Adderall 5mg Tablets

Amphetamines are non-catecholamine sympathomimetic amines that exert their therapeutic effect by increasing the release of norepinephrine and dopamine from presynaptic nerve terminals in the brain, particularly in the prefrontal cortex. They also block the reuptake of these monoamines into the presynaptic neuron, leading to increased concentrations in the synaptic cleft. The exact mechanism by which they produce their therapeutic effects in ADHD and narcolepsy is not fully understood but is thought to involve modulation of attention, impulse control, and wakefulness.

Urgent Side Effects: Seek Medical Help Right Away

Although rare, some people may experience severe and potentially life-threatening side effects while taking this medication. If you notice any of the following symptoms, contact your doctor or seek immediate medical attention:

Signs of an allergic reaction, such as:
+ Rash
+ Hives
+ Itching
+ Red, swollen, blistered, or peeling skin with or without fever
+ Wheezing
+ Tightness in the chest or throat
+ Trouble breathing, swallowing, or talking
+ Unusual hoarseness
+ Swelling of the mouth, face, lips, tongue, or throat
Signs of high blood pressure, including:
+ Severe headache
+ Dizziness
+ Passing out
+ Changes in eyesight
Signs of a urinary tract infection (UTI), such as:
+ Blood in the urine
+ Burning or pain while urinating
+ Frequent or urgent need to urinate
+ Fever
+ Lower stomach pain
+ Pelvic pain
Other severe side effects, including:
+ Difficulty getting or maintaining an erection
+ Changes in sex interest
+ Seizures
+ Trouble controlling body movements
+ Trouble controlling sounds, such as humming, throat clearing, yelling, or making loud noises
+ Restlessness
+ Changes in eyesight
+ Prolonged or frequent erections
+ Changes in skin color, such as pale, blue, gray, purple, or red discoloration
+ Numbness, pain, tingling, or cold sensation in the hands or feet
+ Sores or wounds on the fingers or toes
+ Muscle pain or weakness, dark urine, or difficulty urinating

Important Heart-Related Warnings

If you have a pre-existing heart condition or heart defect, inform your doctor. Additionally, if a family member has a history of abnormal heartbeat or sudden death, notify your doctor. Seek immediate medical attention if you experience any signs of heart problems, such as:

Chest pain
Abnormal heartbeat
Shortness of breath
Severe dizziness or passing out

Other Possible Side Effects

While many people may not experience side effects or only have mild side effects, it's essential to be aware of the following:

Feeling nervous and excitable
Headache
Trouble sleeping
Constipation, diarrhea, stomach pain, upset stomach, vomiting, or decreased appetite
Feeling dizzy, tired, or weak
Dry mouth
Bad taste in the mouth
Weight loss

If any of these side effects or other symptoms bother you or persist, contact your doctor for guidance. Remember, this is not an exhaustive list of possible side effects. If you have concerns or questions, consult your doctor.

Reporting Side Effects

To report side effects, you can:

Call your doctor for medical advice
Contact the FDA at 1-800-332-1088
* Visit the FDA's MedWatch website at https://www.fda.gov/medwatch

Before Taking This Medication: Important Information to Share with Your Doctor

It is essential to inform your doctor about the following:

Any allergies you have, including allergies to this medication, its components, or other substances, such as foods or drugs. Describe the allergic reaction and its symptoms.
A history of certain health conditions, including:
+ Blood vessel disease
+ High blood pressure
+ Heart structure problems or other heart-related issues
+ Tourette's syndrome or tics (you or a family member)
Presence of specific health conditions, such as:
+ Glaucoma
+ Agitation
+ Anxiety
+ Overactive thyroid
Past health issues, including:
+ Drug abuse
+ Stroke
Kidney disease
Current or recent use of certain medications, including:
+ Acetazolamide
+ Sodium bicarbonate
+ Certain antidepressants or Parkinson's disease medications (e.g., isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline) within the last 14 days, as this may lead to very high blood pressure
+ Linezolid or methylene blue
* Breast-feeding status: Do not breast-feed while taking this medication.

This list is not exhaustive. It is crucial to discuss all your medications (prescription, over-the-counter, natural products, and vitamins) and health problems with your doctor and pharmacist to ensure safe use. Never start, stop, or change the dose of any medication without consulting your doctor.

It is essential to inform all your healthcare providers, including doctors, nurses, pharmacists, and dentists, that you are taking this medication. This will help ensure your safety and prevent any potential interactions with other treatments.

When you first start taking this medication, be cautious when driving or performing tasks that require alertness and clear vision, as it may affect your ability to do so. Wait until you understand how this medication affects you before engaging in such activities.

Long-term or high-dose use of this medication can lead to tolerance, where the medication becomes less effective, and you may need higher doses to achieve the same effect. If you notice that the medication is not working as well as it used to, contact your doctor. Do not take more than the prescribed dose, as this can lead to adverse effects.

Prolonged or regular use of this medication may cause dependence, and stopping it abruptly can result in withdrawal symptoms. If you need to reduce the dose or stop taking this medication, consult your doctor, who will provide guidance on how to do so safely.

Before starting this medication, you may need to undergo heart tests to ensure your safety. If you have any questions or concerns, discuss them with your doctor.

This medication may cause an increase in blood pressure. Monitor your blood pressure and heart rate as directed by your doctor, and have regular blood tests to check for any potential effects.

It is crucial to inform all your healthcare providers and laboratory personnel that you are taking this medication, as it may affect the results of certain lab tests. Additionally, do not take antacids while taking this medication, as they may interact with it.

Some individuals taking this medication may experience changes in behavior or mood, such as altered thinking, anger, or hallucinations. If you or a family member have a history of mental health issues, such as depression or bipolar disorder, or if a family member has committed suicide, inform your doctor. Seek immediate medical attention if you experience hallucinations, changes in behavior, or signs of mood changes, such as depression, suicidal thoughts, nervousness, emotional instability, abnormal thinking, anxiety, or loss of interest in life.

This medication may increase the risk of seizures in some individuals, particularly those with a history of seizure disorders. Discuss your risk with your doctor to determine if you are more susceptible to seizures while taking this medication.

A rare but potentially life-threatening condition called serotonin syndrome can occur if you take this medication with certain other drugs. Seek immediate medical attention if you experience symptoms such as agitation, balance problems, confusion, hallucinations, fever, abnormal heartbeat, flushing, muscle twitching or stiffness, seizures, shivering or shaking, excessive sweating, severe diarrhea, nausea, vomiting, or severe headache.

In some cases, this medication may affect growth in children and adolescents. Regular growth checks may be necessary, and your doctor will discuss the potential risks and benefits with you. Different brands of this medication may be suitable for different age groups, so consult your doctor before giving this medication to a child.

Before consuming alcohol while taking this medication, discuss the potential risks with your doctor. If you are pregnant or plan to become pregnant, inform your doctor to discuss the benefits and risks of using this medication during pregnancy.

• Monoamine Oxidase Inhibitors (MAOIs) - risk of hypertensive crisis (do not use within 14 days of MAOI)
• Linezolid (reversible MAOI activity)

• Serotonergic drugs (SSRIs, SNRIs, TCAs, fentanyl, lithium, tramadol, triptans, St. John's Wort) - risk of serotonin syndrome
• Antihypertensives - may reduce hypotensive effects
• Urinary acidifiers (e.g., ammonium chloride, ascorbic acid) - increase amphetamine excretion, decrease efficacy
• Urinary alkalinizers (e.g., sodium bicarbonate, acetazolamide, thiazide diuretics) - decrease amphetamine excretion, increase toxicity
• Proton Pump Inhibitors (PPIs) and H2-receptor antagonists - may increase amphetamine absorption and exposure
• Antipsychotics (e.g., haloperidol, chlorpromazine) - may antagonize stimulant effects
• Propoxyphene - risk of seizures and psychosis

• Tricyclic Antidepressants (TCAs) - may increase cardiovascular effects of amphetamines
• Antacids - may increase amphetamine absorption
• CYP2D6 inhibitors (e.g., quinidine, fluoxetine, paroxetine, ritonavir) - may increase amphetamine exposure and risk of adverse effects
• Alcohol - may increase risk of adverse cardiovascular events
• Opioids - potential for additive CNS depression

• Caffeine - additive stimulant effects
• Decongestants (e.g., pseudoephedrine, phenylephrine) - additive sympathomimetic effects

• Chest pain
• Shortness of breath
• Syncope
• Palpitations
• New or worsening aggression
• Hallucinations
• Delusions
• Mania
• Severe anxiety
• Depression
• Unexplained weight loss
• Growth deceleration (in children)
• Numbness, coolness, or pain in fingers or toes (Raynaud's phenomenon)

Use during pregnancy should be avoided unless the potential benefit justifies the potential risk to the fetus. Amphetamines may cause fetal harm.

Amphetamines are excreted into breast milk. Due to the potential for serious adverse reactions in breastfed infants (e.g., irritability, poor feeding, sleep disturbances, growth suppression, cardiovascular effects), breastfeeding is not recommended during treatment with Adderall.

Safety and efficacy established for ADHD in children 3 years and older, and for narcolepsy in children 6 years and older. Long-term use in children has been associated with growth suppression (weight and height). Monitor growth regularly.

Use with caution in elderly patients. Elderly patients may be more sensitive to the cardiovascular and CNS stimulant effects. Consider lower initial doses and slower titration. Monitor for adverse effects, especially cardiovascular and psychiatric.

• Individualize dosage: Start low and titrate slowly based on patient response and tolerability.
• Timing of doses: Administer the last dose of the day at least 4-6 hours before bedtime to minimize insomnia.
• Drug holidays: Consider periodic drug holidays (e.g., weekends, school breaks) to assess the need for continued therapy, minimize growth suppression in children, and reduce tolerance.
• Monitor for diversion and abuse: Due to Schedule II classification and abuse potential, monitor for signs of misuse, abuse, or diversion.
• Cardiovascular risk: Screen all patients for pre-existing cardiac conditions and monitor BP/HR regularly. Avoid use in patients with symptomatic cardiovascular disease or moderate to severe hypertension.
• Psychiatric risk: Monitor for emergence or worsening of psychiatric symptoms, especially in patients with a history of psychosis, bipolar disorder, or severe anxiety.
• Growth monitoring: Essential for pediatric patients on long-term therapy.

• Methylphenidate (e.g., Ritalin, Concerta, Focalin)
• Lisdexamfetamine (Vyvanse)
• Atomoxetine (Strattera)
• Guanfacine extended-release (Intuniv)
• Clonidine extended-release (Kapvay)
• Bupropion (Wellbutrin) - off-label for ADHD
• Modafinil/Armodafinil (for narcolepsy)

If your symptoms or health issues persist or worsen, it is essential to contact your doctor promptly. To ensure safe and effective treatment, never share your medication with others or take someone else's medication.

This medication is accompanied by a Medication Guide, a patient fact sheet that provides crucial information. It is vital to read this guide carefully and review it again whenever your prescription is refilled. If you have any questions or concerns about this medication, consult your doctor, pharmacist, or other healthcare provider for guidance.

In the event of a suspected overdose, immediately call your local poison control center or seek emergency medical attention. When reporting the incident, be prepared to provide detailed information, including the name of the medication taken, the quantity, and the time it occurred.