Dermazinc Cream 120gm
It is used to treat or prevent certain skin problems.It may be given to you for other reasons. Talk with the doctor.
Drug Class
Skin Protectant; Moisturizer
Pharmacologic Class
Emollient
Pregnancy Category
Category A
FDA Approved
Jan 1970
DEA Schedule
Not Controlled
Overview
What is this medicine?
Emollients are moisturizers that help to soften and smooth your skin by creating a protective barrier that locks in moisture. They are used to treat dry, itchy, or scaly skin conditions.
How to Use This Medicine
Proper Use of This Medication
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication only as directed.
Application Instructions
Do not take this medication by mouth. It is for skin use only.
Avoid getting the medication in your mouth, nose, ears, or eyes, as it may cause burning.
If your medication requires shaking before use, make sure to do so before applying it to the affected area.
Wash your hands before and after applying the medication, unless your hand is the treated area. In this case, do not wash your hand after application.
Clean the affected area before applying the medication and dry it thoroughly.
Apply the medication to the affected area as instructed by your doctor. You may need to cover the treated area with a bandage or dressing; consult with your doctor for guidance.
Storage and Disposal
Store the medication at room temperature and do not freeze it.
Check the storage information provided with the medication to determine how long it can be stored before disposal. If you have questions, consult with your pharmacist.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not use it more frequently than instructed by your doctor.
To use this medication correctly, follow your doctor's instructions and read all the information provided. It is essential to use this medication only as directed.
Application Instructions
Do not take this medication by mouth. It is for skin use only.
Avoid getting the medication in your mouth, nose, ears, or eyes, as it may cause burning.
If your medication requires shaking before use, make sure to do so before applying it to the affected area.
Wash your hands before and after applying the medication, unless your hand is the treated area. In this case, do not wash your hand after application.
Clean the affected area before applying the medication and dry it thoroughly.
Apply the medication to the affected area as instructed by your doctor. You may need to cover the treated area with a bandage or dressing; consult with your doctor for guidance.
Storage and Disposal
Store the medication at room temperature and do not freeze it.
Check the storage information provided with the medication to determine how long it can be stored before disposal. If you have questions, consult with your pharmacist.
Missed Dose
If you miss a dose, apply it as soon as you remember.
Since this medication is often used as needed, do not use it more frequently than instructed by your doctor.
Lifestyle & Tips
- Apply to damp skin after bathing or showering to maximize moisture retention.
- Use regularly, even when skin feels better, to maintain hydration.
- Avoid harsh soaps or cleansers that can strip natural skin oils.
- Wear loose, breathable clothing to prevent skin irritation.
Available Forms & Alternatives
Available Strengths:
Dosing & Administration
Adult Dosing
Standard Dose:
Apply a thin layer to affected skin areas 2-3 times daily or as needed.
Condition-Specific Dosing:
dryness:
Apply liberally as often as needed, especially after bathing.
Pediatric Dosing
Neonatal:
Apply as directed by a healthcare professional, generally safe for topical use.
Infant:
Apply as directed by a healthcare professional, generally safe for topical use.
Child:
Apply as directed by a healthcare professional, generally safe for topical use.
Adolescent:
Apply a thin layer to affected skin areas 2-3 times daily or as needed.
Dose Adjustments
Renal Impairment:
Mild:
No adjustment needed
Moderate:
No adjustment needed
Severe:
No adjustment needed
Dialysis:
No specific considerations for topical application
Hepatic Impairment:
Mild:
No adjustment
Moderate:
No adjustment
Severe:
No adjustment
Pharmacology
Mechanism of Action
Emollients work by forming an occlusive film on the skin surface, which reduces transepidermal water loss (TEWL) and helps to rehydrate the stratum corneum. They fill in the spaces between desquamating corneocytes, smoothing the skin and restoring barrier function. Some emollients also contain humectants (e.g., glycerin) that attract water from the dermis and epidermis, further increasing skin hydration.
Pharmacokinetics
Absorption:
Bioavailability:
Minimal systemic absorption
Tmax:
Not applicable (topical action)
FoodEffect:
Not applicable
Distribution:
Vd:
Not applicable (localized action)
ProteinBinding:
Not applicable
CnssPenetration:
No
Elimination:
HalfLife:
Not applicable
Clearance:
Not applicable
ExcretionRoute:
Not applicable
Unchanged:
Not applicable
Pharmacodynamics
OnsetOfAction:
Immediate (upon application)
PeakEffect:
Within minutes to hours (hydration effect)
DurationOfAction:
Hours, depending on product and activity level
Safety & Warnings
Side Effects
Serious Side Effects: Seek Medical Help Immediately
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek medical attention right away:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of skin infection, including:
+ Oozing
+ Heat
+ Swelling
+ Redness
+ Pain
Abnormal bleeding from the affected area
Fever
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or do not go away, contact your doctor:
* Skin irritation
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Although rare, this medication can cause severe and potentially life-threatening side effects. If you experience any of the following symptoms, contact your doctor or seek medical attention right away:
Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of skin infection, including:
+ Oozing
+ Heat
+ Swelling
+ Redness
+ Pain
Abnormal bleeding from the affected area
Fever
Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other unusual symptoms that bother you or do not go away, contact your doctor:
* Skin irritation
Reporting Side Effects
This list is not exhaustive, and you may experience other side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
Seek Immediate Medical Attention If You Experience:
- Increased redness or irritation at the application site
- New rash or hives
- Swelling of the face, lips, or tongue (signs of allergic reaction)
- Signs of infection (pus, severe pain, fever)
Before Using This Medicine
Before Taking This Medication: Important Information to Share with Your Doctor
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction and its symptoms.
If you have a skin rash caused by an allergic reaction to a food or medication.
* If you have a bleeding wound.
This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions.
Remember, do not start, stop, or change the dose of any medication without first consulting your doctor.
It is essential to inform your doctor about the following:
Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Be sure to describe the allergic reaction and its symptoms.
If you have a skin rash caused by an allergic reaction to a food or medication.
* If you have a bleeding wound.
This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other medications and health conditions.
Remember, do not start, stop, or change the dose of any medication without first consulting your doctor.
Precautions & Cautions
It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication.
Before using sunscreen with this drug, consult your doctor for guidance. Additionally, discuss with your doctor any other medications or products you plan to use on your skin, including soaps, to ensure safe use.
Certain brands of this medication may not be suitable for application on open sores, broken skin, or severe burns. Be sure to check with your doctor or pharmacist for specific instructions.
Some products containing this drug may include metal, which must be removed before undergoing an MRI, cardioversion, radiation, or other medical procedures. It is crucial to discuss this with your doctor before any scheduled procedures.
If this medication is accidentally swallowed, it can cause harm. In such an event, immediately contact a doctor or a poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby.
Before using sunscreen with this drug, consult your doctor for guidance. Additionally, discuss with your doctor any other medications or products you plan to use on your skin, including soaps, to ensure safe use.
Certain brands of this medication may not be suitable for application on open sores, broken skin, or severe burns. Be sure to check with your doctor or pharmacist for specific instructions.
Some products containing this drug may include metal, which must be removed before undergoing an MRI, cardioversion, radiation, or other medical procedures. It is crucial to discuss this with your doctor before any scheduled procedures.
If this medication is accidentally swallowed, it can cause harm. In such an event, immediately contact a doctor or a poison control center for assistance.
If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of this medication to both you and your baby.
Overdose Information
Overdose Symptoms:
- Topical overdose is unlikely to cause systemic effects.
- Excessive application may lead to a greasy feeling or clogged pores.
What to Do:
Wipe off excess product. If ingested, generally considered non-toxic, but contact a poison control center (1-800-222-1222) if large amounts are swallowed or if symptoms develop.
Drug Interactions
Monitoring
Routine Monitoring
Skin hydration and integrity
Frequency: Daily
Target: Improved skin texture, reduced dryness/itching
Action Threshold: Worsening dryness, irritation, or lack of improvement may indicate need for different product or medical evaluation.
Symptom Monitoring
- Skin irritation
- Redness
- Itching
- Burning sensation
- Allergic reaction (rash, swelling)
Special Patient Groups
Pregnancy
Generally considered safe for use during pregnancy. Minimal systemic absorption is expected.
Trimester-Specific Risks:
First Trimester:
Low risk
Second Trimester:
Low risk
Third Trimester:
Low risk
Lactation
Generally considered safe for use during lactation. Minimal systemic absorption is expected. Avoid applying to areas where the infant may ingest the product (e.g., nipples) without first wiping off.
Infant Risk:
Low risk
Pediatric Use
Generally safe and effective for use in infants, children, and adolescents for dry skin conditions. Always consult a pediatrician for specific guidance, especially for very young infants or severe conditions.
Geriatric Use
Generally safe and effective for use in geriatric patients. Older adults often have drier skin and may benefit significantly from regular emollient use.
Clinical Information
Clinical Pearls
- Apply emollients liberally and frequently, especially after bathing, to maximize their effectiveness.
- Different emollient formulations (creams, lotions, ointments) offer varying degrees of hydration and greasiness; choose based on skin dryness and patient preference.
- Ointments are typically more occlusive and hydrating, suitable for very dry or thickened skin.
- Creams are a good balance of hydration and cosmetic acceptability.
- Lotions are lighter and spread easily, suitable for less dry or hairy areas.
- For optimal results, apply within 3 minutes of bathing to 'trap' moisture in the skin.
Alternative Therapies
- Topical corticosteroids (for inflammatory skin conditions)
- Topical calcineurin inhibitors (for inflammatory skin conditions)
- Antipruritics (e.g., pramoxine, menthol, camphor)
- Barrier repair creams
Cost & Coverage
Average Cost:
Varies widely ($5 - $30+) per 120gm tube
Generic Available:
Yes
Insurance Coverage:
OTC (Over-the-Counter), generally not covered by prescription plans unless prescribed for specific conditions and formulary allows.
General Drug Facts
If your symptoms or health issues persist or worsen, it's essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so be sure to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.