Elocon 0.1% Lotion 30ml
It is used to treat skin rashes and other skin irritation.
Drug Class
Corticosteroid, Topical
Pharmacologic Class
Glucocorticoid receptor agonist
Pregnancy Category
Category C
FDA Approved
Mar 1987
DEA Schedule
Not Controlled
Overview
What is this medicine?
Elocon Lotion is a strong medicine that contains a corticosteroid. It is used on the skin to reduce redness, swelling, and itching caused by certain skin conditions like eczema or psoriasis. It works by calming down the body's immune response in the skin.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. Continue using the medication as directed, even if your symptoms improve.
Application Instructions
Apply this medication only to your skin, as directed by your doctor. Do not take it by mouth.
Avoid getting the medication in your mouth, nose, or eyes, as it may cause burning.
Unless instructed by your doctor, do not apply the medication to your face, underarms, or groin area.
Wash your hands before and after applying the medication. If the treated area is on your hand, do not wash your hand after application.
Clean the affected area before applying the medication and make sure it is dry.
Apply a thin layer of the medication to the affected skin and gently rub it in.
Do not cover the treated area with bandages or dressings unless instructed to do so by your doctor.
Storage and Disposal
Store the medication at room temperature.
Keep all medications in a safe place, out of the reach of children and pets.
Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposal, consult your pharmacist. You may also have access to drug take-back programs in your area.
Missed Dose
If you miss a dose, apply it as soon as you remember.
If it is close to the time for your next dose, skip the missed dose and resume your regular schedule.
* Do not apply two doses at the same time or use extra doses.
To use this medication correctly, follow your doctor's instructions and read all the information provided. Continue using the medication as directed, even if your symptoms improve.
Application Instructions
Apply this medication only to your skin, as directed by your doctor. Do not take it by mouth.
Avoid getting the medication in your mouth, nose, or eyes, as it may cause burning.
Unless instructed by your doctor, do not apply the medication to your face, underarms, or groin area.
Wash your hands before and after applying the medication. If the treated area is on your hand, do not wash your hand after application.
Clean the affected area before applying the medication and make sure it is dry.
Apply a thin layer of the medication to the affected skin and gently rub it in.
Do not cover the treated area with bandages or dressings unless instructed to do so by your doctor.
Storage and Disposal
Store the medication at room temperature.
Keep all medications in a safe place, out of the reach of children and pets.
Dispose of unused or expired medications properly. Do not flush them down the toilet or pour them down the drain unless instructed to do so. If you have questions about disposal, consult your pharmacist. You may also have access to drug take-back programs in your area.
Missed Dose
If you miss a dose, apply it as soon as you remember.
If it is close to the time for your next dose, skip the missed dose and resume your regular schedule.
* Do not apply two doses at the same time or use extra doses.
Lifestyle & Tips
- Wash your hands before and after applying the lotion.
- Apply a thin layer of the lotion to the affected skin area once daily, as directed by your doctor.
- Do not use more than the prescribed amount or apply more often than directed.
- Do not cover the treated area with bandages or other dressings unless specifically told to do so by your doctor, as this can increase absorption and side effects.
- Avoid applying the lotion to the face, groin, or armpits unless specifically instructed by your doctor.
- Avoid contact with eyes. If contact occurs, rinse thoroughly with water.
- Do not use this medication for longer than prescribed, especially in children, as prolonged use can lead to skin thinning or other side effects.
- Keep out of reach of children.
Available Forms & Alternatives
Available Strengths:
Generic Alternatives:
Dosing & Administration
Adult Dosing
Standard Dose:
Apply a thin film to the affected skin areas once daily.
Condition-Specific Dosing:
psoriasis:
Apply a thin film to the affected skin areas once daily.
atopicDermatitis:
Apply a thin film to the affected skin areas once daily.
Pediatric Dosing
Neonatal:
Not established (contraindicated for children under 2 years)
Infant:
Not established (contraindicated for children under 2 years)
Child:
For children 2 years of age or older, apply a thin film to the affected skin areas once daily. Limit treatment duration to the least amount of time necessary to achieve therapeutic effect. Avoid use on large surface areas or with occlusive dressings.
Adolescent:
Apply a thin film to the affected skin areas once daily.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Dialysis:
No specific considerations (minimal systemic absorption)
Hepatic Impairment:
Mild:
No adjustment needed (minimal systemic absorption)
Moderate:
No adjustment needed (minimal systemic absorption)
Severe:
No adjustment needed (minimal systemic absorption)
Pharmacology
Mechanism of Action
Mometasone furoate, a synthetic corticosteroid, exerts its therapeutic effects primarily through its anti-inflammatory, antipruritic, and vasoconstrictive properties. It acts by inducing phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption (approximately 0.4% with intact skin, increased with compromised skin barrier, occlusive dressings, or large surface areas)
Tmax:
Not applicable for topical local effect; systemic absorption peak is variable.
FoodEffect:
Not applicable (topical administration)
Distribution:
Vd:
Not applicable for topical local effect; systemically absorbed drug distributes widely.
ProteinBinding:
High (for systemically absorbed drug, typically >90%)
CnssPenetration:
Limited (for systemically absorbed drug)
Elimination:
HalfLife:
Not precisely determined for topical; systemically absorbed drug has variable half-life.
Clearance:
Not precisely determined for topical; systemically absorbed drug cleared renally and biliary.
ExcretionRoute:
Renal and biliary (for systemically absorbed drug)
Unchanged:
Minimal (for systemically absorbed drug)
Pharmacodynamics
OnsetOfAction:
Within hours to days (local anti-inflammatory effect)
PeakEffect:
Days to weeks (for full therapeutic effect)
DurationOfAction:
Up to 24 hours (with once-daily application)
Safety & Warnings
Side Effects
Serious Side Effects: Seek Medical Help Right Away
Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor immediately or seek medical attention:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of a weak adrenal gland, including:
+ Severe upset stomach or vomiting
+ Severe dizziness or fainting
+ Muscle weakness
+ Feeling extremely tired
+ Mood changes
+ Decreased appetite
+ Weight loss
Signs of Cushing's syndrome, such as:
+ Weight gain in the upper back or belly
+ Moon face
+ Severe headache
+ Slow healing
Signs of high blood sugar, including:
+ Confusion
+ Feeling sleepy
+ Unusual thirst or hunger
+ Passing urine more often
+ Flushing
+ Fast breathing
+ Breath that smells like fruit
Skin changes, such as:
+ Pimples
+ Stretch marks
+ Slow healing
+ Hair growth
Irritation at the site of application
Thinning of the skin
Changes in eyesight
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other symptoms that bother you or do not go away, contact your doctor:
Burning or stinging
Tingling
* Itching
This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor immediately or seek medical attention:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of a weak adrenal gland, including:
+ Severe upset stomach or vomiting
+ Severe dizziness or fainting
+ Muscle weakness
+ Feeling extremely tired
+ Mood changes
+ Decreased appetite
+ Weight loss
Signs of Cushing's syndrome, such as:
+ Weight gain in the upper back or belly
+ Moon face
+ Severe headache
+ Slow healing
Signs of high blood sugar, including:
+ Confusion
+ Feeling sleepy
+ Unusual thirst or hunger
+ Passing urine more often
+ Flushing
+ Fast breathing
+ Breath that smells like fruit
Skin changes, such as:
+ Pimples
+ Stretch marks
+ Slow healing
+ Hair growth
Irritation at the site of application
Thinning of the skin
Changes in eyesight
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other symptoms that bother you or do not go away, contact your doctor:
Burning or stinging
Tingling
* Itching
This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Increased redness, swelling, or pus at the application site (signs of infection)
- Severe burning, itching, or irritation that was not present before
- Thinning of the skin, easy bruising, or stretch marks in the treated area
- Changes in skin color (lightening or darkening)
- Acne-like rash or increased hair growth in the treated area
- If used extensively or for prolonged periods, watch for signs of systemic absorption such as unusual weight gain, swelling in ankles/feet, increased thirst/urination, or muscle weakness.
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is crucial to avoid potential interactions between this medication and other substances.
* Any existing health problems, as they may affect the safety and efficacy of this medication.
To ensure your safety, it is vital to verify that this medication can be taken with all your current medications and health conditions. Never start, stop, or adjust the dosage of any medication without first consulting your doctor. By sharing this information, you can help your doctor make informed decisions about your treatment and minimize potential risks.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced as a result of the allergy.
All medications you are currently taking, including prescription and over-the-counter (OTC) drugs, natural products, and vitamins. This is crucial to avoid potential interactions between this medication and other substances.
* Any existing health problems, as they may affect the safety and efficacy of this medication.
To ensure your safety, it is vital to verify that this medication can be taken with all your current medications and health conditions. Never start, stop, or adjust the dosage of any medication without first consulting your doctor. By sharing this information, you can help your doctor make informed decisions about your treatment and minimize potential risks.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.
Do not use this medication to treat diaper rash. If you are applying it to an area that will be covered by a diaper, avoid using tight-fitting diapers or plastic pants, as this can increase the amount of medication absorbed into the body. Some products may not be suitable for use in the diaper area, so consult your doctor before application.
Before using any other medications or skin products, including soaps, consult your doctor to ensure safe use. Avoid applying this medication to cuts, scrapes, or damaged skin. When using it on a large area of skin, exercise caution and discuss this with your doctor.
Do not exceed the prescribed duration of treatment. Prolonged use may increase the risk of developing cataracts or glaucoma, so consult your doctor about potential risks.
Note that different formulations of this medication may be intended for use in children of specific age groups. Before administering this medication to a child, consult your doctor to ensure you are using the correct formulation and to discuss potential risks. Children may be more susceptible to certain side effects, and this medication may affect growth in some cases. Regular growth checks may be necessary for children and teenagers using this medication.
If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor to discuss the potential benefits and risks to you and your baby.
Do not use this medication to treat diaper rash. If you are applying it to an area that will be covered by a diaper, avoid using tight-fitting diapers or plastic pants, as this can increase the amount of medication absorbed into the body. Some products may not be suitable for use in the diaper area, so consult your doctor before application.
Before using any other medications or skin products, including soaps, consult your doctor to ensure safe use. Avoid applying this medication to cuts, scrapes, or damaged skin. When using it on a large area of skin, exercise caution and discuss this with your doctor.
Do not exceed the prescribed duration of treatment. Prolonged use may increase the risk of developing cataracts or glaucoma, so consult your doctor about potential risks.
Note that different formulations of this medication may be intended for use in children of specific age groups. Before administering this medication to a child, consult your doctor to ensure you are using the correct formulation and to discuss potential risks. Children may be more susceptible to certain side effects, and this medication may affect growth in some cases. Regular growth checks may be necessary for children and teenagers using this medication.
If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor to discuss the potential benefits and risks to you and your baby.
Overdose Information
Overdose Symptoms:
- Prolonged or excessive use of topical corticosteroids can lead to systemic effects, including suppression of the hypothalamic-pituitary-adrenal (HPA) axis, Cushing's syndrome, hyperglycemia, and glucosuria. Symptoms may include: fatigue, weakness, nausea, vomiting, low blood pressure, weight gain, moon face, central obesity, stretch marks, and high blood sugar.
What to Do:
If you suspect an overdose or experience systemic symptoms, contact your doctor or a poison control center immediately. Call 1-800-222-1222 for the Poison Control Center. Management typically involves gradual withdrawal of the corticosteroid and supportive care.
Drug Interactions
Monitoring
Baseline Monitoring
Skin condition assessment
Rationale: To establish baseline severity of dermatosis and identify any pre-existing skin infections or atrophy.
Timing: Prior to initiation of therapy
Routine Monitoring
Efficacy (reduction in inflammation, pruritus)
Frequency: Regularly during treatment (e.g., weekly or bi-weekly)
Target: Improvement in symptoms
Action Threshold: Lack of improvement or worsening symptoms may require re-evaluation of diagnosis or treatment.
Local adverse reactions (e.g., atrophy, striae, telangiectasias, folliculitis, burning, itching)
Frequency: Regularly during treatment
Target: Absence or minimal
Action Threshold: Presence of significant local adverse effects may require discontinuation or change in therapy.
Signs of HPA axis suppression (especially with prolonged use, large areas, or occlusive dressings)
Frequency: Periodically, especially in pediatric patients or with extensive use
Target: Normal cortisol levels
Action Threshold: Symptoms like fatigue, weight loss, hypotension, or abnormal cortisol levels may require systemic evaluation and gradual withdrawal.
Symptom Monitoring
- Burning
- Itching
- Irritation
- Dryness
- Folliculitis
- Hypertrichosis
- Acneiform eruptions
- Hypopigmentation
- Perioral dermatitis
- Allergic contact dermatitis
- Maceration of the skin
- Secondary infection
- Skin atrophy
- Striae
- Miliaria
- Signs of Cushing's syndrome (e.g., moon face, central obesity, striae, hypertension)
- Signs of adrenal insufficiency (e.g., fatigue, weakness, nausea, vomiting, hypotension)
Special Patient Groups
Pregnancy
Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Mometasone furoate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Trimester-Specific Risks:
First Trimester:
Potential for teratogenicity observed in animal studies at high doses; human data limited.
Second Trimester:
Risk of HPA axis suppression in the fetus with extensive maternal use.
Third Trimester:
Risk of HPA axis suppression in the fetus with extensive maternal use; potential for low birth weight.
Lactation
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Caution should be exercised when Elocon Lotion is administered to a nursing woman. Avoid applying to the breast area to prevent infant ingestion.
Infant Risk:
Low risk with appropriate use (minimal systemic absorption), but potential for adverse effects if significant systemic absorption occurs or if applied to areas where infant may ingest.
Pediatric Use
Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio. Use in children under 2 years of age is contraindicated. Use in older children should be limited to the least amount necessary for therapeutic effect and for the shortest duration. Monitor for signs of systemic toxicity.
Geriatric Use
No overall differences in safety or effectiveness were observed between elderly subjects and younger subjects. However, elderly patients may have thinner skin and be more prone to skin atrophy, so monitor carefully.
Clinical Information
Clinical Pearls
- Elocon Lotion is a high-potency topical corticosteroid. Use it sparingly and only on affected areas.
- Do not use this lotion on the face, groin, or armpits unless specifically instructed by a dermatologist, as these areas are more susceptible to side effects like skin thinning.
- Avoid prolonged continuous use, especially in children, to minimize the risk of skin atrophy and systemic side effects like HPA axis suppression.
- If no improvement is seen after 2 weeks of treatment, re-evaluate the diagnosis and treatment plan.
- Patients should be advised to report any signs of local adverse reactions or systemic effects to their healthcare provider.
- This formulation is a lotion, which is often preferred for hairy areas or large surface areas due to its ease of spreading and less greasy feel compared to creams or ointments.
Alternative Therapies
- Other topical corticosteroids (e.g., clobetasol, fluocinonide, triamcinolone, hydrocortisone)
- Topical calcineurin inhibitors (e.g., tacrolimus, pimecrolimus) for atopic dermatitis
- Topical vitamin D analogs (e.g., calcipotriene) for psoriasis
- Topical retinoids (e.g., tazarotene) for psoriasis
- Emollients and moisturizers for dry skin conditions
- Systemic therapies (e.g., biologics, oral immunosuppressants) for severe cases
Cost & Coverage
Average Cost:
$50 - $200 per 30ml bottle
Generic Available:
Yes
Insurance Coverage:
Tier 2 or 3 (Brand), Tier 1 (Generic)
General Drug Facts
If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about this medication, don't hesitate to discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.