Albuterol 0.083%(2.5mg/3ml) 25x3ml

Albuterol is a selective beta2-adrenergic agonist. It acts by stimulating beta2-adrenergic receptors in the smooth muscle of the bronchi, leading to activation of adenyl cyclase and an increase in intracellular cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, inhibition of mediator release from mast cells, and some inhibition of microvascular leakage, resulting in bronchodilation.

Urgent Side Effects: Seek Medical Help Right Away

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of high blood pressure, including:
+ Severe headache
+ Dizziness
+ Fainting
+ Changes in eyesight
Signs of low potassium levels, such as:
+ Muscle pain or weakness
+ Muscle cramps
+ Abnormal heartbeat
Chest pain or pressure
Fast or abnormal heartbeat
Severe breathing problems, which can be life-threatening, especially when using an inhaler or liquid for breathing in. This may occur shortly after taking a dose or when using a new canister or vial of this medication. If you experience trouble breathing, worsening breathing, wheezing, or coughing, seek medical help immediately.

Other Possible Side Effects

Like all medications, this drug can cause side effects. While many people may not experience any side effects or only minor ones, it's essential to discuss any concerns with your doctor. If you experience any of the following side effects or any other symptoms that bother you or do not go away, contact your doctor:

Feeling nervous and excitable
Dizziness or headache
Upset stomach or vomiting
Shakiness
Throat irritation
Runny nose

This is not an exhaustive list of possible side effects. If you have questions or concerns about side effects, consult your doctor. You can also report side effects to the FDA at 1-800-332-1088 or online at https://www.fda.gov/medwatch.

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, any of its components, or other drugs, foods, or substances. Be sure to describe the allergic reaction you experienced, including any symptoms that occurred.
If you are currently taking another medication similar to this one. If you are unsure, consult your doctor or pharmacist for clarification.

Please note that this is not an exhaustive list of all potential interactions with this medication. To ensure your safety, it is crucial to discuss the following with your doctor and pharmacist:

All prescription and over-the-counter medications you are taking
Any natural products or vitamins you are using
* Any existing health problems you have

Before starting, stopping, or changing the dose of any medication, including this one, you must consult with your doctor to confirm that it is safe to do so in conjunction with your other medications and health conditions.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. To ensure safe use, do not exceed the prescribed dose or frequency, as overdoses have been fatal. If you experience any concerns, consult your doctor immediately.

If you find that your usual dose is not providing adequate relief, your symptoms are worsening, or you need to use this medication more frequently than prescribed, notify your doctor right away.

If you have diabetes (high blood sugar), it is crucial to closely monitor your blood sugar levels while taking this medication.

Before taking this medication, inform your doctor if you are pregnant, planning to become pregnant, or are breast-feeding. Your doctor will discuss the potential benefits and risks of this medication to both you and your baby, allowing you to make an informed decision.

• Beta-blockers (e.g., Propranolol, Carvedilol): May block the bronchodilatory effect of albuterol and produce severe bronchospasm, especially in patients with asthma. Concurrent use is generally contraindicated.
• Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (TCAs): May potentiate the cardiovascular effects of albuterol (e.g., increased heart rate, blood pressure). Use with extreme caution or avoid within 14 days of MAOI/TCA discontinuation.

• Diuretics (e.g., Thiazide diuretics, Loop diuretics): May potentiate the hypokalemic effect of albuterol, especially at high doses. Monitor potassium levels.
• Digoxin: Albuterol may decrease serum digoxin levels. Monitor digoxin levels.
• Other sympathomimetics (e.g., Epinephrine, Pseudoephedrine): Additive cardiovascular effects. Use with caution.

• Wheezing
• Shortness of breath (dyspnea)
• Chest tightness
• Cough
• Palpitations
• Tremor
• Nervousness

Albuterol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. While animal studies have shown some adverse effects, human data are limited. It is often considered a necessary medication for acute asthma exacerbations during pregnancy.

Albuterol is excreted into human milk, but at low levels. The amount ingested by the infant is likely to be small and unlikely to cause adverse effects. Generally considered compatible with breastfeeding.

Albuterol inhalation solution is widely used and effective in children aged 2 years and older for the treatment of bronchospasm. Dosing is weight-based or age-based. For children under 2 years, use is off-label and requires careful consideration and supervision by a specialist.

Elderly patients may be more sensitive to the effects of sympathomimetic amines, particularly cardiovascular effects (e.g., tachycardia, palpitations, hypertension). Use with caution, starting with the lowest effective dose and monitoring for adverse effects.

• Albuterol is a 'rescue' medication for acute symptoms, not a maintenance therapy for daily control of asthma or COPD.
• Increased use of albuterol (e.g., needing it more than twice a week, or waking up at night due to symptoms) is a key indicator of worsening asthma control and necessitates a re-evaluation of the patient's long-term controller therapy.
• Educate patients on the difference between rescue inhalers (albuterol) and controller medications (e.g., inhaled corticosteroids).
• Proper nebulizer technique is crucial for effective drug delivery. Ensure patients understand how to use and clean their nebulizer.
• Patients should be advised to seek immediate medical attention if their symptoms worsen after using albuterol or if they experience severe side effects.

• Levalbuterol (Xopenex): R-isomer of albuterol, may have fewer side effects (e.g., less tachycardia, tremor) in some patients.
• Other Short-Acting Beta2-Agonists (SABAs): e.g., Metaproterenol (less common).
• Anticholinergics (e.g., Ipratropium bromide): Can be used alone or in combination with albuterol for acute bronchospasm, particularly in COPD.
• Systemic Corticosteroids: For severe acute exacerbations.
• Long-Acting Beta2-Agonists (LABAs): Used for maintenance therapy, not acute relief (e.g., Salmeterol, Formoterol).
• Inhaled Corticosteroids (ICS): Used for maintenance therapy to reduce inflammation (e.g., Fluticasone, Budesonide).

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication. Some medications may come with an additional patient information leaflet, so it's a good idea to check with your pharmacist for more information. If you have any questions or concerns about your medication, don't hesitate to reach out to your doctor, nurse, pharmacist, or other healthcare provider. In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When seeking help, be prepared to provide details about the medication taken, the amount, and the time it happened.