Docetaxel 160mg/16ml Inj, 16ml
WARNING: Severe and sometimes deadly allergic reactions have happened with this drug. Do not take this drug if you have ever had an allergic reaction to it.Some of these products have polysorbate 80. If you are allergic to polysorbate 80, talk with your doctor about whether your product has polysorbate 80 in it.The risk of death that may rarely happen with this drug is raised in people with liver problems and in people who get high doses of this drug. The risk is also raised in people with a certain type of lung cancer who have been treated with a platinum-based chemo drug in the past. This drug must not be given to some people with high bilirubin levels, liver problems, or raised liver enzymes. If you have any of these health problems or any questions, talk with your doctor.This drug may cause you to swell or keep fluid in your body. Tell your doctor if you have swelling, weight gain, or trouble breathing.Low blood cell counts have happened with this drug. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Sometimes, these have been deadly. If you have questions, talk with the doctor.Have your blood work and other lab tests checked as you have been told by your doctor. If you have a low white blood cell count, talk with your doctor. This drug must not be used in certain people with low white blood cell counts. @ COMMON USES: It is used to treat cancer.
Drug Class
See FDA label
Overview
How to Use This Medicine
Taking Your Medication Correctly
To ensure safe and effective use of this medication, follow your doctor's instructions carefully. Read all the information provided to you and adhere to the instructions closely. This medication is administered as an intravenous infusion over a specified period.
To minimize the risk of severe side effects, a steroid medication like dexamethasone will be given before administering this drug. However, please note that this precaution may not completely eliminate the risk of side effects in all individuals. It is essential to discuss this with your doctor. If you are not given the steroid medication as directed, inform your doctor promptly.
Before receiving this medication, it is crucial to ensure you are not dehydrated. Consult your doctor to determine if you need to drink additional fluids before the infusion.
Storing and Disposing of Your Medication
If you need to store this medication at home, consult your doctor, nurse, or pharmacist for guidance on proper storage procedures.
Missing a Dose
If you miss a dose, contact your doctor immediately to determine the best course of action.
To ensure safe and effective use of this medication, follow your doctor's instructions carefully. Read all the information provided to you and adhere to the instructions closely. This medication is administered as an intravenous infusion over a specified period.
To minimize the risk of severe side effects, a steroid medication like dexamethasone will be given before administering this drug. However, please note that this precaution may not completely eliminate the risk of side effects in all individuals. It is essential to discuss this with your doctor. If you are not given the steroid medication as directed, inform your doctor promptly.
Before receiving this medication, it is crucial to ensure you are not dehydrated. Consult your doctor to determine if you need to drink additional fluids before the infusion.
Storing and Disposing of Your Medication
If you need to store this medication at home, consult your doctor, nurse, or pharmacist for guidance on proper storage procedures.
Missing a Dose
If you miss a dose, contact your doctor immediately to determine the best course of action.
Available Forms & Alternatives
Dosing & Administration
Pharmacology
Safety & Warnings
Side Effects
Urgent Side Effects: Seek Medical Help Immediately
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention right away:
Allergic reactions: Rash, hives, itching, red, swollen, blistered, or peeling skin with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Infections: Fever, chills, severe sore throat, ear or sinus pain, cough, increased sputum production or change in sputum color, painful urination, mouth sores, or a wound that won't heal.
Bleeding: Vomiting or coughing up blood, coffee ground-like vomit, blood in the urine, black, red, or tarry stools, bleeding gums, abnormal vaginal bleeding, unexplained bruises or bruises that get bigger, or uncontrollable bleeding.
Lung or breathing problems: Shortness of breath or other breathing difficulties, cough, or fever.
Dizziness or fainting
Abnormal heartbeat
Numbness, tingling, or burning sensations that are not normal
Muscle weakness
Additional Important Warnings
This medication can cause tissue damage if it leaks from the vein. Inform your nurse immediately if you experience redness, burning, pain, swelling, blisters, skin sores, or fluid leakage at the injection site.
This medication may cause cystoid macular edema (CME), a specific eye problem. You may need regular eye exams while taking this medication. Contact your doctor right away if you experience blurred vision or loss of vision.
This medication can cause severe bowel problems, which can be life-threatening. Seek medical attention immediately if you experience stomach pain with or without fever, tender stomach, or diarrhea.
Liver problems have occurred rarely with this medication, sometimes with fatal outcomes. Contact your doctor right away if you experience dark urine, fatigue, decreased appetite, nausea, stomach pain, light-colored stools, vomiting, or yellow skin or eyes.
This medication may cause tumor lysis syndrome (TLS), a severe health condition that can lead to death. Seek medical attention immediately if you experience fast or abnormal heartbeat, fainting, difficulty urinating, muscle weakness or cramps, nausea, vomiting, diarrhea, or loss of appetite. Discuss ways to prevent TLS with your doctor.
Severe skin reactions, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and other severe skin reactions, have occurred with this medication. Seek medical attention immediately if you experience red, swollen, blistered, or peeling skin, skin irritation with or without fever, red or irritated eyes, or sores in your mouth, throat, nose, or eyes.
Common Side Effects
While many people may not experience side effects or may only have mild side effects, it's essential to be aware of the following:
Mouth irritation or mouth sores
Changes in nail color or texture
Changes in taste
Muscle or joint pain
Flushing
Eye redness
Excessive tearing
Weight loss
Menstrual changes
Constipation, diarrhea, nausea, vomiting, or decreased appetite (common side effects that can be managed with your doctor's guidance)
Hair loss (usually temporary, but in some cases, hair growth may not return to normal)
Fatigue or weakness (may last from a few days to several weeks)
If any of these side effects bother you, do not improve, or are severe, contact your doctor for guidance.
Reporting Side Effects
If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
While rare, some people may experience severe and potentially life-threatening side effects when taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical attention right away:
Allergic reactions: Rash, hives, itching, red, swollen, blistered, or peeling skin with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat.
Infections: Fever, chills, severe sore throat, ear or sinus pain, cough, increased sputum production or change in sputum color, painful urination, mouth sores, or a wound that won't heal.
Bleeding: Vomiting or coughing up blood, coffee ground-like vomit, blood in the urine, black, red, or tarry stools, bleeding gums, abnormal vaginal bleeding, unexplained bruises or bruises that get bigger, or uncontrollable bleeding.
Lung or breathing problems: Shortness of breath or other breathing difficulties, cough, or fever.
Dizziness or fainting
Abnormal heartbeat
Numbness, tingling, or burning sensations that are not normal
Muscle weakness
Additional Important Warnings
This medication can cause tissue damage if it leaks from the vein. Inform your nurse immediately if you experience redness, burning, pain, swelling, blisters, skin sores, or fluid leakage at the injection site.
This medication may cause cystoid macular edema (CME), a specific eye problem. You may need regular eye exams while taking this medication. Contact your doctor right away if you experience blurred vision or loss of vision.
This medication can cause severe bowel problems, which can be life-threatening. Seek medical attention immediately if you experience stomach pain with or without fever, tender stomach, or diarrhea.
Liver problems have occurred rarely with this medication, sometimes with fatal outcomes. Contact your doctor right away if you experience dark urine, fatigue, decreased appetite, nausea, stomach pain, light-colored stools, vomiting, or yellow skin or eyes.
This medication may cause tumor lysis syndrome (TLS), a severe health condition that can lead to death. Seek medical attention immediately if you experience fast or abnormal heartbeat, fainting, difficulty urinating, muscle weakness or cramps, nausea, vomiting, diarrhea, or loss of appetite. Discuss ways to prevent TLS with your doctor.
Severe skin reactions, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and other severe skin reactions, have occurred with this medication. Seek medical attention immediately if you experience red, swollen, blistered, or peeling skin, skin irritation with or without fever, red or irritated eyes, or sores in your mouth, throat, nose, or eyes.
Common Side Effects
While many people may not experience side effects or may only have mild side effects, it's essential to be aware of the following:
Mouth irritation or mouth sores
Changes in nail color or texture
Changes in taste
Muscle or joint pain
Flushing
Eye redness
Excessive tearing
Weight loss
Menstrual changes
Constipation, diarrhea, nausea, vomiting, or decreased appetite (common side effects that can be managed with your doctor's guidance)
Hair loss (usually temporary, but in some cases, hair growth may not return to normal)
Fatigue or weakness (may last from a few days to several weeks)
If any of these side effects bother you, do not improve, or are severe, contact your doctor for guidance.
Reporting Side Effects
If you have questions or concerns about side effects, contact your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced.
If you are currently taking any of the following medications: atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole.
If you are breastfeeding. Note that you should not breastfeed while taking this medication and for 1 week after your last dose.
Please be aware that this is not an exhaustive list of all potential interactions with this medication. To ensure your safety, it is crucial to:
Inform your doctor and pharmacist about all the medications you are taking, including prescription and over-the-counter drugs, natural products, and vitamins.
Share information about your health problems.
Verify that it is safe to take this medication with your other medications and health conditions.
* Never start, stop, or change the dose of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the symptoms you experienced.
If you are currently taking any of the following medications: atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole.
If you are breastfeeding. Note that you should not breastfeed while taking this medication and for 1 week after your last dose.
Please be aware that this is not an exhaustive list of all potential interactions with this medication. To ensure your safety, it is crucial to:
Inform your doctor and pharmacist about all the medications you are taking, including prescription and over-the-counter drugs, natural products, and vitamins.
Share information about your health problems.
Verify that it is safe to take this medication with your other medications and health conditions.
* Never start, stop, or change the dose of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. If you are prescribed other medications in addition to this one, make sure you understand their warnings, benefits, and risks. Discuss any questions or concerns you have about these medications with your doctor.
To ensure your safety, avoid driving and other activities that require alertness and clear vision until you know how this medication affects you. Be aware that this medication contains alcohol, which may cause feelings of intoxication during and after treatment. If you experience confusion, dizziness, stumbling, or excessive sleepiness during or within 1 to 2 hours after treatment, notify your doctor. Before consuming alcohol, using marijuana or other cannabis products, or taking prescription or over-the-counter medications that may impair your actions, consult with your doctor.
As this medication may increase your risk of infection, practice good hygiene by washing your hands frequently and avoiding close contact with people who have infections, colds, or flu. Additionally, you may be more prone to bleeding, so be cautious and avoid injuries. Use a soft toothbrush and an electric razor to minimize the risk of bleeding.
Before receiving any vaccinations, consult with your doctor, as some vaccines may not be effective or may increase the risk of infection when taken with this medication. Although rare, it is possible for other cancers, including certain blood cancers and kidney cancer, to develop in people taking this medication, especially when combined with other cancer treatments. This risk may occur months to years after treatment, so discuss any concerns you have with your doctor.
Some formulations of this medication contain albumin, a component of blood, which may carry a risk of viral transmission. However, the medication is thoroughly screened, tested, and treated to minimize this risk. If you have questions or concerns, discuss them with your doctor.
If you are 65 or older, use this medication with caution, as you may be more susceptible to side effects. This medication may also affect fertility in men, so discuss this with your doctor if you have concerns about fathering a child. Furthermore, this medication may harm an unborn baby, so a pregnancy test will be performed before you start treatment to confirm that you are not pregnant.
If you or your partner may become pregnant, it is crucial to use birth control while taking this medication and for a specified period after the last dose. Your doctor will advise you on the duration of birth control use. If you or your partner becomes pregnant, notify your doctor immediately.
To ensure your safety, avoid driving and other activities that require alertness and clear vision until you know how this medication affects you. Be aware that this medication contains alcohol, which may cause feelings of intoxication during and after treatment. If you experience confusion, dizziness, stumbling, or excessive sleepiness during or within 1 to 2 hours after treatment, notify your doctor. Before consuming alcohol, using marijuana or other cannabis products, or taking prescription or over-the-counter medications that may impair your actions, consult with your doctor.
As this medication may increase your risk of infection, practice good hygiene by washing your hands frequently and avoiding close contact with people who have infections, colds, or flu. Additionally, you may be more prone to bleeding, so be cautious and avoid injuries. Use a soft toothbrush and an electric razor to minimize the risk of bleeding.
Before receiving any vaccinations, consult with your doctor, as some vaccines may not be effective or may increase the risk of infection when taken with this medication. Although rare, it is possible for other cancers, including certain blood cancers and kidney cancer, to develop in people taking this medication, especially when combined with other cancer treatments. This risk may occur months to years after treatment, so discuss any concerns you have with your doctor.
Some formulations of this medication contain albumin, a component of blood, which may carry a risk of viral transmission. However, the medication is thoroughly screened, tested, and treated to minimize this risk. If you have questions or concerns, discuss them with your doctor.
If you are 65 or older, use this medication with caution, as you may be more susceptible to side effects. This medication may also affect fertility in men, so discuss this with your doctor if you have concerns about fathering a child. Furthermore, this medication may harm an unborn baby, so a pregnancy test will be performed before you start treatment to confirm that you are not pregnant.
If you or your partner may become pregnant, it is crucial to use birth control while taking this medication and for a specified period after the last dose. Your doctor will advise you on the duration of birth control use. If you or your partner becomes pregnant, notify your doctor immediately.
Drug Interactions
Monitoring
Special Patient Groups
Clinical Information
General Drug Facts
If your symptoms or health problems persist or worsen, it is essential to contact your doctor for further guidance. To ensure safe use, never share your medication with others, and do not take medication prescribed to someone else. Store all medications in a secure location, out of reach of children and pets, to prevent accidental ingestion. Dispose of unused or expired medications properly: do not flush them down the toilet or pour them down the drain unless instructed to do so by your pharmacist or healthcare provider. If you are unsure about the correct disposal method, consult your pharmacist, who can also inform you about potential drug take-back programs in your area. Some medications may come with an additional patient information leaflet, which your pharmacist can provide. If you have any questions or concerns about your medication, discuss them with your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately contact your local poison control center or seek medical attention. Be prepared to provide information about the medication taken, the amount, and the time it occurred to ensure prompt and effective treatment.