Corvite 150 Tablets

Manufacturer VERTICAL PHARMACEUTICAL Active Ingredient Vitamins (Multiple/Oral)(VYE ta mins, MUL ti pul/OR al) Pronunciation VYE-ta-mins, MUL-ti-pul/OR-al
WARNING: If your product has iron in it:Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep away from children. If this drug is taken by accident, call a doctor or poison control center right away. @ COMMON USES: It is used to help growth and good health.It may be given to you for other reasons. Talk with the doctor.
đŸˇī¸
Drug Class
Nutritional Supplement; Vitamin
đŸ§Ŧ
Pharmacologic Class
Vitamin Supplement; Micronutrient
🤰
Pregnancy Category
Category A (for typical doses meeting RDA); Category C (for doses exceeding RDA or specific vitamins)
✅
FDA Approved
Jan 1970
âš–ī¸
DEA Schedule
Not Controlled

Overview

â„šī¸

What is this medicine?

Corvite 150 Tablets are a multivitamin supplement containing a combination of essential vitamins and minerals. They are used to provide nutrients that may be missing from your diet or to help meet increased nutritional needs, supporting overall health and well-being.
📋

How to Use This Medicine

Taking Your Medication Correctly

To get the most benefit from your medication, follow your doctor's instructions carefully. Read all the information provided with your medication and follow the instructions closely.

Administration Instructions

You can take this medication with or without food. If it causes stomach upset, take it with food to help minimize discomfort.
For optimal absorption, take this medication at bedtime. If you have questions about the best time to take your medication, consult with your doctor or pharmacist.

Special Instructions for Extended-Release Products

Swallow extended-release tablets or capsules whole. Do not chew, break, or crush them, as this can alter the release of the medication.

Measuring Liquid Medication

When taking liquid medication, measure the dose carefully using the measuring device provided with the medication. If a measuring device is not included, ask your pharmacist for one to ensure accurate dosing.

Chewable Tablets

Chew chewable tablets thoroughly before swallowing to ensure proper absorption.

Storing and Disposing of Your Medication

Store your medication at room temperature in a dry place, away from the bathroom.
Protect your medication from heat and light to preserve its potency.
Keep all medications in a safe location, out of the reach of children and pets.

What to Do If You Miss a Dose

If you miss a dose, take it as soon as you remember.
If it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
* Do not take two doses at the same time or take extra doses, as this can increase the risk of side effects.
💡

Lifestyle & Tips

  • Take with food to improve absorption and reduce stomach upset.
  • Do not exceed the recommended dose unless directed by a healthcare professional.
  • Multivitamins are supplements and should not replace a balanced and varied diet.
  • Store in a cool, dry place away from direct light and moisture, out of reach of children.
💊

Available Forms & Alternatives

Dosing & Administration

đŸ‘¨â€âš•ī¸

Adult Dosing

Standard Dose: One tablet daily, or as directed by a healthcare professional.
Dose Range: 1 - 2 mg

Condition-Specific Dosing:

general_health: One tablet daily with food.
deficiency_states: Higher doses may be prescribed by a physician based on specific vitamin deficiencies.
đŸ‘ļ

Pediatric Dosing

Neonatal: Not established (specific infant formulations are available)
Infant: Not established (specific infant formulations are available)
Child: Consult a pediatrician; typically not recommended for young children unless specifically formulated or prescribed.
Adolescent: One tablet daily, or as directed by a healthcare professional, if formulation is appropriate for age.
âš•ī¸

Dose Adjustments

Renal Impairment:

Mild: No specific adjustment typically needed for standard doses.
Moderate: Caution advised with fat-soluble vitamins (A, D, E, K) due to potential accumulation. Monitor levels if high doses are used.
Severe: Caution advised, especially with fat-soluble vitamins and Vitamin C (oxalate formation). Consult nephrologist. Avoid high doses.
Dialysis: Specific vitamin supplementation may be required, but general multivitamins should be used with caution and under medical supervision.

Hepatic Impairment:

Mild: No specific adjustment typically needed for standard doses.
Moderate: Caution advised with fat-soluble vitamins (A, D, E, K) due to impaired metabolism and storage. Monitor levels if high doses are used.
Severe: Caution advised, especially with fat-soluble vitamins. Avoid high doses. Consult hepatologist.

Pharmacology

đŸ”Ŧ

Mechanism of Action

Vitamins are essential organic compounds required in small quantities for normal metabolic function, growth, and overall health. They act as coenzymes, antioxidants, hormones, or structural components, participating in various biochemical reactions necessary for energy production, immune function, cell growth and repair, vision, bone health, and blood clotting.
📊

Pharmacokinetics

Absorption:

Bioavailability: Variable (depends on specific vitamin, formulation, presence of food, and individual absorption capacity). Water-soluble vitamins (B, C) are generally well-absorbed but not stored. Fat-soluble vitamins (A, D, E, K) require dietary fat for absorption and are stored in the body.
Tmax: Variable (typically 1-8 hours, depending on specific vitamin and formulation)
FoodEffect: Generally enhanced absorption for fat-soluble vitamins when taken with food containing fat. May improve tolerance for some water-soluble vitamins.

Distribution:

Vd: Variable (depends on specific vitamin; water-soluble vitamins distribute throughout body water, fat-soluble vitamins distribute into adipose tissue and liver)
ProteinBinding: Variable (e.g., Vitamin D binds to DBP, Vitamin A to RBP, Vitamin B12 to transcobalamins)
CnssPenetration: Limited for some, Yes for others (e.g., B vitamins, Vitamin C)

Elimination:

HalfLife: Variable (minutes to days for water-soluble; days to months for fat-soluble)
Clearance: Variable (renal for water-soluble; biliary/fecal for fat-soluble)
ExcretionRoute: Renal (water-soluble vitamins); Biliary/Fecal (fat-soluble vitamins)
Unchanged: Variable (significant portion of water-soluble vitamins may be excreted unchanged)
âąī¸

Pharmacodynamics

OnsetOfAction: Physiological effects are gradual and cumulative, not acute. Correction of deficiency symptoms may take days to weeks.
PeakEffect: Not applicable in an acute sense; refers to sustained physiological levels achieved with consistent supplementation.
DurationOfAction: Depends on the specific vitamin's half-life and storage capacity; water-soluble vitamins require daily intake, fat-soluble vitamins can be stored for longer periods.

Safety & Warnings

âš ī¸

Side Effects

Urgent Side Effects: Seek Medical Attention Immediately
Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek medical help right away:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
If your product contains iron:
+ Black, tarry, or bloody stools
+ Fever
+ Vomiting blood or coffee ground-like material
+ Stomach cramps

Other Possible Side Effects
Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or if they persist or bother you, contact your doctor:

Common to all products:
+ Upset stomach or vomiting
If your product contains iron:
+ Diarrhea or constipation
+ Change in stool color to green
+ Stomach pain

Important Note
This list is not exhaustive, and you may experience other side effects not mentioned here. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.
🚨

Seek Immediate Medical Attention If You Experience:

  • Severe stomach upset, nausea, vomiting, or diarrhea.
  • Unusual fatigue or weakness.
  • Headache or dizziness.
  • Skin rash or itching.
  • Yellowing of skin or eyes (jaundice).
  • Changes in urine color (e.g., very dark urine).
  • Signs of allergic reaction (swelling of face/throat, difficulty breathing).
📋

Before Using This Medicine

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following conditions to ensure safe treatment:

Any allergies you have, including allergies to this medication, its components, or other substances. Be sure to describe the symptoms you experienced.
Certain types of anemia, such as pernicious anemia, which is characterized by a lack of vitamin B12 in the body.
If you are currently taking levodopa.
If you are taking mineral oil.
* If your medication contains iron:
+ If you have an excessive amount of iron in your body (iron overload).
+ If you have hemolytic anemia, a condition where red blood cells are destroyed faster than they can be made.

This list is not exhaustive, and it is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health conditions with your doctor and pharmacist. They will help determine if it is safe to take this medication with your other treatments. Never start, stop, or adjust the dosage of any medication without consulting your doctor first.
âš ī¸

Precautions & Cautions

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This drug may interfere with certain laboratory tests, so be sure to notify your healthcare providers and laboratory personnel that you are taking it.

If you have a soy allergy, consult with your doctor before taking this medication, as some products may contain soy. Additionally, if you are allergic to tartrazine (also known as FD&C Yellow No. 5), discuss this with your doctor, as some products may contain this ingredient.

When considering administering this medication to a child, it is crucial to consult with the doctor first, as different brands of this drug may be approved for use in children of varying ages.

If you are pregnant, planning to become pregnant, or are breastfeeding, inform your doctor. You and your doctor will need to discuss the potential benefits and risks of taking this medication to ensure the best outcome for both you and your baby.
🆘

Overdose Information

Overdose Symptoms:

  • Nausea, vomiting, diarrhea, abdominal pain.
  • Headache, dizziness, blurred vision.
  • Fatigue, muscle weakness.
  • Hair loss, dry skin, cracked lips (Vitamin A toxicity).
  • Bone pain, kidney stones, excessive thirst/urination (Vitamin D toxicity).
  • Nerve damage, tingling, numbness (Vitamin B6 toxicity).
  • Increased bleeding/bruising (Vitamin E toxicity).
  • Iron poisoning (especially in children, can be fatal).

What to Do:

Immediately contact a poison control center (1-800-222-1222) or seek emergency medical attention. Bring the product packaging with you.

Drug Interactions

🔴

Major Interactions

  • Warfarin (Coumadin) with Vitamin K (can decrease anticoagulant effect)
  • Certain anticonvulsants (e.g., phenytoin, phenobarbital) with Folic Acid (may reduce anticonvulsant levels)
  • Levodopa with high doses of Vitamin B6 (pyridoxine) (can reduce levodopa efficacy, though less common with carbidopa/levodopa)
🟡

Moderate Interactions

  • Tetracycline antibiotics with Calcium, Iron, Zinc (decreased absorption of antibiotic)
  • Quinolone antibiotics with Calcium, Iron, Zinc (decreased absorption of antibiotic)
  • Bile acid sequestrants (e.g., cholestyramine) with fat-soluble vitamins (decreased absorption of vitamins)
  • Orlistat with fat-soluble vitamins (decreased absorption of vitamins)
  • Proton pump inhibitors (PPIs) and H2 blockers with Vitamin B12 (decreased absorption of B12)
  • Diuretics (thiazide, loop) with certain minerals (e.g., potassium, magnesium, calcium)
  • Antiplatelet drugs (e.g., aspirin, clopidogrel) with high doses of Vitamin E (increased bleeding risk)
  • Iron supplements with Vitamin C (increased iron absorption, potentially to toxic levels in hemochromatosis)
đŸŸĸ

Minor Interactions

  • Antacids with iron (decreased iron absorption)
  • Alcohol with B vitamins (increased excretion of B vitamins)

Monitoring

đŸ”Ŧ

Baseline Monitoring

Dietary intake assessment

Rationale: To determine if supplementation is truly needed and to identify potential deficiencies.

Timing: Prior to starting supplementation, especially for high-dose or long-term use.

Relevant vitamin/mineral levels (e.g., Vitamin D, B12, Iron)

Rationale: If specific deficiency is suspected or to establish baseline for high-risk patients.

Timing: Prior to starting supplementation for specific deficiencies.

📊

Routine Monitoring

Clinical symptoms of deficiency or toxicity

Frequency: Ongoing

Target: Absence of symptoms

Action Threshold: Appearance of new or worsening symptoms; consult healthcare provider.

Specific vitamin/mineral levels (e.g., Vitamin D, B12)

Frequency: Periodically (e.g., every 3-6 months or annually) if treating a deficiency or using high doses.

Target: Within normal physiological range or target therapeutic range for deficiency.

Action Threshold: Levels outside target range; adjust dose or discontinue.

Renal and Hepatic Function Tests (e.g., creatinine, ALT/AST)

Frequency: Annually or as clinically indicated, especially with high-dose fat-soluble vitamins or in patients with pre-existing impairment.

Target: Within normal limits.

Action Threshold: Significant abnormalities; re-evaluate vitamin regimen.

đŸ‘ī¸

Symptom Monitoring

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Headache
  • Fatigue
  • Skin rash
  • Yellowing of skin (carotenemia from excess Vitamin A)
  • Nerve damage (from excess Vitamin B6)
  • Increased bleeding/bruising (from excess Vitamin E)
  • Kidney stones (from excess Vitamin C or D)

Special Patient Groups

🤰

Pregnancy

Essential for maternal and fetal health. Specific prenatal vitamins are recommended, which contain appropriate levels of folic acid, iron, and other nutrients. High doses of certain vitamins (e.g., Vitamin A in retinol form) can be teratogenic.

Trimester-Specific Risks:

First Trimester: Crucial for neural tube development (folic acid). High doses of Vitamin A (retinol) are teratogenic.
Second Trimester: Continued need for iron and other nutrients for fetal growth.
Third Trimester: Increased iron needs to prevent maternal anemia and support fetal blood volume.
🤱

Lactation

Generally safe and often recommended to ensure adequate nutrient intake for both mother and infant. Specific lactation supplements are available. Consult a healthcare provider.

Infant Risk: Low risk with typical doses; high doses of certain vitamins could potentially transfer to breast milk and cause adverse effects in the infant (e.g., excess Vitamin D).
đŸ‘ļ

Pediatric Use

Use age-appropriate formulations. Accidental overdose, especially of iron-containing multivitamins, is a leading cause of poisoning in young children. Keep out of reach of children.

👴

Geriatric Use

May have increased needs for certain vitamins (e.g., Vitamin B12 due to decreased absorption, Vitamin D due to reduced skin synthesis and dietary intake). Caution with high doses due to potential for accumulation and drug interactions.

Clinical Information

💎

Clinical Pearls

  • Advise patients that multivitamins are supplements, not substitutes for a healthy diet.
  • Emphasize the importance of taking multivitamins with food to enhance absorption and minimize gastrointestinal upset.
  • Educate patients about the risks of exceeding recommended doses, especially for fat-soluble vitamins (A, D, E, K) and iron, which can accumulate and cause toxicity.
  • Counsel patients to inform their healthcare providers about all supplements they are taking, including multivitamins, to avoid potential drug-nutrient interactions.
  • For patients with specific deficiencies, targeted single-vitamin supplementation may be more appropriate than a general multivitamin.
🔄

Alternative Therapies

  • Dietary modifications to increase nutrient intake from food sources.
  • Specific single-vitamin or mineral supplements for targeted deficiencies (e.g., Vitamin D, B12, Iron, Calcium).
💰

Cost & Coverage

Average Cost: $5 - $30 per 30 tablets
Generic Available: Yes
Insurance Coverage: Generally Over-The-Counter (OTC) and not covered by insurance unless prescribed for a specific medical condition or deficiency.
📚

General Drug Facts

If your symptoms or health issues persist or worsen, it is essential to contact your doctor for further guidance. To ensure your safety, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about this medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the overdose, including the medication taken, the amount, and the time it occurred.