
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Right Away
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. Immediately contact your doctor or seek medical attention if you experience any of the following symptoms:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of skin infection, including:
+ Oozing
+ Heat
+ Swelling
+ Redness
+ Pain
Abnormal bleeding from the affected area
Fever
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people do not experience any side effects or only have mild ones, it is essential to discuss any concerns with your doctor. Contact your doctor or seek medical help if you experience any of the following side effects or if they persist or bother you:
* Skin irritation
Note: This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. For medical advice about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. Immediately contact your doctor or seek medical attention if you experience any of the following symptoms:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of skin infection, including:
+ Oozing
+ Heat
+ Swelling
+ Redness
+ Pain
Abnormal bleeding from the affected area
Fever
Other Possible Side Effects
Like all medications, this drug can cause side effects. Although many people do not experience any side effects or only have mild ones, it is essential to discuss any concerns with your doctor. Contact your doctor or seek medical help if you experience any of the following side effects or if they persist or bother you:
* Skin irritation
Note: This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. For medical advice about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Increased pain at the wound site
- Redness, swelling, or warmth spreading from the wound
- Pus or foul-smelling discharge from the wound
- Fever or chills
- Rash or itching around the wound (may indicate an allergic reaction)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction and its symptoms.
If you have a skin rash caused by an allergic reaction to a food or medication.
* If you have a bleeding wound.
This list is not exhaustive, and it is crucial to discuss all your medications (including prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions.
Remember, do not start, stop, or change the dose of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction and its symptoms.
If you have a skin rash caused by an allergic reaction to a food or medication.
* If you have a bleeding wound.
This list is not exhaustive, and it is crucial to discuss all your medications (including prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions.
Remember, do not start, stop, or change the dose of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. Before using sunscreen with this drug, consult with your doctor to determine the best approach. Additionally, discuss with your doctor the use of other medications or products on your skin, including soaps, to ensure safe and effective treatment.
Certain brands of this medication may not be suitable for application on open sores, broken skin, or severe burns. Be sure to check with your doctor or pharmacist for specific guidance on using this medication.
Some products containing this drug may include metal components. If you have an upcoming procedure, such as an MRI, cardioversion, radiation, or other medical procedure, inform your doctor about this medication. You may need to remove the product before the procedure to ensure your safety.
In the event that this medication is swallowed, it can cause harm. If ingestion occurs, immediately contact a doctor or poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breast-feeding, notify your doctor. You will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision about treatment.
Certain brands of this medication may not be suitable for application on open sores, broken skin, or severe burns. Be sure to check with your doctor or pharmacist for specific guidance on using this medication.
Some products containing this drug may include metal components. If you have an upcoming procedure, such as an MRI, cardioversion, radiation, or other medical procedure, inform your doctor about this medication. You may need to remove the product before the procedure to ensure your safety.
In the event that this medication is swallowed, it can cause harm. If ingestion occurs, immediately contact a doctor or poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breast-feeding, notify your doctor. You will need to discuss the potential benefits and risks of this medication to both you and your baby to make an informed decision about treatment.
Overdose Information
Overdose Symptoms:
- Not applicable for topical application. Excessive application may lead to increased exudate or maceration of periwound skin, but no systemic overdose is expected.
What to Do:
Remove excess product, clean the wound and periwound skin, and apply a new dressing. If irritation occurs, discontinue use and consult a healthcare professional. For general poison control, call 1-800-222-1222.
Drug Interactions
Monitoring
Baseline Monitoring
Wound assessment (size, depth, exudate, tissue type, odor, pain)
Rationale: To establish baseline wound characteristics and guide treatment plan.
Timing: Prior to initial application.
Routine Monitoring
Wound assessment (changes in size, depth, exudate, tissue type, odor, pain)
Frequency: At each dressing change (daily to every 3 days).
Target: Improvement in wound characteristics (e.g., reduction in size, healthy granulation tissue, decreased exudate).
Action Threshold: Worsening wound condition, signs of infection (increased pain, redness, swelling, purulent exudate), or lack of improvement may require re-evaluation by a healthcare professional.
Periwound skin integrity
Frequency: At each dressing change.
Target: Intact, healthy skin.
Action Threshold: Maceration, irritation, or breakdown of periwound skin requires protective measures or adjustment of dressing.
Symptom Monitoring
- Increased wound pain (especially new or worsening)
- Increased redness or swelling around the wound
- Warmth around the wound
- Fever or chills (systemic signs of infection)
- Increased or purulent wound exudate
- Unusual or foul wound odor
- Rash or itching (signs of allergic reaction)
Special Patient Groups
Pregnancy
Generally considered safe for topical use during pregnancy as systemic absorption is minimal. Consult with a healthcare provider.
Trimester-Specific Risks:
First Trimester:
Minimal risk (topical product).
Second Trimester:
Minimal risk (topical product).
Third Trimester:
Minimal risk (topical product).
Lactation
Generally considered safe for use during lactation as systemic absorption is minimal and unlikely to pass into breast milk. Avoid application to the nipple area if breastfeeding.
Infant Risk:
Minimal risk.
Pediatric Use
Generally considered safe for use in pediatric patients for appropriate wound types. Dosage and frequency of dressing changes should be determined by a healthcare professional based on wound assessment.
Geriatric Use
Generally considered safe for use in geriatric patients. No specific dose adjustments are needed. Monitor for skin fragility and periwound integrity.
Clinical Information
Clinical Pearls
- Medihoney Wound Gel is effective for a wide range of wounds, including partial and full thickness wounds, ulcers (pressure, venous, diabetic), first and second-degree burns, surgical wounds, and traumatic wounds.
- Transient stinging or discomfort may occur upon initial application, especially in wounds with high exudate or inflammation. This usually subsides quickly.
- The osmotic action of honey may lead to an initial increase in wound exudate as it draws fluid from the wound. This is a normal part of the debridement process.
- Ensure the wound bed is adequately covered with the gel, but avoid excessive application that could lead to maceration of surrounding skin.
- Medihoney is contraindicated in patients with a known allergy to honey or bee venom.
- Not intended for use in third-degree burns or for internal use.
Alternative Therapies
- Silver-impregnated dressings (for antimicrobial action)
- Enzymatic debriding agents (e.g., Collagenase Santyl)
- Antimicrobial dressings (e.g., iodine, PHMB)
- Advanced wound care modalities (e.g., Negative Pressure Wound Therapy)
Cost & Coverage
Average Cost:
Varies, typically $20-$50 per 44ml tube
Insurance Coverage:
Often covered under medical benefits for wound care supplies, depending on insurance plan and medical necessity. May require prior authorization.
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek medical attention. When seeking help, be prepared to provide details about the medication, including the amount taken and the time it happened, to facilitate prompt and effective treatment.